Sentences with phrase «for drug use disorder»

Not exact matches

Potential subjects were accepted into the study if they had none of the following conditions: severe or symptomatic cardiac disease or hypertension; history of bleeding disorders; chronic history of gastric, intestinal, liver, pancreatic, or renal disease; any portion of the stomach or the intestine removed (other than an appendectomy); history of intestinal obstruction, malabsorption, or use of antacid drugs; cancer (active or use of medications for a history of cancer treatment within the past 5 y); history of chronic alcoholism; a convulsive disorder; or abnormal results in screening blood or urine samples.

Clenbuterol, a therapeutic drug first developed for people with breathing disorders such as asthma, is widely used by bodybuilders and athletes.

Domperidone is a prescription drug used for decades for gastrointestinal disorders.

The drug, which is officially used to treat gastric disorders, is often used off - label to increase milk supply for nursing mothers.

«Epigenetic alteration a promising new drug target for heroin use disorder.»

89 people from compulsory centres and 95 from voluntary centres who met criteria for an opioid use disorder had drug tests and interviews on study entry and repeatedly after release (at one, three, six, nine or 12 months post-release).

U.S. Health & Human Services Secretary Sylvia Burwell last year proposed a response, calling for a program to change doctors» opioid prescribing practices, to expand the use of naloxone, a drug used to reverse the effects of an opioid overdoses, and increase patient access to medication assisted treatments for opioid use disorders.

These drugs may be used recreationally to purposefully alter one's consciousness (such as coffee, alcohol or cannabis), as entheogens for spiritual purposes (such as the mescaline - containing peyote cactus or psilocybin - containing mushrooms), and also as medication (such as the use of narcotics in controlling pain, stimulants to treat narcolepsy and attention disorders, as well as anti-depressants and anti-psychotics for treating neurological and psychiatric illnesses).

Traditional antipsychotic drugs, which have been used for 40 years, are known to alleviate symptoms of the disorder in some patients by blocking receptors of dopamine, a neurotransmitter that is central to the brain's reward system as well as cognitive processing like attention and problem - solving.

UCLA chemists and molecular biologists have for the first time used a «structure - based» approach to drug design to identify compounds with the potential to delay or treat Alzheimer's disease, and possibly Parkinson's, Lou Gehrig's disease and other degenerative disorders.

Bioengineers from Queen Mary University of London (QMUL) have shown for the first time that lithium chloride, a common drug used to treat mental health disorders, could offer an effective treatment against osteoarthritis by disrupting the length of the cells» antennae called primary cilia.

The report, requested by the U.S. Food and Drug Administration (FDA), says it is possible to stem the still - escalating prevalence of opioid use disorder and other opioid - related harms without foreclosing access to opioids for patients suffering from pain whose providers have prescribed these drugs responsibly.

«Ineffectiveness of «wonder drug» for alcohol use disorders.»

This new combination of electronics and drugs to intervene in an individual brain circuit might be used to create mouse models of other mood disorders for other studies, Dzirasa said.

By combing through tens of thousands of published judicial opinions with the help of 17 law students and three undergraduates, using search terms such as «brain disorder,» «biological,» and «CT scan,» however, Farahany's team found that use of such evidence is growing for a wide range of violations including robbery, fraud, and drug possession.

«Drugs currently used for AUDs (alcohol use disorders)-- acamprosate, naltrexone and disulfiram — have limited success — so this is a ground - breaking development with enormous potential,» said Professor Bartlett who is based at the Translational Research Institute.

After controlling for age, race, sex, marital status, education, drug use, and smoking, compared to people who did not binge drink, people who drank at the various binge levels were much more likely to experience an alcohol - related emergency department visit; have an alcohol use disorder; be injured because of drinking; be arrested or have legal problems resulting from alcohol use; or be the driver in an alcohol - related traffic crash.

Treatment of the mutant mice with lithium — the same drug used by psychiatrists for over half a century to treat patients with severe mood swings in bipolar disorder — normalizes the number of spines (right).

Drug use and behaviour problems were six per cent lower for program participants, arrest rates 19 per cent lower, and diagnoses of mental health disorders 13.5 per cent lower.

Dr Bokhari, a health economist in the School of Economics and ESRC Centre for Competition Policy at UEA, analysed the impact of such agreements on US market prices for drugs used to treat attention deficit hyperactivity disorder (ADHD).

Researchers at Penn Medicine's Center for Studies of Addiction have now found that the drug baclofen, commonly used to prevent spasms in patients with spinal cord injuries and neurological disorders, can help block the impact of the brain's response to «unconscious» drug triggers well before conscious craving occurs.

With an estimated 60,000 drug overdose deaths in 2016 alone, the researchers emphasize the need for the American health care system to embrace medications such as methadone to treat opioid use disorder, provide addiction treatment in primary care clinics and develop non-addictive alternatives for chronic pain.

The current study differs from previous investigations in that — instead of relying only on participants» answers to survey questions about their use of stimulants and other drugs, alcohol consumption and other factors including quality of life — it relied on structured interviews that have been validated for the diagnosis of neuropsychiatric disorders, including substance - use disorders.

Misusers were more likely to meet criteria for substance - use disorder — including use of drugs and alcohol together — and 67 percent actually met or approached criteria for stimulant - use disorder.

Psychostimulant drugs such as Ritalin and Adderall, prescribed to treat attention - deficit hyperactivity disorder, and Aricept, used as a treatment for Alzheimer's disease, have been shown to improve concentration and recall in healthy people, too.

«In addition to higher levels of ADHD, conduct disorder, and alcohol or drug use disorders, the majority of those misusing stimulants met or approached criteria for stimulant - use disorder.»

The attention deficit hyperactivity disorder drug is a popular study aid among US college students, around a third of whom have used prescription stimulants for non-medical reasons.

The researchers have managed to reverse fatty liver disease in mice by treatment with a drug called Tudca, which is currently used for other disorders.

His next project involves investigating ethylphenidate, a drug similar to methylphenidate, the drug used for attention deficit disorder and most commonly known as Ritalin.

The study couldn't tell whether they were misusing prescription amphetamines, such as those used for attention deficit disorder, or using illicit drugs such as methamphetamine.

Methotrexate is already used as a chemotherapy drug for several types of cancer, and this early research shows that at much lower doses it could have the potential to help treat certain blood disorders.»

Rao and her team hope that pinpointing the importance of this trafficking mechanism in autism spectrum disorders may lead to the development of new drugs for autism that alter endosomal pH. As the use of genomic data becomes increasingly commonplace in the future, the step-wise strategy devised by her team can be used to screen gene variants and identify at - risk patients, she says.

The use of selective serotonin - reuptake inhibitors (SSRIs), a class of drugs broadly prescribed for mood disorders as well as for nonpsychiatric conditions, previously has been associated with an increased risk of bone fracture.

They write, «This real - world, almost paradoxical, phenomenon demonstrates the complexity inherent in the treatment of addictive disorders — a medication intended to treat substance use disorder that has its own abuse potential, upon gaining popularity and increased availability, will inevitably be explored by drug abusers for reward and reinforcement purposes.»

Other research has shown that long - term use of cannabis increases adolescent drug users» risk for certain psychiatric and neurological disorders, such as schizophrenia.

A promising glutamatergic drug for the treatment of substance use disorders is N - acetylcysteine (NAC), an amino acid cystine prodrug.

Dr. Vilcek's contributions to the understanding of proteins that control the body's defenses were instrumental in the development of the anti-inflammatory drug Remicade ®, the first member of a new class of therapeutics called TNF blockers that are now widely used for the treatment of Crohn's disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriasis, and other chronic inflammatory disorders.

• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study

But perhaps even more staggering is that, according to different studies, only 10 percent of people with substance use disorders receive any type of treatment for their dependency on alcohol, prescription medications and / or illicit drugs — even if they're patients at a hospital.

Alcohol and Drug Abuse Inpatient Program Short - term inpatient detoxification and treatment for adults with substance use disorders who require a secure environment.

Other drugs that might cause hair loss include methotrexate (used to treat rheumatic conditions and some skin conditions), lithium (for bipolar disorder), nonsteroidal anti-inflammatory drugs (NSAIDs) including ibuprofen, and possibly antidepressants.

For instance, St. John's wort, which is often taken to treat depression and anxiety, affects how the body absorbs dozens of prescription medications and may diminish the efficacy of statins and beta - blockers, a class of drugs used to treat high blood pressure and heart - rhythm disorders.

Hayes noted that lithium has been used for more than half a century to treat bipolar disorder, but it's still not clear how the drug stabilizes a person's mood.

I walked out of his office that day with a prescription for Lexapro — a drug used to treat anxiety and major depressive disorder.

«It gives us hope that perhaps we can use these signatures or hallmarks of the disorder to screen for drugs that can reverse them,» says lead researcher Dan Geschwind.

Requip is also used to treat movement disorders caused by anti-psychotic drugs for mental patients (such as Prolixin and Haldol).

Ketogenic diets that's been around for a while and used to treat drug - resistant seizure disorders in children since the 1920's and more recently has been used to help reduce weight and improve mental focus.

Lithium is still a widely used drug in internal medicine and psychiatry, and has been used for decades as a mood stabilizer for those with bipolar disorder, major depression and suicidal ideation.

Night owls beware, without adequate sleep, you're at higher risk for psychological disorders, diabetes, and stomach and breathing troubles, and are more likely to participate in unhealthy habits like smoking cigarettes, drinking alcohol, and using illegal drugs.

Case reports of mania induction with St John's wort have resulted in limited use of this herbal for the treatment of both major depressive disorder and bipolar disorder.45, 46 Interactions between St John's wort and conventional drugs are mediated by the induction of cytochrome P - 450 3A4, which results in increased metabolism and decreased absorption of widely used drugs, including digoxin, anticoagulants, antiretrovirals, oral contraceptives, statins, and cyclosporine.47