Sentences with phrase «for differences in gene expression»

To see what genes might be involved in this increased aggression, the team used microarrays to look for differences in gene expression in fly brains.

They compared space - flown endothelial cells to endothelial cells cultured under normal gravity, looking for differences in gene expression and / or in the profile of secreted proteins.

Not exact matches

For example, the nuclei in the centers of the mutant organoids moved more slowly, and we saw significant differences in gene expression.»

What we were surprised to find out was that the real differences we could detect in terms of when we did the swap experiments to say which yeast could outperform the other — what we learned was that the GAL1 gene, that the part [of] that, the DNA sequence is outside of the GAL1 gene, it acts as a switch to turn up or turn down GAL1 expression, that had evolved considerably from the ancestral situation; and same for the GAL3.And then what had happened was that each function had been optimized, that GAL3 had sort have been tuned to be sort of a loosely regulated kind of available anytime sensor of galactose and GAL1 had evolved to be an incredibly tightly regulated, in fact, it's the most tightly regulated gene you know of in yeast.

A large body of research has reported that Nanog is allelically regulated — that is, only one copy of the gene is expressed at any given time — and fluctuations in its expression are responsible for the differences seen in individual embryonic stem (ES) cells» predilection to differentiate into more specialized cells.

Rather than listing specific genes that manifest themselves differently, or are differentially expressed, between queens and workers, the team looked for genes with similar expression patterns across samples that may be involved in maintaining the structural, behavioural and functional differences observed between queens and workers.

This information is not only important because it can now help scientists try to understand how the differences between queen and worker may arise through interactions among genes, but also for the evolution of ants, and in the evolution of gene expression more generally.

It's the first time scientists have shown in selectively bred animals that the propensity for addiction is linked to differences in expression of genes for specific molecules in a specific brain region.

For example, the researchers were able to identify previously unknown gene expression differences between the neural stem cells that give rise to the brain's deep structures versus its neocortical surface, and to show that molecular signatures of different neural cell types arise much earlier in brain development than previously realized.

In these images of rat brains, differences in gene expression of genes for fibroblast growth factor 2 (FGF2, top set) and dopamine 2 receptor (D2, bottom sett) can be seen in rats of two breeds before (left) and after (right) cocaine exposurIn these images of rat brains, differences in gene expression of genes for fibroblast growth factor 2 (FGF2, top set) and dopamine 2 receptor (D2, bottom sett) can be seen in rats of two breeds before (left) and after (right) cocaine exposurin gene expression of genes for fibroblast growth factor 2 (FGF2, top set) and dopamine 2 receptor (D2, bottom sett) can be seen in rats of two breeds before (left) and after (right) cocaine exposurin rats of two breeds before (left) and after (right) cocaine exposure.

Among older sets of twins, however, significant differences in the gene - expression portraits were apparent for 35 percent of the study group.

The team suspects the difference may be due to the expression of a gene that codes for a growth factor called bone morphogenetic protein 2 (Bmp2); expression was 30 % higher in the developing forelimbs of bats than it was in mice.

If, for instance, a researcher finds that dozens of genes in a microarray are differentially expressed on a high - fat purified ingredient diet compared to a low - fat GB diet, it is tempting to conclude that gene expression was altered due to the differences in fat levels between the diets.

The color band to the right of the heatmap indicates the mean difference in expression (DE) between the baseline and post-intervention time points for each of the differentially expressed genes.

The role of αCaMKII autophosphorylation in the establishment of alcohol addiction Alanna Easton, King's College, UK Novel age - dependent learning deficits in a mouse model of Alzheimer's disease: implications for translational research Karienn Montgomery, University of Florida, USA Microsatellite regions upstream of the vole Avpr1a gene contribute to both individual and species differences in receptor expression Zoe Donaldson, Columbia University, USA Per Genes and Addiction Stephanie Perreau - Lenz, Central Institute of Mental Health, Germany

«Based on our data, which is comprised of gene expression across 16 brain regions, we found that the most distinct region, i.e. the region where we observe more human - specific differences in gene expression, is the striatum, a region involved in motor coordination, reward, and decision - making,» lead author André M. Sousa of the Yale School of Medicine and the Kavli Institute for Neuroscience told Seeker.

The only clue indicating that differences in gene expression level are not the reason for the observed correlation between the recombination rate and the size of introns is that we do not see a comparable pattern when examining the size of exons, the number of exons per gene, and the overall size of proteins.

Differences between mRNA expression in testis of IVC and control males for several gene categories (A, B).

We considered a minimum ten fold difference in the expression levels of genes as a relevant criterion for classifying them as high and low expression genes.

Within the gene coding for MAOA, there is a particular form of variation (referred to as the MAOA - uVNTR) that is associated with differences in the expression of the MAOA gene (Sabol et al., 1998).