Because Sonic Hedgehog might be an indicator of tumor growth, targeting this protein could be clinically beneficial
for choroid plexus carcinoma treatment.
Not exact matches
«However, in clinical neuroscience, the functions of
choroid plexus beyond cerebrospinal fluid generation have been largely neglected;
for example, the size of the
choroid plexus is not quantified in routine brain scans,» explains Professor Riitta Hari, who was in charge of the research.
Fiona Doetsch's group uncovered that the
choroid plexus secretes a wide variety of important signaling factors in the CSF, which are important
for stem cell regulation throughout life.
Sanford Research scientists are published in Nature Cell Biology
for their work developing a model to explore therapies
for a pediatric brain tumor known as
choroid plexus carcinoma.
Located in the walls of the brain ventricles, the
choroid plexus is best known
for producing cerebrospinal fluid, which forms a protective mechanical cushion and immunological buffer
for the brain.
We were intrigued by the occurrence of hydrocephalus in the brains of these mice and began to investigate the structures within the brain that might be involved — the
choroid plexus and the ciliated ependyma,» said corresponding author Alessandra d'Azzo, Ph.D., who holds the Jewelers
For Children Endowed Chair in Genetics and Gene Therapy at St. Jude.
Choroid plexus papillomas have no apparent predilection
for brachycephalic.