Sentences with phrase «for cytomegalovirus»

Not exact matches

Though hailed as «a new therapeutic principle» in 1990, it nonetheless took another eight years for the FDA to approve the first antisense drug, fomivirsen — for the treatment of AIDS - related retinitis caused by human cytomegalovirus.

The team is recruiting about 400 healthy people who will be screen for the relatively common cytomegalovirus.

Some research shows that moms who are exposed to cytomegalovirus for the first time during pregnancy may have a higher risk of miscarriage, but the relationship of CMV to miscarriage is not completely clear at this point.

Tanaka K, Yamada H, Minami M, Kataoka S, Numazaki K, Minakami H, Tsutsumi H. «Screening for vaginal shedding of cytomegalovirus in healthy pregnant women using real - time PCR: correlation of CMV in the vagina and adverse outcome of pregnancy.»

Depending on your medical history, tests may also be done for other infections such as cytomegalovirus or parvovirus.

Scientists have discovered a key molecule linked to Human Cytomegalovirus (HCMV) infection, which is harmless for healthy people but can cause miscarriage and birth defects during pregnancy.

Other infections also can cause microcephaly; in fact, out of 121 infants tested for other pathogens, 26 had evidence of infection with either toxoplasmosis, herpes simplex, cytomegalovirus, and syphilis.

Dwarki and Jaime Escobedo improved the AAV's ability to insert genes into chromosomes by adding a gene promoter region from cytomegalovirus, known to be active in the target for their gene therapy, muscle cells.

For someone with an underactive immune system, cytomegalovirus might rev things up just enough to fend off a harmful pathogen.

Based on the new study, it is hard to say if being infected with cytomegalovirus is good or bad for the immune system.

Also, septic patients with evidence of cytomegalovirus in plasma, a component of blood, had significantly higher 90 - day death rates than septic patients who tested negative for the virus, although it is not clear whether the cytomegalovirus contributed to the additional deaths.

A publication in the scientific journal Nature Microbiology identifies PDGFRα as the receptor for the trimeric gHgLgO complex of Human cytomegalovirus (HCMV).

That collaboration ultimately resulted in clinical trials to assess two compounds for treating cytomegalovirus (CMV) infections, which weaken the immune system.

However, the depletion of the patient's immune system prior to transplantation can put patients at risk of for an infection by a virus called cytomegalovirus (CMV) that can be life threatening in these immune - compromised individuals.

The two researchers found that schizophrenics often carried antibodies for toxoplasma, a parasite spread by house cats; Epstein - Barr virus, which causes mononucleosis; and cytomegalovirus.

The drugs dampen a certain inflammatory enzyme, which also proves essential for replication of human cytomegalovirus (CMV).

The researchers sought to explore the link between maternal infection and risk for autism, focusing on five pathogens known collectively as ToRCH agents — Toxoplasma gondii, rubella virus, cytomegalovirus, and herpes simplex viruses type 1 and 2 — to which exposure during pregnancy can lead to miscarriage and birth defects.

Human cytomegalovirus downregulates expression of receptors for platelet - derived growth factor by smooth muscle cells.

Lastly, increased systemic inflammation seen during ageing is also apparent in chronic infections such HIV or cytomegalovirus, 10,15 obesity7 and individuals enduring chronic psychological stress.16 Similarly, the main features of immunosenescence are apparent in many of these conditions, including decreased antibody responses, increased infections, malignancies and also incidences of inflammatory associated disorders such as cardiovascular disease.7, 10,15,16 Inflammation and premature immunosenescence are, therefore, prevalent features of many common conditions of modern life, such as obesity and stress, and could have negative health consequences for large proportions of society well before old age is reached.

Envelopment of human cytomegalovirus occurs by budding into Golgi - derived vacuole compartments positive for gB, Rab 3, trans - Golgi network 46, and mannosidase II.

Heidi's unrelenting style can be seen across all areas of Hookipa, including a major role in the clinical strategy, scientific advice and clinical trial application for the Vaxwave cytomegalovirus vaccine candidate HB - 101.

Polycomb Repressive Complex 2 Targets Murine Cytomegalovirus Chromatin for Modification and Associates with Viral Replication Centers.

We have completed the active phase of a Phase 1 trial of a Vaxwave ® - based vaccine against cytomegalovirus (CMV) and are finalizing clinical development plans for TheraT ® in Human Papilloma Virus (HPV)- related head and neck cancers.

Nucleolin associates with the human cytomegalovirus DNA polymerase accessory subunit UL44 and is necessary for efficient viral replication.

A Hex cDNA with a recognition sequence for bacterial BirA ligase was linked via an artificial IRES consisting of a tandem array of repeated Gtx sequences to the gene encoding Venus followed by a cytomegalovirus driven hygromycin - thymidine kinase dual selection cassette flanked by loxP sites.

In chronic Lyme and associated diseases Olive Leaf Extract (OLE) is an antimicrobial for acute viruses, like the cold and flu viruses, and chronic viral infections like Human Herpes Virus 6 (HHV - 6), Cytomegalovirus (CMV), and Epstein Barr Virus (EBV).

For example, concurrent infection with cytomegalovirus is recognized as a serious complication for HIV + individuals (Macallan et al 199For example, concurrent infection with cytomegalovirus is recognized as a serious complication for HIV + individuals (Macallan et al 199for HIV + individuals (Macallan et al 1993).

For the primates unfortunate enough to be kept in captivity like this, there is always a chance of developing diseases such as tuberculosis, hepatitis, simian herpes, SIV, cytomegalovirus, in addition to being subjected to abuse and isolation from their kin.

An infection with cytomegalovirus is usually harmless for adults.