Sentences with phrase «for cell maintenance»

High - quality pet foods are specially formulated to provide your dog with all of the nutrients he needs for cell maintenance and growth and good overall health, including proteins, fatty acids, carbohydrates, vitamins, and minerals.
The researchers compared mutation rates in the HPRT gene, which is important for cell maintenance.

Not exact matches

Protein helps to rebuild cells and tissue and is required for growth and maintenance.
Again, the Eilersen load cells are installed without mounting kits, which ensures a simple, hygienic installation minimising bacteria traps while eliminating the need for maintenance and reducing the total cost of ownership.
The Eilersen load cells feature EHEDG compliant hygienic design to provide a simple and hygienic installation without bacteria traps while eliminating the need for maintenance as the load cells are installed without expensive and complicated mounting kits.
The Eilersen measurement principle results in robust load cells that can tolerate up to 1,000 % overload, which allows for a very simple and hygienic mechanical installation, eliminating the need for maintenance and reducing the total cost of ownership.
Eilersen load cells feature excellent specifications, high reliability, simple installation and minimal maintenance for use in tough and demanding industrial environments.
While some previous studies found that maintenance lenalidomide after autologous hematopoietic stem cell transplant improved overall survival for newly diagnosed multiple myeloma patients, others showed no benefit to this approach.
For this analysis, 605 patients with newly diagnosed multiple myeloma and treated with continuous lenalidomide (brand name Revlimid) following autologous stem cell transplant were compared to 604 patients who were treated with placebo or no maintenance.
«Lenalidomide maintenance following autologous stem cell transplant can now be considered a standard of care for people with multiple myeloma,» says Dr. McCarthy, senior author on the meta - analysis and Principal Investigator of the U.S. study, CALGB (Alliance) 100104.
«By analyzing mice with the WNT10A mutation, as well as tissues from human patients with WNT10A mutations, we found that WNT10A regulates the proliferation, but not the maintenance, of stem cells in hair follicles,» said Sarah Millar, PhD, vice chair for Basic Research in the Department of Dermatology.
Scientists already knew interleukin - 6 influenced T follicular helper cell development, and they also knew interleukin - 7 was important for memory maintenance, ensuring memory cells persist for years after an initial infection.
Day in and day out, in our bodies, the DNA in cells is damaged for a variety of reasons, and thus intercellular DNA - repair systems are fundamental to the maintenance of life.
This technological advance will provide investigators with a new tool for comprehensive mapping of cell - cell communication, which is important in all aspects of cancer development, maintenance, and response to therapy.
The research, published online May 26 by Nature Immunology, shows that GATA - 3 is required for the maintenance and function of CD8 + T - cells, a T - cell type mediating the immune response to clear pathogens, eradicate tumors and promote inflammation.
Researchers have identified a population of «progenitor» cells in the skin that are solely responsible for the generation and maintenance of touch - sensing Merkel cells.
The fact that the bone lining cells, as target cells for oestrogen, play a role in bone maintenance confirms this suspicion.
Bacteria have genes that are necessary for the maintenance of cell shape, but most help build the cell wall, not internal scaffolds.
BPTF, identified by Dos Santos and colleagues as essential for mammary stem cell maintenance, is a protein with a very specialized function.
Kruppel - like factor 4 (KLF4) is required for maintenance of breast cancer stem cells and for cell migration and invasion
KLF4 is one of IPS genes that are required for maintenance of stemness of progenitor cells (27, 28).
The researchers also showed that a gene called TCF1 was important for the generation and maintenance of the PD -1-responsive T cells in mice.
While scientists have long known that a group of transcription factors are needed for stem cell maintenance, the sheer number of possible interactions among them has made the question of which are essential too complicated to address in the laboratory alone.
A kinetoplastid - specific kinesin is required for cytokinesis and for maintenance of cell morphology in Trypanosoma brucei.
Fusion of biological membranes is an essential process required for basic functions like transport of material within the cell, maintenance of cellular homeostasis and communication between cells.
«Additionally, these findings point to a promising strategy for delivering stem cells to targeted niches for their long - term maintenance and generation of functional cells through augmented stem cell competition.»
Researchers have demonstrated that the enzymatic activity of R5 receptor - type protein tyrosine phosphatases is a requisite for the maintenance of stem cell properties and tumorigenicity in glioblastoma cells and could be a promising drug target for treatment.
In contrast to mouse vRGs, which produce 10 to 100 daughter cells during brain development, a single human oRG can produce thousands of daughter neurons, as well as glial cells — non-neuronal brain cells increasingly recognized as being responsible for a broad array of maintenance functions in the brain.
Visualize intracellular lipid gradients in living cells and elucidate the molecular mechanisms required for their initiation and maintenance
The cell end marker TeaA and the microtubule polymerase AlpA contribute to microtubule guidance at the hyphal tip cortex of Aspergillus nidulans for polarity maintenance.
Regina Duryagina (Bornhäuser, TUD)-- «Role of Jagged - 1 and extracellular matrix components for the maintenance of hematopoietic stem and progenitor cells during ex-vivo expansion» (2013)
Further phenotypic characterization revealed that LKB1 is required for the differentiation and maintenance of two NCC - derivatives, Schwann cells and the ENS. Using a model of neural crest stem cell line, we demonstrated that Lkb1 is key for neural crest - derived glial commitment.
We offer defined and xeno - free laminin cell culture matrices for reliable expansion of pluripotent cell and differentiation and maintenance of specialized cell types
Dr Véronique Azuara has worked for several years in the field of developmental biology and genetics moving from lymphocyte development (PhD training at the Pasteur Institute — Paris) to epigenetic studies (post-doctoral training at the MRC / Clinical Sciences Centre — London) to explore how chromatin shut down contributes to lineage restriction and maintenance of cell fate identity through development.
She joined Dr. Rik Derynck's lab at the University of California San Francisco, as a postdoctoral researcher to explore the mechanisms of TGF - b signaling for the maintenance of human ES / iPS cell pluripotency.
Arndt K, Grinenko T, Mende N, Reichert D, Portz M, Ripich T, Carmeliet P, Corbeil D, Waskow C. CD133 is a modifier of hematopoietic progenitor frequencies but is dispensable for the maintenance of mouse hematopoietic stem cells.
This protocol is used for general maintenance and passaging of hES and iPS cells in a feeder - independent culture system such as mTeSR1 / Matrigel.
A lot is known about the transcription factors important for self - renewal and maintenance of neural stem cells, but drugging these is notoriously difficult.
Correct DNA methylation patterns are paramount for the generation of functional gametes capable of forming viable offspring, but also for the regulation of pluripotency states and the maintenance of genome architecture and expression in somatic cells.
The embryonic Drosophila central nervous system similar to the human spinal cord is a paradigm for understanding the cellular processes and genetic pathways regulating the formation and maintenance of a diverse population of nerve cells.
We conclude that the presence of T cells is not required for the differentiation and migration of resident skin DC but is critical for the maintenance of DC and LC migrating into the LNs.
Compared to MEF cells, which can be maintained for only 5 — 7 days after irradiation, HFF cells as a feeder layer avoid frequent passage and allow the maintenance of established cell - cell interaction during the reprogramming process.
«The observed increase in the ratio of cytotoxic CD4 T cells to CD4 helper T cells indicates that they are an important component of the protective immune response to viral infections and that their induction should be an important marker for successful vaccinations against certain viral diseases,» says postdoctoral researcher and first author Veena Patil, Ph.D. «But we really didn't know enough about their molecular profile and the mechanisms that drive their differentiation and maintenance
«We hope this research will help inform clinicians into congenital defects related to the formation and maintenance of arteries and veins, and may also yield new strategies that can coax the development of arteries from stem cells — which may prove useful for treating coronary artery disease.»
The direct vascularization of the implanted cells is expected to allow for robust and consistent engraftment but will necessitate the use of maintenance immune suppression therapy.
The cell - cycle regulator c - Myc is essential for the formation and maintenance of germinal centers.
Previous work has shown that precise levels of Oct4 transcript and protein are required for ES cell maintenance; raising or lowering levels within a narrow window is sufficient to induce differentiation or de-differentiation, respectively [14].
Allogeneic cell therapies from primary cells for immunotherapy applications are especially challenging because of the vigor with which tissue donors must be screened and qualified to prevent transmission of infectious disease and ensure maintenance of an active donor pool.
Adult stem cells serve as a reservoir of cells for repair of damaged tissue throughout the life of an individual, but the maintenance and regeneration of tissues, such as skin, liver, blood and muscle, dramatically decrease with age.
Adult stem cells are essential for the maintenance and regeneration of organs and tissue.
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