Sentences with phrase «for cellular reprogramming»
It was from those, they concluded, that they could identify the genes responsible for cellular reprogramming.
https://www.sciencedaily.com/ Not exact matches
Scientists have rolled back time for live mice through systemic cellular reprogramming, according to a study published December 15 in Cell.
«Stem cell reprogramming factor controls change in cellular energy generation: Research reveals role for KLF4 protein in instructing cells to undergo metabolic changes while acquiring stem cell characteristics.»
Furthermore, direct cellular reprogramming increases the potential for reprogramming that would occur inside a patient rather than in a dish.
«This study shows how our teams are leveraging synthetic biology not only to reprogram microbes to create living cellular devices that can carry out useful functions for medicine and environmental remediation, but to do this in a way that is safe for all,» said Wyss Institute Founding Director Donald Ingber, M.D., Ph.D., who is also the Judah Folkman Professor of Vascular Biology at HMS and the Vascular Biology Program at Boston Children's Hospital, as well as Professor of Bioengineering at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS).
For example, cellular reprogramming is an inefficient process because many of the target areas on the genome are covered by other proteins, like a childproof cap on a medicine bottle, which prevents the reprogramming factors from binding there.
Secondly, before considering the use of iPSC - derived organoids for transplantation / regenerative medicine in human patients, the current protocols for expansion, reprogramming and differentiation of iPSCs in long - term cultures need further improvement to minimize the risk of oncogenic cellular mutations and teratoma, or tumor formation, in the patient.
«The present study is a continuation of Yamanaka's recent work that contributes to our understanding of the basic science of cellular reprogramming, while also addressing one of the important issues to be tackled for this technology to be useful for medical research.»
The Ogawa - Yamanaka Stem Cell Prize recognizes individuals whose original translational research has advanced cellular reprogramming technology for regenerative medicine.
The excitement surrounding cellular reprogramming and the possibility of federal funding for human embryonic stem cell (ESC) research in the US could be overshadowing another promising therapeutic source of stem cells: those derived via parthenogenesis, some researchers say.
In recent years, the tools available for life science researchers have advanced at spectacular speed, and Gladstone pioneered several methods — consider cellular reprogramming and bioinformatics — that transcend any single disease.
Her winning essay in Science, «Hope for the Brokenhearted,» explains how cellular reprogramming has greatly enhanced the study of stem cells and regenerative medicine.
When I saw the spectrum of research at Gladstone — cellular reprogramming technologies, developmental biology, chemical biology, genome editing — that was happening in all these top - notch labs, I felt that it was really complementary to what we were doing and that there were immediate opportunities for synergies and collaborations.
Reprogramming of cellular identity using exogenous expression of transcription factors (TFs) is a powerful and exciting tool for tissue engineering, disease modeling, and regenerative medicine.