Sentences with phrase «for cellular therapy»

As a monolayer of cells critical to photoreceptor function and survival, the RPE is an ideally accessible target for cellular therapy.

The cell processing track aims at reproducible, safe and sustainable methods applicable in manufacturing settings for cell - based products intended for cellular therapy.

But new research with kidney transplant patients provides a proof of principle for a cellular therapy that may eliminate the need for antirejection drugs.

«New liver cell for cellular therapy to aid in liver regeneration.»

Nonetheless, because they can be obtained in a non-invasive manner, and in large quantities, they offer much potential for cellular therapies.

«In addition, the data presented are also endorsing iPSC as being equally powerful tools for cellular therapies and regenerative medicine as hESC, providing a final proof for which the field was looking for years.»

Not exact matches

And there have been developments in cellular therapies to treat cancer, with two treatments aiming for approval by the end of 2017.

It is still a long road to approved therapies but a growing body of basic research is fueling a search for drugs that interact with cellular cleanup processes to provide one - size - fits - all approaches for treating a megaclass of brain disorders.

Research has led to discoveries in the use of antioxidant therapy as a proactive measure to counteract the production of free radicals and thus stave off the potential for prolonged cellular damage.

Pediatric physicians and heart surgeons are the first to admit that these basic cellular findings don't translate into an immediate therapy for these newborns.

CML stem cells, the cellular source of a vast majority of differentiated CML cells, are reportedly responsible for the recurrence of CML, following TKI therapy.

Meanwhile, cancer genome projects have yielded unprecedented insights into the cellular signaling pathways that drive the development and progression of cancer — information that has led to effective therapies tailored for individual patients.

«Alcohol prevents ability to extinguish fearful memories in mice: Insight into cellular mechanisms illuminates biological target for PTSD therapy.»

If researchers can unlock the secrets of this cellular process, therapies that replace diseased cells with healthy ones may one day be possible — brain - cell transplants to combat Alzheimer's, for instance, or even the creation of whole organs from scratch.

Celgene's pipeline includes several oral drugs for solid tumors and hematologic cancers and cellular therapies for Crohn's disease, multiple sclerosis, rheumatoid arthritis, and sarcoidosis.

Wahl was on the tenure track in 2002 as a pathology researcher at Duke University, identifying cellular targets for cancer therapies, when funding dried up for her research and she consequently failed to get tenure.

A challenge in developing iron chelators for use in human therapy is to reduce iron accumulation without disrupting iron - dependent cellular functions.

Additionally, since ribosomal RNA has been shown to have specified controlled of cellular fate, this study provides a theoretical basis for disease therapy and neuroscience research and may lead to future advances in treating degenerative diseases or even brain cancers.

«This camera has the potential to greatly enhance our understanding of very fast biological interactions and chemical processes that will allow us to build better models of complex, dynamical systems such as cellular respiration, or to help doctors better deliver and monitor light - based therapies,» says Richard Conroy, Ph.D., program director for Optical Imaging at NIBIB.

«It would be very difficult for the virus to develop resistance against a therapy that targets a cellular protein,» says Palese.

Aptamers are also being selected against specific cellular receptors for use in cancer therapy.

With cellular therapy holding enormous promise for future cures and treatments, Black Beret Life Sciences is committed to doing what it can to help the field reach its full medical potential by creating a more efficient regulatory framework in the U.S.

The accessibility of the retina, together with imaging technologies makes it a prime candidate for developing cellular therapies for central nervous disorders.

Our research is located at the interface of immunology and stem cell research and our recent findings lay the groundwork for new cellular therapy approaches in regenerative medicine.

For 2018, the CIMT program committee is preparing plenary sessions from pre-clinical research to clinical development on the topics of therapeutic vaccination, cellular therapy, improving immunity, tumor microenvironment, antibodies, regulatory research and immunoguiding.

Basically what was happening when you use a hematopoietic stem cell to correct an inherited metabolic disease is that through engraftment of that cell you are allowing that cell to become the replacement source for the missing enzyme or other factor - almost like a cellular form of gene therapy or, as I call it, «poor man's gene therapy».

Our research goal is to understand the molecular and cellular events required for pancreatic β - cell regeneration, and apply this knowledge towards the development of cell replacement therapies for diabetes.

AFM supports each year more than 400 research programs, among them more than 30 clinical trials in gene therapy or cellular therapy concerning for example muscular, eyes, skin or blood diseases.

Apart from the various biomedical applications of nanomaterials, especially in cancer therapy, cellular uptake of nanoparticles is a key factor in recent years for efficient drug delivery applications.

«I highly respect Novocell technologies and am pleased to collaborate with Novocell and explore the potential of their hES cell to islet cell advances in combination with our iPS cells as a potential new sources for the generation of cellular models and therapies for diabetes,» said Dr. Yamanaka, Director of Center for iPS Research and Application at Kyoto University.

The cellular processes that we have identified in this study as being important for the development of stomach cancer provide new targets for therapy that have not been explored before,» Dr. O'Reilly said.

Areas covered by Cancer Cell include, but are not limited to, molecular and cellular mechanisms of cancer, mechanisms for the sensitivity and the resistance to cancer therapies, and development of better cancer therapies.

The SMDC has allowed Gladstone scientists to design molecules to modulate the functions of proteins or specific cellular phenotypes and, most significantly, screen for drugs that could be used as therapies for disease.

Inventors at MUSC have identified a unique human CD4 + T cell population that expresses high levels of surface CD26, termed CD26high T cells, which mediate durable antitumor immunity in vivo, and have immediate clinical relevance for designing new vaccines and cellular therapies.

The restriction of cellular growth by p53 has been reported to result in cell cycle arrest or apoptosis [6], and targeting p53 and restoring p53 function to limit tumor growth has been intensively researched for cancer therapy [7].

Therefore, this work provides strong support for the use of iPSC ‐ derived MSC as a more uniform with well ‐ defined phenotype and function as a sustainable source of cells which paves the way for a clinical application for IBD cellular therapy.

Targets of research range from basic molecular and cellular mechanisms, the manipulation of these mechanisms in animal models, analyses of the genes and gene products in cardiovascular disease, and clinical research that seeks to improve diagnosis and therapy for patients.

«People who undergo chemotherapy or radiation therapy for oral cancer often lose their sense of taste, leading to decreased interest in food, weight loss, and malnutrition,» said lead author M. Hakan Ozdener, M.D., Ph.D., M.P.H., a cellular biologist at Monell.

It is poised to become a major site for research and early development of personalized cellular therapies for cancer.

Novocell has developed and proven methods to efficiently generate pancreatic, insulin - producing cells from hESCs, demonstrating for the first time that hESCs could serve as a source of cellular therapy for diabetes.

Dr. David Maloney, medical director for cellular immunotherapy at Fred Hutch and the Bezos Family Immunotherapy Clinic, talks about the promise of new therapies.

My laboratory seeks to better understand the pathological interplay of human retroviruses like human immunodeficiency virus (HIV) and human T - cell lymphotropic virus (HTLV) with their cellular hosts with the goal of providing new approaches for prophylaxis and therapy.

These findings have identified an alternative source of replacement tissue for use in human retinal cellular therapies, and provide a new in vitro cellular model system in which to study RPE diseases affecting human patients.

For human tissue regeneration to become a viable therapy for conditions like neurodegeneration or diabetes, clinicians will likely need to artificially manipulate factors that return adult brain or pancreatic cells to a cellular «Tir Nan Og» to restore adult cell typFor human tissue regeneration to become a viable therapy for conditions like neurodegeneration or diabetes, clinicians will likely need to artificially manipulate factors that return adult brain or pancreatic cells to a cellular «Tir Nan Og» to restore adult cell typfor conditions like neurodegeneration or diabetes, clinicians will likely need to artificially manipulate factors that return adult brain or pancreatic cells to a cellular «Tir Nan Og» to restore adult cell types.

Dr. Jain's nominators note that, in sum, his work has provided ``... unprecedented molecular, cellular, anatomical and functional insights into the vascular pathophysiology of tumors, for proposing the seminal hypothesis that antiangiogenic therapy can «normalize» the aberrant vasculature and microenvironment of tumors and thereby improve both delivery and efficacy of treatment of solid tumors.»

Human ES cells may become the basis for far - reaching progress in cellular therapy.

A 2010 British study conducted by the Herbal Research Centre showed a 25 % + increase in cellular magnesium levels in participants who used transdermal magnesium therapy for 12 weeks.

I mix practical experience of metabolic therapies with a detailed understanding of its potential for cancer management and seizure control at the cellular level.

Light therapy (how we use it) helps activate an important metabolic enzyme called cytochrome c oxidase, which is essential for healthy cellular energy production, and relaxation.

The IV therapy consists of amino acids (the natural building block of protein) combined with vitamins and nutrients is administered intravenously in order to flood the brain, restoring neurotransmitters, manufacturing new neurotransmitters and receptors which promotes healing of the damaged area of the brain and allows for increased cellular energy production.