The term «egg» is used differently outside the animal kingdom,
for an egg cell (sometimes called an ovum).
The open structure also allows room
for the egg cells to mature and ovulate, as well as blood vessels to form within the implant enabling the hormones to circulate within the mouse bloodstream and trigger lactation after giving birth.
Not exact matches
After the woman's
eggs have been retrieved through the normal IVF protocol and are ready
for fertilization, the mitochondria taken from her stem
cells are injected into an
egg along with a sperm
cell.
For instance, the
egg -
cell cytoplasm strips off all of the many epigenetic factors which differentiate a genetically restricted donor skin
cell from a totipotent zygote.
RU - 486, which is not
for sale in the U.S., blocks
cells in the uterus from receiving the natural hormone progesterone, the function of which is to prepare the lining of the uterus to receive and sustain a fertilized
egg.
Hartshorne has no patience
for those holding a genetic view of personhood, who claim that the potential represented in a fertilized human
egg cell is equivalent to an actual person.
If we say such
cells have the potential of becoming human life, then Catholics are right to argue that the unjoined sperm and
egg also have a similar potential
for life, and anything that stops them joining (such as a condom or withdrawal) is morally equivalent to abortion.
Philippa Taylor explained why she thought it was an encouraging discovery: «There could be real benefits
for some people, particularly young girls or people who are going through cancer treatment or chemotherapy and that destroys any chance of having their own
eggs and growing
eggs cells so if you can remove ovarian tissue, grow some
egg cells outside the womb and implant them after the treatment then that could be very positive.»
For such a being is, in its body, a multicellular organism, a metazoan — to use the scientific Greek — and the
egg is a single
cell.
For example in the fruit fly the first difference between the front and back end of the
egg is caused by the
cells of the mother's ovary, external to the
egg, that release at the anterior end a specific chemical which then diffuses backwards, giving rise to a chemical gradient of concentration.
For many people, the fear of a class of genetically enhanced people is reason enough not to tinker with the DNA of the human germline —
eggs, sperm, embryos and the
cells that give rise to
eggs and sperm.
Altering DNA in germline
cells — embryos,
eggs, and sperm, or
cells that give rise to them — may be used to cure genetic diseases
for future generations, provided it is done only to correct disease or disability, not to enhance people's health or abilities, a report issued February 14 by the National Academies of Sciences and Medicine recommends.
Asexual whiptails have a special trick
for making spermless reproduction work: The
egg cells in other animals first double their choromosomes once and then divide twice, leaving them as haploid
cells, with half the normal number of genetic material.
Fertile
eggs have been created from mouse skin
cells for the first time, raising the prospect of new fertility treatments and babies with two genetic fathers
Combining an
egg's genetic leftovers with donor
cells may be a way to double the number of
eggs available
for IVF in women whose ovarian reserve is running low
For the first time, researchers have made something resembling a mouse embryo without using an
egg cell, allowing them to probe the early steps of development
The idea is that the mitochondria — cellular energy generators — in young, primitive
cells function much better than those in the mature
eggs collected
for IVF.
The study also found that in addition to its role in determining the sex of somatic
cells, Sxl regulation by m6A is required to initiate germline stem
cell differentiation
for developing
eggs.
She found that the
egg cell expels the two mother centrioles, jettisoning them into the two «polar bodies» that also serve as dumps
for its surplus genetic material.
To investigate how the
egg cell manages to rid itself of such a resilient structure, Joana Pinto, a PhD student in the Lénárt lab, developed fluorescent tags
for mother and daughter centrioles in a starfish
egg cell and recorded the entire process of eliminating them.
Stem
cells capable of forming new
eggs could promise limitless
eggs for IVF treatments, and the rejuvenation of older
eggs
Jonathan Tilly and colleagues at Massachusetts General Hospital in Boston first challenged the idea that mammals are born with a limited supply of
eggs back in 2004, when they found evidence
for ovarian stem
cells in...
«If gdf3 is not supplied to the
egg by the mother, the fertilized
egg can not produce two of the three major types of
cells required
for development,» Burdine said.
In a new study, Murphy, a molecular biologist at Princeton University, showed that long - lived bodily, or somatic,
cells in Caenorhabditis elegans, a one - millimeter nematode commonly used as a model
for aging studies in labs, activate genetic pathways completely separate from those found in long - lived
egg, or oocyte,
cells.
It might be sperm
cells on their way to an
egg, a fleet of bacteria off to stir up trouble in your guts or a flock of birds heading
for their wintering grounds.
Although the bulk of the commercial manufacturing uses cultures of bacteria, such as Escherichia coli or Chinese hamster ovary
cells, a few biotech companies are trying to produce therapeutic proteins in the milk of transgenic mammals (such as GTC Biotherapeutics, which is using goats; PPL Therapeutics, which is using sheep; and BioProtein Technologies, which is working with rabbits), transgenic chicken
eggs (such as Avigenics or Vivalis), or even in transgenic crops (such as ProdiGene or Meristem Therapeutics); but it is early days
for these «pharming» methods.
Using a powerful microscope to observe mouse oocytes as they split, Ellenberg's group found that the spindles assembled into two coherent structures, one
for the future
egg and one
for the future polar body.At first, spindles appeared throughout the
cell in a sort of mesh.
«It's been a debate
for many years, whether there were indeed
cells in the adult ovary capable of forming new
eggs,» says Evelyn Telfer, a reproductive biologist at the University of Edinburgh who wasn't part of the new study.
But these fertilised
eggs never progressed beyond the two -
cell stage, well short of the eight -
cell embryo needed
for re-implantation.
Although biologists have known
for decades that
egg cells provide sperm with a little chemical encouragement to reel them in, the molecular nature of this interaction has remained elusive.
For some reason their
eggs contain the same 44 chromosomes as their body
cells — 22 from the mother and 22 from the father — instead of half, and so the
eggs can grow into gecko hatchlings without first being fertilized by sperm.
For instance,
cells from a man's skin could theoretically be used to create
eggs that are fertilized with a partner's sperm, then nurtured in the womb of a surrogate.
They have made it easy
for anyone with basic molecular biology training to insert, remove, and edit genes in
cells, including sperm,
eggs, and embryos, potentially curing genetic diseases or adding desirable traits.
They then purified messenger RNA — a molecule that plays a key role in the production of proteins — from the
cells in the animals» upper intestines, injected the mRNA into immature
eggs cells, and looked
for changes in iron uptake.
In an advance that could lead to new fertility treatments, researchers have coaxed immature human
egg cells to fully develop in the lab
for the first time.
Some scientists, such as Kevin Eggan at Harvard, were disappointed that NIH didn't open the door to the use of embryos created
for research purposes — including through somatic
cell nuclear transfer (cloning) and parthenogenesis (from an unfertilized
egg).
Even though the reproductive age
for humans is around 15 — 45 years old, the precursor
cells that go on to produce human
eggs or sperm are formed much earlier, when the fertilized
egg grows into a tiny ball of
cells in the mother's womb.
«Adults lack stem
cells for making new
eggs.»
The company uses
cells to grow the virus
for the vaccine and claims that this «shows significant time saving» over traditional production with
eggs.
Stem
cell researchers call them «a major step in the right direction,» although some were disappointed that NIH didn't open the door to the use of embryos created
for research purposes — including through somatic
cell nuclear transfer (cloning) and parthenogenesis (from an unfertilized
egg).
The idea is that, by placing an adult
cell from a diabetic,
for example, into a human
egg cell, the
egg cell could turn back the clock of the adult DNA, or reprogram it, to its initial, pristine state.
The problem, he believes, is that Harvard Stem
Cell Institute researchers, following ethics guidelines, decided not to pay women to donate their
eggs for research.
After nearly a year of recruitment efforts, not a single woman consented to donate her
eggs for stem
cell research.
Paying
for human
eggs, many bioethicists argue, commodifies a human resource; Sandel,
for example, a proponent of both research cloning and embryonic stem
cell research, opposes the idea of financial inducement
for what he calls «human reproductive capacity.»
At the July meeting of the European Society
for Human Reproduction and Embryology in Madrid, scientists were horrified — and transfixed — by two presentations: one that explored adding
cells to developing embryos and another that outlined a process of growing
egg cells from aborted human fetuses.
These
cells need to «forget» their own programmed instructions and create a blank slate
for the blueprint of either a sperm or
egg cell to be laid down.
The process begins when a gene
for a molecule with a potentially toxic function, like a protein - chopping enzyme, is accidentally duplicated, typically during the formation of
egg cells and sperm.
Williams contends that these innovations took hold at least 125 million years ago and made it possible
for early angiosperms to evolve more flexible and sheltered modes of fertilization, including ovaries containing
egg cells deep inside the plant.
Although the researchers had first removed the DNA of both the
egg and the fertilizing sperm, the
egg was still primed
for cell division and development, increasing the chances of success, the team says.
Infertility treatments once considered revolutionary are now commonplace: If a man has a low sperm count, sperm
cells can be retrieved from a testicle
for direct injection into an
egg's cytoplasm.