Mitalipov is director of the Center
for Embryonic Cell and Gene Therapy at OHSU.
The guidelines contain provisions for work with induced pluripotent cells that are similar to those in place
for embryonic cell lines.
On Aug. 3, the scientific article in Nature finally gave us some facts about the much - hyped experiments that involved editing the genomes of human embryos at the Center
for Embryonic Cell and Gene Therapy at Oregon Health and Science University.
Once considered mere substitutes
for embryonic cells, re-engineered adult cells are making breakthroughs of their own.
Many scientists agree that the breakthrough could lower the need
for the embryonic cells.
Not exact matches
What do you think of President Obama's decision to increase federal dollars
for embryonic stem
cell research?
Yet the latter form, which is present some eight weeks after fertilization, is not only ethically unacceptable
for research but also far too old to yield
embryonic stem
cells.»
• President Obama did not go half far enough in lifting the ban against federal funding
for embryonic stem -
cell research.
The truth, of course, is that there are no human
embryonic stem -
cell therapies even in clinical trial, let alone ready
for therapy, and there have been no major treatment....
Benedict argued that non-conjugal reproduction such as in vitro fertilization had created «new problems» ¯ the freezing of human embryos,
for instance, and the selective abortion of medically implanted embryos, together with pre-implantation diagnosis,
embryonic stem -
cell research, and attempts at human cloning.
For instance, a strong resolution opposing
embryonic stem
cell research, which destroys human lives, passed with 97 percent support.
research; since most of the reports have concentrated on justifying the creation of cloned human embryos
for research into and treatment of neurodegenerative diseases such as Parkinson's, «stem -
cells» has become synonymous with «
embryonic stem -
cells» in the public imagination.
Just don't try telling me tomorrow you are
for gay rights and
embryonic stem
cell research and we'll both be consistent
Scientists looking
for new methods to make human tissue have successfully used cloning technology to create
embryonic stem
cells from skin
cells.
As specialized
cells are generated during
embryonic development, they are programmed to use only a limited amount of the total genetic information present in the nucleus to produce the proteins required
for their particular function.
Attempts have been made to bridge this divide by proposing alternative sources of
embryonic stem
cells for research and therapeutic purposes.
For most in the scientific community, the debate was never truly about whether adult stem
cells or
embryonic stem
cells would be the most useful therapeutically or whether we could obtain
embryonic - like stem
cells without destroying embryos.
However,
embryonic stem
cells remain the «gold standard,» and studies of all types of stem
cells should continue in parallel
for the foreseeable future.»
Let us be thankful that a tool
for discrediting the pro-life movement (shaming us
for opposing magical cures promised by
embryonic stem -
cell research) has itself been taken out of their hands.
The National Institutes of Health (NIH) has allowed a contract
for the dissemination of
embryonic stem
cell lines approved
for US government funding to lapse, shuttering a key stem
cell bank, and doubling the price researchers pay
for samples of some human
embryonic stem
cell (hESC) line... from $ 500 per vial of frozen
cells to $ 1,000.
(i) a woman's right to an abortion; (iii) medical immunization of teen girls (and boys) against HPV; (iv) assisted suicide; (vi) gay marriage; (vii) my right to view art and theatre deemed «offensive,» «blasphemous» or «obscene» Catholics; (viii) basic $ ex education
for older school children; (ix) treating drug abuse as principally a medical issue; (x) population control; (xi) buying alcohol on a Sunday in many places; (xii) use of condoms and other contraceptives; (xiii)
embryonic stem
cell research; (xiv) little 10 year - old boys joining organizations such as the Boy Scouts of America, regardless of the religious views of their parents; and (xv) gays being allowed to serve openly in the military.
Sullivan went on to suggest that Chaput is using a double standard in the 2008 election by criticizing Catholic supporters of Barack Obama, while turning a blind eye to John McCain's support
for embryonic stem
cell research.
In 2005, before a Congressional hearing in the U.S., Prof. George Q. Daley of Harvard spoke forcefully and influentially about the necessity
for embryonic stem -
cell research to go ahead, and dismissed suggestions that one could work instead with «induced pluripotent stem
cells» («iPS», i.e. stem
cells reprogrammed from some
cells of a living adult).
Yet just such an unlikely resolution may be in hand
for one of the most acrimonious conflicts of recent times: the debate over human
embryonic stem
cells....
Interestingly, none of the opponents of
embryonic stem
cell research have called
for research programs that might increase the odds of embryo survival.
He decreed that the case brought by researchers Drs James Sherley and Theresa Deisher, along with a number of Christian groups including the Christian Medical Association, should be heard; and ordered an injunction temporarily blocking federal funding allocated
for human -
embryonic - stem -
cell research.
The increasing use of in - vitro - fertilisation techniques, and the emergence of new possibilities involving human cloning, mixing of human and animal genetic elements, and the use of
embryonic stem
cells for research, among other things, brought the need
for further teaching.
(In many ways it is worse than when John Edwards said in 2004 that if people voted
for John Kerry, people like Christopher Reeve would get out of their wheelchairs and walk from
embryonic stem
cell therapies.)
President Obama is poised to issue an executive order this week reversing Bush administration limits on federal financing
for embryonic stem -
cell research.
Another possible advantage of using the Dolly method to produce
embryonic stem
cells is that it takes just days, compared with weeks
for iPS
cells.
Not that a principled moral objection shouldn't be enough, but,
for those sitting on the fence, the additional discoveries of alternative sources of
embryonic - type stem
cells should be decisive.
Although he never banned this research outright, President Bush limited federal funding
for research to the
embryonic stem
cell lines that existed before August 2001, thus drawing a line at destroying human embryos created after that date.
For example, ten or twenty years from now, the physician's tools may include embryonic stem cells or products obtained from cloned embryos and fetuses gestated for that purpose, making physicians who provide such treatments complicit in the life destruction required to obtain the modaliti
For example, ten or twenty years from now, the physician's tools may include
embryonic stem
cells or products obtained from cloned embryos and fetuses gestated
for that purpose, making physicians who provide such treatments complicit in the life destruction required to obtain the modaliti
for that purpose, making physicians who provide such treatments complicit in the life destruction required to obtain the modalities.
One of the best talks of this conference was given by Dr. Renee Reijo Pera, Professor and Director of the Center
for Human
Embryonic Stem
Cell Research at Stanford University.
The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA»)
for short, in human
embryonic kidney
cells, brain
cell samples and neurons derived from the stem
cells of healthy people and those with spinal muscular atrophy type I and II.
On March 9, AAAS thanked President Obama
for his executive order on federal support
for human
embryonic stem
cell research and
for his memorandum on scientific integrity.
In SIF - seq, hundreds or thousands of DNA fragments to be tested
for enhancer activity are coupled to a reporter gene and targeted into a single, reproducible site in
embryonic cell genomes.
A type of «virgin birth» stem
cell could be as powerful as
embryonic stem
cells but without the same ethical objections, and are being tested
for Parkinson ’s
Decades after they were discovered, human
embryonic stem
cells are being trialled as a treatment
for two major diseases: heart failure and type 1 diabetes
«We've shown that SIF - seq can be used to identify enhancers active in cardiomyocytes, neural progenitor
cells, and
embryonic stem
cells, and we think that it has the potential to be expanded
for use in a much wider variety of
cell types,» Dickel says.
Faced with an often - hostile Congress, Obama enacted many of his signature policies by executive order — from reversing restrictions on research with human
embryonic stem
cells to helping communities prepare
for climate change.
For example, a consortium of research groups called the London Project to Cure Blindness aims to test RPE transplants from
embryonic stem
cells in patients with macular degeneration this year.
15
For organs to form during
embryonic development, some
cells must commit suicide.
The year's most prominent science issue, federal support of
embryonic stem
cell research, is so controversial that the sons of Ronald Reagan gave dueling speeches at the opposing party conventions; Michael Reagan backs President George W. Bush's policies, including the ban on funding
for research on new stem
cell lines, while Ron supports Senator John Kerry's promise to lift restrictions.
He worries that the ruling could foster an unwelcoming climate that would eventually trickle down to limit funding
for basic research on
embryonic stem
cells.
Scientists believe that
embryonic stem
cells could also be useful
for treating neurodegenerative diseases and diabetes, among other conditions.
The study results were found using mouse
embryonic stem
cells, which are good
cell models
for the study of processes seen in human stem
cells.
For the first time, specialised
cells have been reprogrammed into the equivalent of
embryonic stem
cells without using genes that might trigger cancer.
In granting an injunction to two scientists who oppose widening US government funding
for research on human
embryonic stem
cells (hESCs), Judge Royce Lamberth wrote of «simply preserving the status quo».
Oliver Brüstle, director of the Institute of Reconstructive Neurobiology at the University of Bonn, Germany, who had a patent on a method
for generating neurons from human
embryonic stem
cells rejected by the court, called the ruling «the worst possible outcome», and «a disaster
for Europe».