Normal and BCC affected dogs are negative
for the dynamin 1 mutation causing EIC in Labrador Retrievers.
Shnyrova et al. (p. 1433; see the Perspective by Holz) reconstituted dynamin - mediated membrane scission on lipid nanotubes and suggest a molecular model
for dynamin activity that takes into consideration all known aspects of dynamin function.
Not exact matches
Using lipid nanotubes as substrates to directly measure geometric intermediates of the fission pathway, we found that GTP hydrolysis limits
dynamin polymerization into short, metastable collars that are optimal
for fission.
Dynamins are functionally associated with synapses, which are important
for the communication between nerve cells.
The
dynamin - related GTPase Drp1 is required
for embryonic and brain development in mice.
Interchangeable adaptors regulate mitochondrial
dynamin assembly
for membrane scission.