Sentences with phrase «for cellular signaling»

Gamma secretase inhibitors tend to produce adverse effects by interacting with Notch, an important pathway for cellular signaling.

TOR, in mammals called mTOR, is very important for cellular signalling and is implicated in various diseases such as cancer, diabetes, and neurodegeneration.

Thanks to these biocharacteristics, attachment of GAGs to biomaterials offers a great opportunity to modulate tissue response and create an appropriate environment for cellular signalling, both important issues in tissue engineering and regeneration.

Understanding the underlying mechanisms allows identifying putative sites for pharmacological intervention and opens the prospect of engineering artificial molecular switches derived from the highly efficient systems that have evolved for cellular signal transduction.

Like before, the rear casing is made from Apple's favoured material - anodised aluminium - which is only interrupted by the white or grey plastic casing at the top for the cellular signal to break through.

You will also notice that the status bar icon for the cellular signal has changed to just dots instead of signal bars.

Not exact matches

Unlike streaming services such as MobiTV or Verizon's VCast, China's mobile TV will transmit signals directly to a UHF / VHF antenna built into the phones, thus bypassing the cellular network and allowing for 50 times the bandwidth.

But the cellular technology giant predicted flat results for the June quarter, sending mixed signals to investors who are looking for some good news after months of turbulence...

She emphasized, however, that lay people need not understand, for example, the mechanics of cellular signaling in order to appreciate the potential importance of those events to human health.

A cell may receive a genetic signal to build a lipid for a certain cellular purpose, but the exact type may not be indicated with a high degree of specificity.

The authors hypothesize that these activities are components of cellular reconfigurations that are involved in processing communication signals essential for social organization.

HIF - 1 senses reduced oxygen levels and triggers many changes in cellular function, including a changed metabolism and sending signals for the formation of new blood vessels.

They showed that ZIKV infection of cortical progenitors (stem cells for cortical neurons) controlling neurogenesis triggers a stress in the endoplasmic reticulum (where some of the cellular proteins and lipids are synthetized) in the embryonic brain, inducing signals in response to incorrect protein con - formation (referred to as «unfolded protein response»).

Science Signaling offers researchers the most up - to - date resource for groundbreaking research and commentary in the multidisciplinary field of cellular sSignaling offers researchers the most up - to - date resource for groundbreaking research and commentary in the multidisciplinary field of cellular signalingsignaling.

The M - current is mediated through cellular potassium channels and is important for the proper firing of neuronal signals.

Information theory analysis of cell signaling reveals mechanisms for reliable cellular responses despite signal variability.

Those deletions tended to involve genes that affect cilia, cellular structures that are important for signaling and patterning in embryonic development.

Meanwhile, cancer genome projects have yielded unprecedented insights into the cellular signaling pathways that drive the development and progression of cancer — information that has led to effective therapies tailored for individual patients.

Among their many functions, signaling pathways regulate biological processes required for cellular survival.

This study reveals how lipids control SH2 domain - mediated cellular protein interaction networks and suggests a new strategy for the therapeutic modulation of pY - signaling pathways.

The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.

With entry categories for science / healthcare workers and the under 25s as well as professional and amateur photographers, the competition is an opportunity to stimulate an interest in any area of science, from planetary movements to cellular signalling or more general topics such as physics or the environment, as well as demonstrating artistic flair.

However, this approach is inefficient and complicated, relies on ill - defined cellular signals, lacks reproducibility, and is not scalable or suitable for clinical - grade cell manufacturing.

Scientists use it as a model organism for studying cellular signals, disease, and the movement of cells in response to a chemical stimulus (chemotaxis).

NIGMS has awarded $ 5 million a year for 5 years to a group of scientists studying cellular signaling.

«For the first time, we now have cellular evidence of abnormal signaling in cells derived from women with PMDD, and a plausible biological cause for their abnormal behavioral sensitivity to estrogen and progesterone,» explained SchmiFor the first time, we now have cellular evidence of abnormal signaling in cells derived from women with PMDD, and a plausible biological cause for their abnormal behavioral sensitivity to estrogen and progesterone,» explained Schmifor their abnormal behavioral sensitivity to estrogen and progesterone,» explained Schmidt.

Traditional hydrogels made up of either synthetic polymers or natural biomolecules often serve as passive scaffolds for molecular or cellular species, which render these materials unable to fully recapitulate the dynamic signaling involved in biological processes, such as cell / tissue development.

It is caused by a mutation in the ACVR1 gene, which over-activates a cellular signaling process that is important for embryo development and involves a protein called BMP.

It often requires a second signal for them to commit to a single cellular identity.

Dr. Subramaniam is head of database developments under The Alliance for Cellular Signaling, a multi-institution, multidisciplinary project, utilizing a multitude of high throughput approaches to obtain context - specific knowledge of cellular response to input.

The Cell Surface Signalling Laboratory is interested in identifying new therapeutic targets for both genetic and infectious diseases by using large - scale systematic approaches to discover receptor - ligand interactions that are essential for cellular recognition processes.

The BMP protein acts as an activator for cell — surface receptors, and initiates cellular processes and signaling cascades.

D. Höglinger, A. Nadler & C. Schultz Caged lipids as tools for investigating cellular signaling BBA 2014, published online

The Cell Surface Signalling Laboratory investigates the molecular basis of cellular recognition processes to identify new therapeutic targets for both genetic and infectious diseases.

This landmark revelation was the first definition of an entire cellular signaling pathway from the cell surface to the nucleus, providing an important paradigm for understanding intracellular signaling.

«This is the only system I know about that is amenable for structural work on how the cellular signal comes down to the chromatin and DNA and that can provide an answer about how a signal activates a eukaryotic gene,» Panne says.

In the worm, we are developing tools to monitor neuromodulation at cellular resolution in an intact brain and using them to directly measure endogenous peptide release and binding to receptors on identified neurons using real - time approaches for imaging neuropeptide signaling, in order to understand the dynamics of this process in a living animal.

The team at UW has previously showed how an ambient backscatter technique can convert existing TV and cellular signals into electricity, allowing for battery - free sensors to be embedded into objects.

Since then, Dong has established his small lab as a key player among researchers interested in the assembly of the centriole, a barrel - shaped cellular structure central to the formation of cilia, antenna - like cell surface protrusions essential for cell motility and signal transduction.

For example, the same cellular signals that guide early heart development can be used to direct stem cells to become the different heart cell types needed for modeling disease in a diFor example, the same cellular signals that guide early heart development can be used to direct stem cells to become the different heart cell types needed for modeling disease in a difor modeling disease in a dish.

By defining the processes behind these cellular signals, the blueprint for the heart, we hope to one day recreate them through chemical methods — using drug cocktails to coax stem cells into becoming heart cells at just the right time and place.

The Center for Cell Circuitry addresses the enormous therapeutic potential of cellular circuits, which connect individual molecular components and allow cells to process signals and control decision - making.

Setton also identified a gene, called arrow, that when disrupted set off a cascade of cellular signaling events suggesting for the first time important relationships between segmentation and leg - development genes found across insects and arachnids.

Moreover, the data can serve as a basis for studies concerning the evolution of signaling mechanisms, as well as can give specific insights into the regulation of basic cellular processes such as polar cell growth, cell expansion, plant morphogenesis and the plants responses to fungal pathogens.

This is known as cellular swelling and has also been shown to be an anabolic signal for muscle growth.

This is a way of slowing down the aging - related processes, improves brain functioning and memory capacity, strengthens and stabilizes cellular membranes which is crucial for cell signaling and energy transfer.

Autophagy, the body's mechanism for the removal and recycling of cellular waste, is key to rejuvenation, especially in the mitochondria, and is allowed to proceed only in the postabsorptive state, in which insulin signaling ebbs to its lowest (basal) level.

In the membrane theory of diabetes, saturated fatty acid for the diet are deemed responsible for rigid cellular membranes that in turn impair insulin signaling.

When an acute injury has taken place, the cellular inflammatory pathways signal the body to send red and white blood cells to the injured area in order for healing to take place.

Calcium is used for many cellular signals in the body, and that may extend to the receptiveness of glycogen stores to insulin molecules.