Sentences with phrase «for embryonic development»

Basement membranes are thin sheets of self - assembled extracellular matrices that are essential for embryonic development and for the homeostasis of adult tissues.

Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors.

PTBP1 is required for embryonic development before gastrulation.

Now, scientists at the Technische Universität München (TUM) have characterized a small heat shock protein responsible for embryonic development in the Caenorhabditis elegans nematode.

Later he found that TCF - 1 is part of the larger Wnt family of signaling molecules that's important not only for immune responses, but also for embryonic development and tissue repair.

Further investigation, says Resar, showed that these unusual properties arise from the ability of HMGA1 to turn on several genes involved in the Wnt pathway, a network of proteins necessary for embryonic development and stem cell activity.

«Genetic instructions from mom set the pattern for embryonic development.»

The huntingtin gene is essential for embryonic development, and scientists have already shown that if mouse embryos don't have it at conception, they die in utero.

Not exact matches

As specialized cells are generated during embryonic development, they are programmed to use only a limited amount of the total genetic information present in the nucleus to produce the proteins required for their particular function.

Some researchers have proposed deleting or disabling key genes that are required for early embryonic development.

Because the possibility of «twinning» exists for that long in the first stages of embryonic development, one could argue that no individual human being can yet be present - and that, hence, experimentation should be permitted.

«BPA and BPS (substitute for BPA) affect embryonic brain development in zebrafish: Low levels of chemicals linked to hyperactivity.»

The decision whether the maternal or the paternal version is shut down occurs early in embryonic development — one reason, why for long it was thought that the pattern of active alleles is nearly homogeneous in the various tissues of the organism.

15 For organs to form during embryonic development, some cells must commit suicide.

For this study, Guttridge, first author David J. Wang, who developed many of the study's concepts, and their colleagues monitored NF - kB activity during tumor development using mouse embryonic fibroblasts and two mouse models.

Their Kupffer's vesicles were abnormally symmetric in shape, and southpaw expression was greatly reduced, suggesting that gdf3 is also required for optimal Nodal signaling during later stages of embryonic development.

We have found that there are many well - preserved cell processes in the two species, for example, in embryonic development.

A new study indicates an essential role for a maternally inherited gene in embryonic development.

Scientists have focused for decades on the role of biochemical cues in embryonic development, Campàs said, because no techniques existed to measure the mechanical cues that cells are exposed to during the formation of tissues and organs.

«It's an exciting development, and we await the outcome over the next year to see how well these cells integrate, and if there are any potential adverse reactions,» says Mike Cheetham of the Institute of Ophthalmology at University College London, one site where research is under way into a human embryonic stem - cell treatment for AMD.

For years, Scripps neuroscientist Jerold Chun had been studying the embryonic brain and how certain lipids in the blood of both the mother and the embryo affect its development.

Study shows memories formed by the same gene - silencing tool used in embryonic development; a finding could set the stage for new therapies for schizophrenia

EMT is crucial for normal embryonic development, but also operates in wound healing, and when abnormally switched on, can enable the spread of tumor cells.

Mainstream biology has followed in Morgan's wake, focusing on animals suitable for studying genetic and embryonic development.

Those deletions tended to involve genes that affect cilia, cellular structures that are important for signaling and patterning in embryonic development.

The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.

«For example, in the embryonic development of plant cells.

All stem cells are immature cells known for their ability to multiply indefinitely and give rise to progenitor cells that mature into specific cell types that populate the body's tissues during embryonic development.

This program normally shuts off after embryonic development, but occasionally — for reasons not yet known — crestin and other genes in the program turn back on in certain cells.

If damage occurs during embryonic development, for example, due to a mutation or environmental influences, repair mechanisms ensure that the animal later appears healthy.

Last December, for instance, Chien's group reported finding markers for heart muscle stem cells by tracing their development from embryonic tissue.

Their embryonic development is pretty normal — except for a bent great toe.

Experts say the new method, reported in the current issue of Cell, could also be a useful tool for studying embryonic development.

«We now have a simple tool for identifying and sorting the cells, which benefits future stem cell research and basic research on early embryonic development.»

«For several years, we have been studying myogenesis, a process by which muscles are formed during embryonic development,» says Jean - François Côté, PhD, Director of the Cytoskeletal Organization and Cell Migration research unit at the IRCM.

This discovery by the scientists at the CRG provides an insight into stem cell - forming molecular mechanisms, and is therefore of great interest for studies on the early stages of life, during embryonic development.

Salk scientists and colleagues have proposed new molecular criteria for judging just how close any line of laboratory - generated stem cells comes to mimicking embryonic cells seen in the very earliest stages of human development, known as naïve stem cells.

During embryonic development individual cells and cell clusters can move over relatively long distances, and cell migration is also essential for wound healing and many immunological processes in adult animals.

They tried hundreds of different recipes; eventually they discovered that if they mixed liver precursor cells (derived from iPS cells) with two other types of standard human cell lines known to be important for embryonic liver development, then the cells would spontaneously form a 4 to 5 - millimeter 3D structure called a liver bud.

The zebrafish is used as a model organism for research into the embryonic development of vertebrates.

These are essential for supporting embryonic and fetal development, and many pregnancies fail because of problems with these tissues.

Both fish and land animals possess clusters of Hoxa and Hoxd genes, which are necessary for both fin and limb formation during embryonic development.

Rivolta and his colleagues knew that during embryonic development, a handful of proteins, including fibroblast growth factor (FGF) 3 and 10, are required for ears to form.

Details of an organism's embryonic development often reveal traits carried by its evolutionary ancestors; consider, for instance, how human embryos initially develop gill - like slits and a tail.

Seeking fresh sources, they looked for cells that express the gene neurogenin 3, a potential sign of cell differentiation because it is the first gene to only switch on in pancreatic islets during embryonic development.

Now, with more ways to monitor gene activity during development — and fully sequenced genomes of various snakes and other reptiles for comparison — Cohn and graduate student Francisca Leal have tracked the genetic activity in embryonic pythons to see why their legs start, but never finish, developing.

Other potential uses of embryonic stem cells include investigation of early human development, study of genetic disease and as in vitro systems for toxicology testing.

Cook's illustrious subjects include the umbrella - bearing British cosmologist Sir Martin Rees of the University of Cambridge, the wrinkle - faced late naturalist and flea expert Miriam Rothschild, and the biologist Christiane Nüsslein - Volhard (left) of the Max Planck Institute for Developmental Biology in Tübingen, Germany, who won the 1995 Nobel Prize in Physiology or Medicine for codiscovering key genes that shape embryonic development.

Because polar bodies are dispensable for human embryonic development, they can be safely removed without harming the embryo.

The researchers used this live - imaging technique to study fly embryos at a key stage in their development, approximately two hours after the onset of embryonic life where the genes undergo fast and furious transcription for about one hour.