Not exact matches
Think of people declining to get tested
for the genetic
markers of a hereditary
disease, or a smoker whose cigarette packs might as well have that warning from the Surgeon General printed in invisible ink.
As well, many other gene
markers for grain - mediated injury have been described, thus placing many into the category of gluten intolerant, but not truly having celiac
disease.
The Malaysian researchers were aware of how reheated oils used over and over in deep fat fryers create hypertension (high blood pressure) and other
markers for cardiovascular
disease.
However, this study only included kids at high - risk
for celiac (based on genetic
markers or a first - degree relative with the
disease), so it might not apply to the general population.
Multiple genetic
markers have been identified
for celiac
disease, but many genetically susceptible individuals tolerate gluten and never develop symptoms, leading to speculation about other risk factors, including early childhood nutrition.
The Atlanta - based Centers
for Disease Control and Prevention, the federal agency that collects data on a range of other health
markers, only started tracking breastfeeding statistics in 1994.
A new study of 635 children in Massachusetts found that a bigger waist size at age 3 increases the odds that a child will have a
marker for liver damage and nonalcoholic fatty liver
disease by age 8.
The findings also give a biological
marker for the
disease that could possibly lead to an earlier intervention before the
disease manifests.
Individuals were classified as high risk
for Alzheimer's if a DNA test identified the presence of a genetic
marker — having one or both of the apolipoprotein E-epsilon 4 allele (APOE - e4 allele) on chromosome 19 — which increases the risk of developing the
disease.
Lennox studies how well, or how poorly, population cohorts comply with dietary guidelines and attempts to link eating patterns with cancer incidence, blood
markers for heart
diseases and diabetes, or body weight and blood pressure.
Now with an extensive and diverse collection of representative apple genomes, thorough and careful analyses have allowed Fei's group to distinguish important genetic
markers that will greatly aid breeders in their quest
for better apples — be it
for disease resistance, shelf - life, taste, or even size.
The company wanted to use it as a diagnostic
marker for disease: If synthetic versions of antibodies could be tagged with aequorin in the lab, then whenever they matched up with an antigen (or surface protein) of a specific pathogen in blood or tissue, the sample would glow.
«It's good to see this type of study advance, as we desperately need noninvasive and low - cost
markers for Alzheimer's
disease,» Hendrix says.
The
marker of antigens produced by pancreatic cancer has a low positive predictive value
for identifying early stage
disease.
In other words, she says, personality constructs emerging from the basic biology of the brain can be yet another
marker that the individual is at risk
for TILT, and easier to sensitize to the
disease.
«We hope that our work will provide the basis
for a larger study of patient samples that may ultimately identify biomarkers that can be used as surrogate
markers to determine the benefit of therapeutic interventions in diagnosed but asymptomatic HD patients to prevent or delay
disease onset.»
The researchers analyzed how the changes affected indicators of cardiovascular health, such as blood pressure, heart rate and other
markers for heart
disease and stroke, like high «bad» cholesterol levels.
Although tau imaging is still in its earliest stages, Ryan hopes that such imaging will accelerate drug development and that finding a blood - based biomarker
for Alzheimer's to reveal risk (much like cholesterol serves as a
marker for cardiovascular risk) will change the field dramatically in terms of how doctors can diagnose the
disease.
«Our analysis suggests that migraine should be considered an important risk
marker for cardiovascular
disease, particularly in women,» concludes Prof. Kurth, adding that: «The risk of developing cardiovascular events was shown to be 50 % higher in women with a diagnosis of migraine.
The concentration of these components can be a differentiating
marker between certain bowel
diseases and their accurate detection by way of non-invasive devices such as the electronic nose would be a great step forward
for the detection and monitoring of the evolution of these
diseases,» explains doctor Pilar Nos, Head of the Digestive System Medicine Department at La Fe hospital.
«This opens a new door in identifying biological
markers for dementia since we might consider using the brain's processing of speech sounds as a new way to detect the
disease earlier,» says Dr. Claude Alain, the study's senior author and senior scientist at Baycrest's Rotman Research Institute (RRI) and professor at the University of Toronto's psychology department.
For neuroscientists finishing a Ph.D. program or a postdoctoral position, the mysteries of neuronal circuits and genetic markers for disease pale compared to one puzzling question: Where are the jo
For neuroscientists finishing a Ph.D. program or a postdoctoral position, the mysteries of neuronal circuits and genetic
markers for disease pale compared to one puzzling question: Where are the jo
for disease pale compared to one puzzling question: Where are the jobs?
As a result, the emphasis in early development is on understanding the molecular underpinnings of
disease and developing
markers for therapeutic effects.
These discoveries build upon previous findings about genes linked to Alzheimer's, such as the APOE - 4 gene, which is a powerful
marker for late - onset Alzheimer's
disease; about 40 percent of those diagnosed have this DNA variant.
As Maurizio Battino, researcher at UNIVPM and Director of the study, said: «This is the first time a study has been published that supports the protective role of the bioactive compounds in strawberries in tackling recognised
markers and risk factors
for cardiovascular
diseases.»
The study also found distinct blood pressure patterns from ages 18 to 55 that reveal people at high risk
for calcification of coronary arteries — a
marker for heart
disease — by middle age.
«Our study suggests that short height in children is a possible
marker of stroke risk and suggests these children should pay extra attention to changing or treating modifiable risk factors
for stroke throughout life to reduce the chances of having this
disease,» said senior study author Jennifer L. Baker, Ph.D., associate professor in the Center
for Clinical Research and Prevention at Bispebjerg and Frederiksberg Hospital and Novo Nordisk Foundation Center
for Basic Metabolic Research, Faculty of Health and Medical Sciences, at the University of Copenhagen, in Denmark.
A detailed understanding of how TSPO binds to such
markers opens up novel paths
for diagnostic imaging and could constitute an important step along the way to early detection of such
diseases and inflammations.
By providing clues to the function of proteins, he says, the Atlas may accelerate their use as
markers for disease or drug targets.
Our results pointed to three new genetic
markers for FECD and confirmed the vital role of a previously known
marker even among those who did not have a previously known family history of the
disease.
While rapid point - of - care tests
for diagnosing sexually transmitted infections are commercially available today and used within developing regions, they tend not to be affordable or accurately quantify the concentrations of the
disease markers within a sample, which help to determine the stage of the infection.
They also evaluated the blood
for insulin resistance and two
markers of inflammation that are connected with
disease.
Now he looks at a whole range of possible genetic
markers for the
disease, in every patient taking part in every AD drug trial.
These results add to evidence that migraine should be considered an important risk
marker for cardiovascular
disease, say experts.
Nevertheless, the authors say «these results further add to the evidence that migraine should be considered an important risk
marker for cardiovascular
disease, at least in women,» and there is no reason why the findings can't be applicable to men.
The authors will follow up the study with additional worldwide populations to better understand the mutations and these genes as a genetic
marker for disease risk.
«Women with migraines have higher risk of cardiovascular
disease, mortality: Migraine should be considered an important risk
marker for cardiovascular
disease, say experts.»
While attending a conference, Orszag learned from biologist Craig Venter that he could get screened
for a genetic
marker that can raise the risk of heart
disease when lots of caffeine is consumed.
«We've got a
marker for biological aging — telomere length — so we're studying whether we can relate it to the increased risk of getting some of these age - associated
diseases.
These high - resolution maps and new techniques
for defining genetic
markers should greatly accelerate the hunt
for genes linked to
diseases.
«Our ability to pinpoint CRP levels as being significantly elevated before and after postoperative delirium onset establishes CRP as a risk
marker, as well as a
disease marker,
for delirium,» said Sarinnapha Vasunilashorn, co-first author of the study, along with Simon Dillon, also of BIDMC.
In past studies, he discovered that suPAR not only is a
marker for kidney
disease, but also a likely cause.
Next steps
for the team include identifying microbiota metabolites whose levels are either significantly elevated or depleted during
diseases such as IBD or cancer, to find
disease - specific
markers and explore possible roles
for these metabolites in
disease progression.
«The distinct neural
markers associated with cognitive performance and GWI revealed in our study can be useful
for future research to objectively measure the efficacy of treatments
for GWI as well as other brain disorders related to the same neurotransmitter system, like Alzheimer's
disease.»
Similar experiments could identify new
markers of
diseased tissue or new targets
for targeted molecular therapies.
Replicating Venter's $ 70 million technological feat is too costly
for most of us, and it's not clear what good it would serve to know that, like Venter, one has a genetic
marker for wet earwax — or Alzheimer's
disease, which can't be prevented or cured.
Researchers at the Ludwig - Maximilians - University, the German Center
for Neurodegenerative Diseases (DZNE), and the Institute
for Stroke and Dementia Research (ISD) in Munich, Germany, have identified a brain inflammation
marker in patients at early asymptomatic stages of Alzheimer's
disease.
A selection of Joe Davis's colorful «prayer flags,» which are printed with the code
for the genetic
markers of
diseases such as cancer, Parkinson's and Huntington's.
I am proposing a demanding criterion: that you be able to detect abnormalities in patients beforehand by such brain - imaging techniques as functional MRI [which measures blood flow in the brain], and then use imaging to see whether or not there is a change in those
markers for the
disease as the therapy progresses.
The researchers assessed the blood and urine samples of 70 people with the relapsing - remitting form of MS to check
for levels of salt; a
marker of inflammatory activity called creatinine; and vitamin D, low levels of which have been linked to the
disease.