Researchers will determine if common heart medications are an effective adjunct therapy
for dogs with hemangiosarcoma.
Due to the highly malignant nature and advanced state of disease (often to other organs), the prognosis
for dogs with hemangiosarcoma is quite guarded.
Despite considerable efforts to find effective treatments, the outcome
for dogs with hemangiosarcoma has changed very little over the past 30 years.
Despite considerable efforts by veterinarians and scientists to find effective treatments, the outcome
for dogs with hemangiosarcoma has changed very little over the past few decades.
Dog Studies CANCER Novel Therapies Common heart medications as an effective adjunct therapy
for dogs with hemangiosarcoma, an aggressive and deadly cancer.
Researchers at the University of Pennsylvania School of Veterinary Medicine treated dogs with a commercially available Coriolus versicolor product and found the longest reported survival time
for dogs with hemangiosarcoma.
Not exact matches
• increases the risk of cardiac
hemangiosarcoma by a factor of 1.6 • triples the risk of hypothyroidism • increases the risk of progressive geriatric cognitive impairment • triples the risk of obesity, a common health problem in
dogs with many associated health problems • quadruples the small risk (< 0.6 %) of prostate cancer • doubles the small risk (5; this is a common cancer and major cause of death in some breeds • triples the risk of hypothyroidism • increases the risk of obesity by a factor of 1.6 - 2, a common health problem in
dogs with many associated health problems • causes urinary «spay incontinence» in 4 - 20 % of female
dogs • increases the risk of persistent or recurring urinary tract infections by a factor of 3 - 4 • increases the risk of recessed vulva, vaginal dermatitis, and vaginitis, especially
for female
dogs spayed before puberty • doubles the small risk (< 1 %) of urinary tract tumors • increases the risk of orthopedic disorders • increases the risk of adverse reactions to vaccinations One thing is clear — much of the spay / neuter information that is available to the public is unbalanced and contains claims that are exaggerated or unsupported by evidence.
Among the malignant splenic cases, the percentage of
dogs with hemangiosarcoma was also higher
for large
dogs (65 %) than small
dogs (46 %)(the picture shows splenic
hemangiosarcoma in a Skipperke).
A more recent publication from U.C. Davis (de la Riva, Hart et al, 2013) looked at two joint disorders and three cancers — hip dysplasia, cranial cruciate ligament tear, lymphosarcoma,
hemangiosarcoma and mast cell tumor — and showed that,
for all five diseases analyzed, the disease rates were significantly higher in both males and females that were neutered either early or late compared
with intact (non-neutered)
dogs.
Dogs with any cancer (except
hemangiosarcoma and mast cell tumor) might be eligible
for a clinical trial to define the optimal dose and schedule
for an oncolytic virus treatment (VSV - IFNβ - NIS).