Sentences with phrase «for different alleles»

It requires as input a list of chromosomes and coordinates, and returns the count for different alleles among the genomes it references.

Not exact matches

«This study reveals for the first time a comprehensive picture of all active alleles in different tissues — we have uncovered the first complete allelome» Florian Pauler, now at ISTA (Institute of Science and Technology Austria) and co-senior author, adds.

For example, they revealed that most organisms have two copies of each gene, one from each parent, and that a gene comes in a variety of different forms, or alleles.

For one thing, each chromosome contains tens of thousands of different genes (or rather, alleles of different genes), and it will still be quite a few years before you can specify each single gene.

The existence of the vegetarian allele implies that, for people with this variation, straying from that diet — by eating a lot of red meat, for example — may make them more susceptible to inflammation, because their bodies were optimized for a different mix of inputs.

To investigate whether or not somatic coding mutations contributed to the different antigenicity observed between clones, the authors undertook an in silico analysis of predicted MHC class I binding affinity for each allele of missense mutations.

Yet each one tells a different story: (a), how novel - to - dbSNP variants were rare; (b), how nonsynonymous variant frequencies are shifted to lower values relative to those of synonymous variants, (c), how this shift in allele frequencies is more pronounced for damaging nsSNPs, consistent with natural selection, and (d), how the sizes of observed indels are enriched for non-frameshift events divisible by 3.

The identification of a single disease allele in 3 different MPDs prompted us to search for JAK2V617F mutations in CMML / aCML, AML, and MDS.

As long as some gene on a different chromosome does not interfere, all dogs with the dominant KB allele would be black in those areas of the coat where «dark» is called for, such as all over in some breeds or the saddle in other breeds.

Doing a genetic test and subsequently eliminating an individual from the breeding population may not be the best strategy, as by targeting a particular allele at one genetic locus for removal from the gene pool of a particular breed, breeders may in fact increase allele frequency of genetic variants on alternative haplotypes at the same, or a different locus, that are recessively deleterious.

Please note that there is no difference between these alleles in the coloration of a dog; for example, a dog that is bsbs will not appear different than a dog that is bdbd or bcbc.

Provision of two EBVs carries the additional possibility of balancing the two traits within breeding pairs (selection of a mate with complimentary EBVs for a breeding animal with substantially different genetic merit for «laxity» and «osteoarthritis») and the possibility of guidelines which aim to preserve alleles protective against osteoarthritic change in response to laxity.

The gene (allele) that codes for liver - chocolate expression of the otherwise black pigment is on a different part of the chromosome than is the gene for black / blue.

This is different from insurance and genetics where there are lots of data available for testing the probabilities of well - described events such as higher accident rates in a stratum, or higher disease rates with particular alleles.

Review: apolipoprotein E ε4 allele is a risk factor for Alzheimer's disease in different ethnic groups

Although the extent of X-inactivation in human brain is not known, these findings suggest that heterozygous low - high females are mosaic for different MAOA alleles and are likely to have intermediate enzymatic activity.