Not exact matches
The study, which followed four individuals
for a year after they were treated with
embryonic stem cell - derived retinal pigment epithelial cells
for macular degeneration, observed no serious side effects (tumor
growth or other unexpected effects) related to the therapy.
Heidelberg Neuroscientists have identified a critical regulator
for blood vessel
growth in the developing
embryonic spinal cord.
Rivolta and his colleagues knew that during
embryonic development, a handful of proteins, including fibroblast
growth factor (FGF) 3 and 10, are required
for ears to form.
Expanding from their previous studies with mice, the researchers first established that under specific conditions, culturing human
embryonic stem cells with fibroblast
growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of markers
for the cerebellar plate neuroepithelium — the part of the developing nervous system specific
for the cerebellum — within five.
«We found that IL - 34 is an essential
growth factor
for the differentiation of Langerhans cells and microglia during
embryonic development,» says senior author Marco Colonna, MD, professor of medicine and of pathology and immunology.
Researchers have identified genes that play a role in the condition, some of which are essential
for cerebral cortex
growth during
embryonic development.
This finding complements previous research from the University of Edinburgh and the National Institute
for Medical Research which showed that
embryonic stem cells can be coaxed into this spinal cord cells; however, the Cambridge researchers showed that the in the embryo - like aggregates, the structural organization is more robust and allows
for the polarised
growth of the tissue.
(6) Moreover, subcutaneous adipose of prematurely - aged transgenic mice exhibited high levels of staining
for the senescence marker senescence - associated - β - galactosidase (SAβ - gal) and expressed high levels of several established markers of senescence, including p21, p19, interleukin - 6, (insulin - like
growth factor binding protein - 2 (Igfbp2), and Pai - 1; primary BubR1H / H; INK - ATTAC mouse
embryonic fibroblasts forced artificially into senescence by oncogenic Ras or serial passage exhibited a subpopulation that was both GFP + and stained positively SAβ - gal.
hESC lines I6 and H9 were maintained on Matrigel (BD Biosciences, Bedford, MA; http://www.bdbiosciences.com) coated dishes in medium (comprised of Dulbecco's Modified Eagle's Medium / Ham's F12 supplemented with 20 % knockout serum replacement (KSR), 2 mM non-essential amino acids, 4 mM L - glutamine, 0.1 mM β - mercaptoethanol, 50 µg / ml Penn - Strep, and 4 ng / ml of basic fibroblast
growth factor) conditioned with mouse
embryonic fibroblasts
for 24 hours as previously described [9], [10].
Professor Elly Tanaka and her research group at the DFG Research Center
for Regenerative Therapies Dresden — Cluster of Excellence at the TU Dresden (CRTD) demonstrated
for the first time the in vitro
growth of a piece of spinal cord in three dimensions from mouse
embryonic stem cells.
It's also vital
for normal
embryonic growth, which makes it an important nutrient in pregnancy.
* The role of the US in global efforts to address pollutants that are broadly dispersed across national borders, such as greenhouse gasses, persistent organic pollutants, ozone, etc...; * How they view a president's ability to influence national science policy in a way that will persist beyond their term (s), as would be necessary
for example to address global climate change or enhancement of science education nationwide; * Their perspective on the relative roles that scientific knowledge, ethics, economics, and faith should play in resolving debates over
embryonic stem cell research, evolution education, human population
growth, etc... * What specific steps they would take to prevent the introduction of political or economic bias in the dissemination and use of scientific knowledge; * (and many more...)