This crosslinking mechanism has been used to produce tissue sealants from polymers that are commonly used in tissue engineering studies — fibrinogen and gelatin (Elvin et al. 2011; Elvin et al. 2010), but so far, there have been relatively few studies using Ruthenium - mediated crosslinking
for cell encapsulation.
Not exact matches
She is now developing new biomaterials which support
cell regrowth, nano -
encapsulation for targeted release of drugs and new drug candidates
for skin and aging applications.
Research Focus: My PhD research was focused on the microfluidic
encapsulation of stem
cells for regenerative medicine.
In an effort to improve this, we employed an alginate
encapsulation strategy
for human mesenchymal stem
cells (hMSCs) and attached them to the heart with a biocompatible PEG hydrogel patch in a rat MI model.
The
encapsulation of pancreatic islets within mainly alginate - based macro - or microcapsules with various physical configurations may allow protecting the islet graft without the need
for immunosuppressive agents and moreover expanding the donor pool to animal tissue and novel insulin - producing
cells.
Exploitation of alternative
cell sources (xenogeneic primary islets, stem
cell derived beta
cells)
for utilization in our
encapsulation device (collaboration with Anthony Gavalas, CRTD)
* Contains practical, hands - on information
for tissue engineers and students * Provides comprehensive protocols covering numerous topics, including polymer synthesis,
cell culture,
encapsulation, bioreactors, therapeutics, and the creation of tissues and organs * Includes contributions by leaders in the latest areas of research, such as stem
cells and fetal tissue engineering
Its core expertise is in efficient differentiation and
encapsulation of human stem
cells for therapeutic applications in diabetes.