Sentences with phrase «for drug development»

Once identified, they may be valuable targets for drug development.

The mutation would also serve as a strong candidate for drug development.

It will make these cells available to other researchers, and use them within the project to develop new tools for drug development.

In the process, they've revealed dozens of new leads for drug development.

The company has over 90 partners and licensees for its drug development platforms.

This group of about 800 receptors plays a central role in transferring signals from the environment into the cell and is of great interest for drug development.

The model assumes 13 years for the development of an individual drug, including clinical trials, and estimates the success rates for drug development.

The researchers were recognized for their groundbreaking work involving G - protein - coupled receptors which has provided an important framework for drug development.

The method is an efficient alternative to experimental screening and can hence reduce the time and costs for drug development.

They certainly still have more cash than they need for drug development, especially given the layoffs coming.

Such research would boost current methods employed to identify molecular targets for drug development and improve the current understanding of drug design.

Such trials are inevitably costly, and the traditional strategy for drug development suggests one means of undertaking these development expenses is for wellfunded companies to lead the way, motivated by the potential return on investment to be gained from a successful proprietary therapy.

The findings suggest that PHGDH may represent a promising target for drug development for ER - negative breast cancer.

As our Centre for Drug Development celebrates its 25th birthday, we look at how the landscape of drug development has evolved and the impact our unique work is making internationally.

«We have identified a new target for drug development as well as a new way of targeting an existing pathway.

Hermen Overkleeft, Professor of Bio-Organic Synthesis at Leiden University, added: «This work reveals the power of activity - based protein profiling: the probe described here at once enables screening for heparanase inhibitors from large compound collections and is a lead compound for drug development in its own right.

The «mini-tumors» are extremely useful for drug development because they faithfully replicate several features of the original cancer.

The computing power needed to model the complex interaction of biological compounds for drug development was not yet readily available, but that was always in the back of Tehrani's mind.

This is far more targeted than the traditional model for drug development, which includes such scattershot methods as screening natural elements like soil from a plateau in Norway and then asking, What might this do?

The Mast Cells and Basophiles: Targets for Innovative Therapies project, funded by COST funding BM1007 of the EU, brings together European experts focusing on the identification of new target molecules for drug development, including allergy drugs.

Understanding the interplay between circulating lipids and the risk of type 2 diabetes and coronary artery disease (CAD) is of emerging public health importance and has implications for drug development for cardiovascular disease prevention.

Exploration of these findings in the context of human disease genetics provides insights into the role of inherited variation in blood metabolic diversity and identify potential new opportunities for drug development and for understanding disease.

Findings may also lead to a greater understanding of how other organs in the body age, which could pave the way for drug developments in a number of age - related diseases, including cancer.

Howard Lee, director of the University of San Francisco's Washington, D.C. — based Center for Drug Development Science, says that PK / PD modeling has so far been geared mostly toward drug efficacy, but that concern in the US Congress and among the public ensures that safety is going to become more important in the future.

Academic centers pursuing this sort of drug development «would be well advised to consider why companies aren't doing it,» says Carl Peck, director of the Center for Drug Development Science at Georgetown University in Washington, D.C..

The symposium we've convened addresses the ways Organs - on - Chips technology is being used for drug development by pharmaceutical companies and for precision medicine by clinicians.

«Because of that, they are extremely important for drug development.»

Three of these loci are located near genes known to be involved in bone mineral density, and one, 13q14, is close to a gene known as RANKL which is already being used as target for drug development by a major pharmaceutical company.

Identifying the functions of GABAA receptors forms the scientific basis for drug development.

IDEA Pharma has released its 2018 Freshness Index for drug development.

Finally, the bill includes $ 2.23 million «for services and expenses related to the retention of professional football in western New York» and re-obligates $ 22,000 at Stony Brook University originally earmarked for a drug development magnet facility for «stadium improvement and locker room facilities.

«This offers a distinct advantage as a mechanism for drug development.»

«Big pharma has been fairly resilient, with pharmaceutical firms continuing to hire for drug development.

But they do not understand the skill sets that are absolutely critical for drug development.»

«That suggests it might be possible to extend the window in humans by targeting the A1 receptor for drug development,» Zakharenko said.

I learned a great many new skills while on the QA team, from regulatory requirements for drug development to implementing good laboratory practice, including writing and organizing standard operating procedures, as well as performing research audits.

To insiders, telomerase was a much better prospect for drug development than the Werner protein.

So dozens of psychiatrists recently laid out a strong case for drug development, telling FDA officials that practitioners need medicines specifically designed for hotheadedness.

We think it opens up a new avenue of investigation for drug development, guiding surgery, and understanding progression and spreading of cancer,» Kilian said.

Can we compress the process for drug development, evaluation and approval?

«Finding the b - secretase enzyme is a very important development, not only for drug development but also for the clues it will give us about [amyloid] biology,» says John Durkin, a biochemist at Cephalon in West Chester, Pennsylvania.

Being able to see these structures in new ways will help us to understand interactions in the human body and may open new avenues for drug development.»

In a statement, Representative David Obey (D — WI), who chairs both the full appropriations committee and the NIH panel, said the bill would allow NIH to spend up to $ 50 million of its increase on the Cures Acceleration Network (CAN), a program created by the health care reform bill earlier this year that would give out large grants for drug development.

Profiling neurons to define new target proteins for drug development is among the next logical steps in this line of research.

The study of genetic variation between individuals provides a powerful way to understand these mechanisms which underlie disease risk, which in turn will provide a stimulus for drug development.»

Identifying key actors in this circuitry will open the possibilities for drug development.

«More optimized compounds targeting that same reactive lysine in SIN3A might hinder cancer cell growth and malignancy, and thus might represent a starting point for drug development,» said Cravatt.

The experimental therapeutics approach, widely accepted for drug development, is equally relevant to psychosocial treatment development.

This function makes Bcl - xL an intriguing focus for drug development.