Sentences with phrase «for effectiveness trials»
This document makes a strong case for the need for effectiveness trials and dissemination research to further the advances of prevention science.
http://www.preventionresearch.org/ Not exact matches
Capital punishment's lack of demonstrated superiority as a deterrent (the evidence for its effectiveness being at best mixed), the capacity of society to protect itself equally well by permanently imprisoning those who are currently being executed (which is possible at limited marginal cost, especially when one takes into account the cost of the extended trial procedures and interminable appeals and reviews which usually accompany capital punishment)-- all these points are important, but their utility is chiefly as rebuttal arguments in response to the empirically weak but emotionally strong claims made on behalf of capital punishment.
Although Step 10 of the UNICEF UK Baby Friendly Initiatives requires that accredited maternity units provide post-natal breastfeeding support groups, the availability and uptake of these services remains unclear.40 The effectiveness of peer - support for long - term breastfeeding success has been well documented in middle - income countries, 35,41 and a systematic review has emphasized the importance of skilled post-natal breastfeeding support in the UK.39 However Graffy et al. 40 concluded from a randomized controlled trial of support provided by volunteer breastfeeding counsellors that although such support was rated by mothers as helpful, volunteer support was not effective at increasing breastfeeding duration, perhaps owing to mothers not actively taking up such support.
To determine the cost - effective method of delivery, from society's perspective, in patients who have had a previous cesarean.We completed an incremental cost - effectiveness analysis of a trial of labor relative to cesarean using a computerized model for a hypothetical 30 - year old parturient.
We found no evidence from randomised controlled trials about the effectiveness of breastfeeding education and support for women with twins or higher order multiples, or the most effective way to provide education and support.
The safety, impact and effectiveness of a policy of early discharge for healthy mothers and term infants was assessed in one review that included ten randomised trials (Brown 2007).
A randomised controlled trial of the effectiveness of support from breastfeeding counsellors for women who want to breastfeed
The effectiveness of a Chinese midwives» antenatal clinic service on childbirth outcomes for primipare: A randomised controlled trial
Goodstart: a cluster randomised effectiveness trial of an integrated, community - based package for maternal and newborn care, with prevention of mother - to - child transmission of HIV in a South African township
The clinical effectiveness of different parenting programmes for children with conduct problems: a systematic review of randomised controlled trials
Oneida County Health Department Holds Trial Point - Of - Dispensing Drill (POD) Drill for Distribution of Medication In the Event a Biological Attack On September 1st, 1:00 pm — 2:30 pm (MVCC Jorgensen Athletic Center) the Oneida County Health Department will be conducting a trial Point of Dispensing Exercise to test the Health Department's effectiveness in responding to a biological atTrial Point - Of - Dispensing Drill (POD) Drill for Distribution of Medication In the Event a Biological Attack On September 1st, 1:00 pm — 2:30 pm (MVCC Jorgensen Athletic Center) the Oneida County Health Department will be conducting a trial Point of Dispensing Exercise to test the Health Department's effectiveness in responding to a biological attrial Point of Dispensing Exercise to test the Health Department's effectiveness in responding to a biological attack.
The researchers caution that the booster therapy used in their new study will not be available on the market or even for use in human trials anytime soon; it must await years of animal testing for safety and effectiveness first.
A phase I clinical trial for a Zika vaccine which began in August 2016 in partnership with the Wistar Institute and Inovio / GeneOne Pharmaceuticals aims to discover the safety and effectiveness of a DNA vaccine for Zika.
As promising new therapies such as those directly targeting survivor motor neuron (SMN) are entering clinical trials for infants, children, and adults with SMA, researchers are searching for biomarkers in blood that can monitor their effectiveness.
Their results, published this week in the journal Biomedical Optics Express, from The Optical Society (OSA), may yield a cheaper and less invasive initial screening test for colon cancer that could complement colonoscopy, though further clinical trials will need to demonstrate the safety and effectiveness of the blood test before it is routinely used.
It showed effectiveness against liver cancer in a phase II clinical trial and will move into a phase III trial later this year, David Kirn, an oncologist and the company's president and chief executive officer, said at a recent meeting of the American Society for Gene & Cell Therapy in Washington, D.C..
«If we can confirm selumetinib's effectiveness in treating advanced uveal melanoma in this follow - up trial, it will become the standard therapy for this disease, forming a foundation for new drug combinations that could maximize selumetinib's MEK - inhibitor effect,» he said.
The review focused on U.S. - based trial results on seven approaches used for one or more of five painful conditions — back pain, osteoarthritis, neck pain, fibromyalgia, and severe headaches and migraine — and found promise in the following for safety and effectiveness in treating pain:
Jones added that hope is on the horizon through preclinical trials that are testing several amphetamine - like drugs for effectiveness in treating cocaine addiction.
«This comparative effectiveness clinical trial provides two new treatments for the 50 percent of adults with autism who have average or above intelligence and formal language,» said Minshew, adding that it's now critical that both new treatments be disseminated in the community.
Kipnes is currently recruiting patients for a second safety trial as well as a larger Phase 2 trial of the drug's effectiveness.
The controversy came to a head in March when the National Institutes of Health issued a notice of a competition soliciting participation in a large - scale clinical trial to evaluate the effectiveness of fetal surgery as a treatment for spina bifida.
«While dozens of clinical trials have demonstrated the effectiveness of collaborative care for treating depression in primary care, comparatively few have addressed anxiety, despite their similar prevalence and adverse impact on health - related quality of life and excess utilization of health services,» said Bruce L. Rollman, M.D., M.P.H., professor of medicine and director of Pitt's Center for Behavioral Health and Smart Technology.
The key change is the creation of a new health research regulatory agency, known as the National Institute for Health Research (NIHR), to streamline regulation and improve the cost effectiveness of clinical trials.
«Given the effectiveness of inosine in promoting cortical plasticity, axonal sprouting, and dendritic branching, the present evidence of efficacy after cortical injury in a non-human primate, combined with a long history of safe use, indicates a need for clinical trials with inosine after cortical injury and spinal cord injury,» noted Dr. Moore.
Larger, well - designed studies, such as cluster randomized trials, are ultimately needed to confirm the effectiveness of this strategy,» writes Alice Y. Guh, M.D., M.P.H., and L. Clifford McDonald, M.D., of the Centers for Disease Control and Prevention, Atlanta.
«The data from these two Phase III trials conducted in Europe and in the U.S. support the effectiveness of this novel photo - protective drug, offering the patients in Europe — where the drug has been approved by the European Medicines Agency — the opportunity to perform their daily functions without the pain induced by sun exposure,» said Robert J. Desnick, PhD, MD, Principal Investigator of the U.S. Trials and Dean for Genetic and Genomic Medicine, Icahn School of Medtrials conducted in Europe and in the U.S. support the effectiveness of this novel photo - protective drug, offering the patients in Europe — where the drug has been approved by the European Medicines Agency — the opportunity to perform their daily functions without the pain induced by sun exposure,» said Robert J. Desnick, PhD, MD, Principal Investigator of the U.S. Trials and Dean for Genetic and Genomic Medicine, Icahn School of MedTrials and Dean for Genetic and Genomic Medicine, Icahn School of Medicine.
Vaccine efficacy was set at an average of 60 % (actual numbers depended on the different virus subtypes and on whether a person had been exposed due to a prior natural infection) based on recent phase III trial results for the Sanofi - Pasteur vaccine that had shown moderate effectiveness.
Offsetting any such savings, according to CSDD, are higher costs due to the increased complexity of clinical trials, a greater focus on chronic and degenerative diseases, and tests for insurers seeking comparative drug effectiveness data.
Researchers say larger, longer clinical trials are needed to prove the drug's safety and effectiveness before it can be approved for sale.
«Stroke Care: Randomized penumbra 3 - D trial of next generation stent retriever meets primary endpoints: Data also highlight frontline effectiveness of aspiration using Penumbra System for stroke revascularization.»
Spigelman cautions, however, that larger trials are needed to confirm the effectiveness of both therapies and for them to be approved for global use.
FDA - approved pharmaceuticals for alleviating angina have about a 55 percent effectiveness level in randomized controlled trials; the placebo runs about 45 percent.
The results of the first trial of the effectiveness of a vaccine for dengue, a sometimes fatal disease endemic throughout most tropical countries, have engendered both enthusiasm and disappointment.
Janardan Pandey, Ph.D., an immunogeneticist specializing in immunoglobulin GM genes at the Medical University of South Carolina, helped monitor for immune responses that could limit the effectiveness of the broadly neutralizing antibody VRC01 in a phase 1 trial of that antibody in HIV - infected individuals led by a team at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.
Adam R. Glassman, M.S., of the Jaeb Center for Health Research, Tampa, Fla., and colleagues examined the incremental cost - effectiveness ratios (ICERs) of aflibercept, bevacizumab, and ranibizumab for the treatment of DME with an analysis of efficacy, safety, and resource utilization data at 1 - year follow - up from the Diabetic Retinopathy Clinical Research (DRCR) Network Comparative Effectieffectiveness ratios (ICERs) of aflibercept, bevacizumab, and ranibizumab for the treatment of DME with an analysis of efficacy, safety, and resource utilization data at 1 - year follow - up from the Diabetic Retinopathy Clinical Research (DRCR) Network Comparative EffectivenessEffectiveness Trial.
One - year trial data were used to calculate cost - effectiveness for 1 year for the 3 anti-VEGF agents; mathematical modeling was then used to project 10 - year cost - effectiveness results.
However, in this Phase II clinical trial, designed to prospectively evaluate the safety and effectiveness of ACHT for patients with HIV - related lymphoma, researchers discovered that this population had no greater likelihood of developing these complications compared to those without the virus.
Effectiveness of blood flow restricted exercise compared with standard exercise in patients with recurrent low back pain: study protocol for a randomized controlled trial.
CONCLUSIONS: These results have led to the decision to produce GMP - grade c11 - 1F4 for a Phase I / II clinical trial in patients with primary (AL) amyloidosis where the effectiveness of the reagent could be determined.
Jones added that hope is on the horizon through preclinical trials that are testing several drugs for effectiveness in treating cocaine addiction.
Clinical trials are carefully monitored for safety and effectiveness.
Today the FDA issued a Complete Response Letter regarding PTC Therapeutics» application for ataluren, noting that «an additional adequate and well - controlled clinical trial (s) will be necessary at a minimum to provide substantial evidence of effectiveness.»
Phase II Trials clinical studies conducted to evaluate the effectiveness of the drug for a particular disease or signs or symptoms in patients with the disease or condition under study and to determine the common short - term side effects and risks.
Researchers hope that if the ongoing preliminary studies prove the safety and effectiveness of these drugs for certain treatments, the government will step in to fund larger trials.
Reviews of clinical trials on hypnosis have concluded that the evidence of its effectiveness for smoking cessation is insufficient, but other research shows promise: The preliminary results from a small 2007 study of smokers hospitalized with cardiopulmonary diseases showed that the patients who chose to participate in a hypnotherapy session were more likely to be nonsmokers six months later than patients who chose nicotinereplacement therapy (NRT) alone.
A 2014 double - blind placebo controlled trial assessed the effectiveness and safety of magnesium - sulfate - rich mineral water in 244 adult women with functional constipation; researchers observed a trend in improved number of normal stools for the group receiving magnesium - sulfate mineral water.
Nearly 150 clinical trials are currently under way to determine CBTs effectiveness for conditions ranging from gambling addiction to chronic pain.
Peta's most significant contribution in her research life has been to lead world - first randomized clinical trials investigating the effectiveness of a new and innovative treatment option for food cravings in overweight and obese adults (EFT, Emotional Freedom Techniques or «Tapping»), major depression, smoking and for academic stress ad self esteem concerns in teens.
Comparative effectiveness of plant - based diets for weight loss: a randomized controlled trial of five different diets.