We performed a visual screen of ∼ 2000 transposon mutants of C. jejuni
for cell shape mutants.
«The degree to which our discoveries linked interacting systems and provided clear explanations
for cell shape control was great.
Dr Sánchez - Corrales» search for an adequate mathematical representation
for cell shape led the group to discover there were inherent errors in quantifying shape properties through a traditional method named the Elliptic Fourier Analysis, named after Joseph Fourier the French mathematician and physicist.
Not exact matches
While you are making adjustments
for your changing
shape, there are a lot of changes going on inside your womb as your baby, who was just a cluster of
cells a couple of months ago, has organs, nerves, muscles and is looking more like a little person.
This unnatural and forced movement of water changes vaginal
cell shape and biology
for the worse and can lead to tissue damage, irritation, and general disruptions to the vaginal ecosystem.
An interactive pillow... perfectly
shaped for my kido, a little pocket
for my
cell phone and some added loops
for extra toys to be the ultimate distraction
for diaper changes.
Instead of preparing to form fingers and toes and a brain like the rest of the embryo's
cells, these ones are destined to form a disc -
shaped organ that's chock - full of blood vessels and will take over
for the corpus luteum in the second trimester: the placenta.
Thanks to their «smart pockets,» I have mesh pockets
for visibility, zipper pockets to slow down a curious baby, a magnetic closure pocket
for when I want to quietly grab my stuff, a
cell phone pocket, and pockets of all
shapes and sizes.
That development is important because a T
cell response will likely confer longer - term protection than current inoculations do and defend against a variety of flu strains (because T
cells would be on the lookout
for several different features of the flu virus whereas antibodies would be primarily focused on the
shape of a specific strain).
Donald Ingber, M.D., Ph.D., Founding Director of the Wyss Institute at Harvard University, started investigating this «architecture of life» over thirty - five years ago, and discovered that Nature uses an architectural principle known as «tensegrity» (short
for «tensional integrity») to stabilize the
shapes of living
cells and to determine how they respond to mechanical forces.
For instance, to make a rod with collagen fibers aligned along its length (like a tendon) they cultured chondrocyte
cells in a dog bone -
shaped mold with loops on either end.
So far, researchers with the Allen Institute
for Brain Science in Seattle have described the intricate
shapes and electrical properties of about 100 nerve
cells, or neurons, taken from the brains of 36 patients as they underwent surgery
for conditions such as brain tumors or epilepsy.
Lagasse, based at Pitt's McGowan Institute
for Regenerative Medicine, has discovered how to turn any one of the body's 500 lymph nodes — the small, oval -
shaped organs where immune
cells gather to fight invading pathogens — into an incubator that can grow an entirely new liver.
Once researchers understand the rules
for how to get specific
shapes with TZPs that also assemble into larger structures, they can design materials with desired functions —
for example, a membrane
for a battery, a catalyst
for a fuel
cell, or even a therapeutic drug.
The
shape and chemical composition of these granules is identical to organelles found in
cells called melanosomes; these being responsible
for creating and storing the pigment melanin.
The finding could help engineers and materials scientists produce solar
cells and other opto - electronics without the help of the high temperatures required to
shape glass today — making this ancient arrangement a boon
for modern technology.
A technician then examines the sample under a microscope
for the oddly -
shaped cells that are a precursor to cancer.
This role in memory formation adds to the repertoire of these starburst -
shaped cells, once believed to be responsible
for only providing food and support to more important brain
cells (SN Online: 8/4/15).
He and colleagues have determined what gives cholera bacteria their curved
shape and whether it matters (a polymer protein, and it does matter; the curve makes it easier
for cholera to cause disease), how different wavelengths of light affect movement of photosynthetic bacteria (red and green wavelengths encourage movement; blue light stops the microbes in their tracks), how bacteria coordinate
cell division machinery and how photosynthetic bacteria's growth changes in light and dark.
The team looked
for these
cells in nonliving brain samples in two ways: molecular markers that tag dividing
cells and young nerve
cells, and telltale
shapes of newborn
cells.
We employ similar pathways to
shape our parts as embryos, but over the course of evolution, humans may have lost the ability to tap into it as adults, perhaps because the
cell division required
for regeneration elevated the likelihood of cancer.
Although not nearly as well studied as neurons, astrocytes — named
for their star -
shaped appearance — make up one - third to one - half of all the
cells in the brain and are increasingly being found to be critical
for neuronal function.
Her team is currently investigating what physiological consequences this
shape - changing might have
for Hydra's
cells.
Nevertheless, as Tobias says, it is still ``... a field beset with relatively few facts but many theories... The story of early hominid brains has to be read from carefully dated, well identified, fossilised calvariae, or from endocranial casts formed within them... Such materials confine the Hercule Poirot, who would read «the little grey
cells» of fossil hominids, to statements about the size,
shape and surface impressions... of ancient brains...» The other major limiting factor at the moment is the lack of suitable fossil skulls
for such studies.
Losing a genetic switch that increases production of a protein called GDF6 may have created the big toe and helped
shape the human foot
for bipedalism, scientists propose in a paper published online January 7 in
Cell.
Living
cells are like miniature factories, responsible
for the production of more than 25,000 different proteins with very specific 3 - D
shapes.
«Overlooked
cell key player in preventing age - related vision loss: Tree -
shaped retinal
cells called Müller glia may provide a new therapeutic target
for treating degenerative eye diseases.»
These neurons and the synapses between them are supported by long, tree -
shaped cells called Müller glia (in green), which may provide a new therapeutic target
for treating degenerative eye diseases.
Star -
shaped brain
cells called astrocytes, usually dismissed as support
cells for the attention - grabbing neurons, now seem to control the growth of new neurons in adult brains.
Day 0: Around 9,000 stem
cells are transferred into V -
shaped wells and suspended in a cocktail of vitamins, amino acids and (
for the first six days) Y - 27632, a chemical to prevent the stem
cells from committing suicide.
Sheldrake's basic folly, argues Wolpert, is that he is pushing the notion of morphic resonance at precisely the time when strictly biochemical analysis of
cell structure and organization is close to providing a comprehensive explanation
for morphogenesis, the process by which living creatures acquire their
shapes.
MERS CoV (CoV stands
for coronavirus) has on its surface an array of spike -
shaped proteins that bind to host
cells — specifically to receptor proteins called DPP4 on the surface of
cells that line human airways.
Being able to adequately quantify and compare the
shapes of
cells or organisms is of ultimate importance
for biology, says Dr Grieneisen.
Blood
cells stored
for transfusion also change
shape as they age.
For example, the hippocampal place
cell representation of location was previously found to respond continuously to changes in environmental
shape alone.
While researchers at the Georgia Institute of Technology don't have a specific application
for the doughnut -
shaped droplets yet, they believe the novel structures offer opportunities to study many interesting problems, from looking at the properties of ordered materials within these confined spaces to studying how geometry affects how
cells behave.
These two, almond -
shaped clumps of nerve
cells deep in the brain are sometimes referred to as the emotional thermostat
for their role in the processing of emotions, particularly fear.
Once inside, the proteins fold into their proper
shape and are shuttled to the
cell membrane
for release.
Though single -
celled organisms blanket the Earth and are capable of impressive biochemistry — some can eat nuclear waste,
for example — their structure and
shape remain simple.
Astrocytes, named
for their star - like
shape, are ubiquitous brain
cells known
for regulating excitatory synapse formation through
cells.
In a paper published Sept. 21 in
Cell, Harvard Medical School genetics professor Olivier Pourquié — whose lab discovered the segmentation clock 20 years ago — and colleagues report that they used mouse
cells to reconstitute a stable version of this clockwork
for the first time in a petri dish, leading to several new discoveries about where the clock is located, what makes it tick and how the vertebral column takes
shape.
Artificial muscles made with carbon nanotubes or a
shape memory alloy can be designed to act as fuel
cells, thus alleviating a need
for a remote battery power source.
For instance, a
cell tuned to an axis where nose width and eye size changed wouldn't respond to changes in lip
shape.
In addition, when the structure of the flies» ears was examined in detail, the researchers discovered that nerve
cells of the noise - rattled flies showed signs that they had been exposed to stress, including altered
shapes of the mitochondria, which are responsible
for generating most of a
cell's energy supply.
Cells in a developing embryo have different shapes and behaviors and can be densely packed, making it difficult for a computer to identify and track individual c
Cells in a developing embryo have different
shapes and behaviors and can be densely packed, making it difficult
for a computer to identify and track individual
cellscells.
Apart from advancing our understanding of how plants regulate their growth and
shape, this research presents new questions
for stem
cell researchers in regards to
cell size checkpoints and their importance during organism development.
If you rub your eyes too much, you send random, meaningless noise to your brain, and all the
cells for all the
shapes begin screaming at once.
As genetic circuitry
shapes up, scientists hope the new device will make it easier
for them to program
cells to do things such as watch
for disease, monitor pollution, or even turn on medicine output.
Some of these
cells lost their star
shape and began to form new nerve
cells in a brain region responsible
for smell.
The research team found that this non-coding RNA fragment maintains healthy
cells through two mechanisms: Firstly by regulating the levels of DIRAS3, one of its neigboring genes that is involved in
cell replication; secondly by suppressing a network of genes that prepare
cells to change their
shape and prepare
for metastasis.