Finally, within the fractionated cell populations, there was evidence
for coexpression of lineage specific markers alongside of pluripotency genes, similar to lineage priming described first in hematopoietic stem cells [15].
Not exact matches
The module colors indicate the
coexpression modules to which the genes belong, with the odds ratio and P - value given
for each module reflecting the overall enrichment
for differentially regulated genes in the module.
A thematic examination of the
coexpression modules enriched
for relaxation effect genes showed a suppression of correlated networks regulating stress responses, inflammation and wound healing.
Measures including psychological measures (depressive symptoms, perceived stress, vitality and mindfulness) and detailed methods
for the blood draw, processing, biomarker assays and RNA sequencing of blood samples are described in the Supplementary Appendix, along with all statistical analyses carried out
for group comparisons, construction of differential expression signatures, construction of
coexpression networks, construction of Bayesian networks and pathway enrichment analysis.
(a) The red, brown, pink and purple
coexpression network modules enriched
for the vacation signature were projected on a blood Bayesian network.
The pathway enrichment heatmap indicates the — log10 of the P - value
for pathways enriched in the indicated
coexpression module.
A Global
Coexpression Network Approach
for Connecting Genes to Specialized Metabolic Pathways in Plants