Sentences with phrase «for cellular processes»

Ribose is the structural backbone of ATP, the primary form of energy used for all cellular processes.

With scientists just starting to unveil the molecular frameworks for cellular processes, «we have no clear pictures of what the stem cells are doing throughout the day,» he says.

For example, instead of using a water - based substance as a basis for its cellular processes, a Martian organism might use hydrogen peroxide, a molecule similar to perchlorate that is abundant on Mars.

Living cells use phosphate to transport cellular energy with adenosine triphosphate (ATP), necessary for every cellular process that uses energy.

Not exact matches

Yeo explained that you need to prepare someone's finger for this process to make sure blood is flowing, but if you end up squeezing the finger too hard or have to prick it too many times, that may damage and break down cells — and this cellular damage could skew various test results.

[37] Fletcher explained «Natural selection is in fact a chemical process as well as a biological process, and it was operating for about half a billion years before the earliest cellular life forms appear in the fossil record.»

The cryotherapy process reduces inflammation for pain relief and improved mobility by decreasing the cellular metabolism, pain and spasm while increasing cellular survival and the levels of oxygenated blood delivered to damaged tissue.

Close collaboration between the Pasteur Institute and Inria, taking the form of the InBio join research group, whose aim is to develop a methodological framework for achieving a quantitative understanding of the functioning of cellular processes, is the perfect illustration of the value of interdisciplinary research combining experimental approaches with methodological developments.

It is still a long road to approved therapies but a growing body of basic research is fueling a search for drugs that interact with cellular cleanup processes to provide one - size - fits - all approaches for treating a megaclass of brain disorders.

Visualizing cellular components and processes at the molecular level is important for understanding the basis of any biological activity.

So - called functional RNA is important for almost all cells and cellular processes, for example, by binding proteins or performing catalytic processes.

The authors hypothesize that these activities are components of cellular reconfigurations that are involved in processing communication signals essential for social organization.

«Because it acts at a deeper level within the cellular process it takes longer for it to get started again.»

Proteins called kinesins, for example, are natural nanomotors that support cellular functions such as mitosis (the chromosomal process that creates two nuclei from one parent nucleus) and meiosis (when the number of chromosomes per cell is reduced by one half).

In order for cellular life to emerge and then evolve on earth, the fundamental building blocks of life needed to be synthesised from appropriate starting materials — a process sometimes described as «chemical evolution».

If researchers can unlock the secrets of this cellular process, therapies that replace diseased cells with healthy ones may one day be possible — brain - cell transplants to combat Alzheimer's, for instance, or even the creation of whole organs from scratch.

Recently, researchers have begun to describe the function of autophagy, a cellular recycling process critical for homeostasis, in germline stem - cell proliferation of C. elegans.

Dr Christos Gkogkas, a Chancellor's Fellow in the University of Edinburgh's Centre for Discovery Brain Sciences, said: «Our study reveals that altered protein synthesis through eIF4E is a key cellular process in the brain that can go awry in depression.

«TIA - 1 is known for its ability to regulate gene expression during cellular stress,» says Hewett, who studies the processes that suppress the severe electrical storms in the brain, leading to seizures.

«We have already demonstrated that these two synapses process different types of information that in turn is likely to comprise the cellular mechanisms for memory encoding and retrieval at these synapses» explains Hardy Hagena.

Dr. Jan Höpker, Dr. Silke Oeljeklaus, Prof. Dr. Nikolaus Pfanner, Dr. Sebastian Stiller, Prof. Dr. Bettina Warscheid, Prof. Dr. Nils Wiedemann and their team of researchers have demonstrated that this protein complex is essential for the integration of certain proteins into the inner membrane of mitochondria — proteins that play a role in cellular respiration and other processes.

Among their many functions, signaling pathways regulate biological processes required for cellular survival.

This year's Nobel Prize in Physiology or Medicine has been awarded to Yoshinori Ohsumi, a cell biologist at the Tokyo Institute of Technology's Frontier Research Center, for his work on autophagy, the process in which cells degrade and recycle cellular components.

Because the amount of ROS present in cells is tightly regulated by iron - dependent processes in the mitochondria (the cellular compartments in which energy is generated), the researchers had proposed iron import into the mitochondria to be essential for this process.

The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.

Such experiments suggest that deletion of cellular activity, even for a brief time, «is causally involved with a pathological process like narcolepsy,» Boyden said.

The detailed study of such fundamental cellular processes is crucial for the understanding of diseases that go hand in hand with these events — in the case of autophagy, Alzheimer's disease or cancer.

The latest frontier in this search for cancer telltales is the cellular process of endocytosis, which is the way cells take outside materials like proteins inside.

«There is evidence showing the disease interrupts the process providing the primary cellular energy source necessary for cell function and survival.»

«This camera has the potential to greatly enhance our understanding of very fast biological interactions and chemical processes that will allow us to build better models of complex, dynamical systems such as cellular respiration, or to help doctors better deliver and monitor light - based therapies,» says Richard Conroy, Ph.D., program director for Optical Imaging at NIBIB.

If the antitoxin is degraded, triggered for example by adverse environmental conditions, the toxin becomes effective and inhibits important cellular processes.

Chemists from Radboud University Nijmegen, Eindhoven and Paris now show for the first time that random variations or «noise» in cellular processes come to exist because of an interplay between the rate of the reaction and its environment.

One likely place to look for an answer was histones, to see if changes in the patterns of the chemical marks on them might reveal any secrets, at the cellular level, of the aging process we all experience — and, perhaps, whether there might be anything we can do about it.

In 2011, UT Southwestern researchers in Dr. Levine's laboratory identified the protein Smurf1 as important for the elimination of viruses and damaged mitochondria from cells via a cellular housekeeping process called autophagy.

Manipulating biological processes with minimal interference, from the cellular level to the behavior of whole organisms, is a burgeoning scientific effort to better understand how living things work and to develop more effective treatments for a range of medical disorders.

«The idea is to initiate specific biochemical processes in cells by flipping a magnetic switch,» says Jon Dobson, a biomedical engineer who has been manipulating cellular function with magnetic particles for more than 10 years at Keele University in Staffordshire, England.

Dr. Maria Iribarne, first author of this study, commented: «The gosh mutant is a good model for understanding the molecular and cellular mechanism of cone cell death and the pathological process of human LCA.

The role of academic scientists in this process has largely been to explain the genetic / cellular basis of diseases for identifying useful targets and provide new chemical and computational methods to improve the pharmacological profile of potential drugs.

Traditional hydrogels made up of either synthetic polymers or natural biomolecules often serve as passive scaffolds for molecular or cellular species, which render these materials unable to fully recapitulate the dynamic signaling involved in biological processes, such as cell / tissue development.

«While it is well - established that obesity generates cellular and molecular stress leading to abnormal functioning of many cellular processes, the mechanisms remain incompletely understood,» said senior author Gökhan S. Hotamisligil, chair of the Department of Genetics and Complex Diseases and the Sabri Ülker Center for Nutrient, Genetic, and Metabolic Research.

Yang and co-author Chunru Lin, Ph.D., an assistant professor in the same department, confirmed four sites for phosphorylation, a process that turns protein enzymes off and on, impacting key cellular functions.

Autophagy is a self - degradative process for cellular homeostasis.

Only from these results can the team deduce which conditions are crucial for the development of complex life and whether Earth is the ideal place for the necessary cellular processes.

«We were able to use a set of cutting - edge tools to gain insight into a critical cellular process for normal brain development, the dysregulation of which may be a manifestation of a genetic predisposition for schizophrenia,» says senior author Dr. Guo - li Ming, of Johns Hopkins University School of Medicine.

The common cellular energy source Adenosine Triphosphate, or ATP, had been used in all other observed ubiquitination and was thought necessary for the process, he said.

The addition of a small protein named ubiquitin can mark another protein for destruction, relocation in the cell, or it can turn the protein on or off, which can trigger or stop a cellular process, Luo said.

During those years, the way we study fundamental biological processes underwent a major shift that has now culminated in sequenced human genomes, knowledge of many cellular processes, and a clear path to unraveling roles for individual molecules.

It is caused by a mutation in the ACVR1 gene, which over-activates a cellular signaling process that is important for embryo development and involves a protein called BMP.

Construction of somatic cellular knockout models for the determination of protein functional impacts on various cellular processes:

Bits of misfolded proteins processed by specialty organelles may accumulate in the main compartment of the cell, the cytosol, where they can be tagged for disposal by the cellular garbage service.