Sentences with phrase «for endocytosis»

Recently, he has been focusing on the regulation of a family of yeast purine - cytosine permeases, including the transcriptional controls over their expression, and how, after these proteins bind to their cargo, they are targeted by the ubiquitin system for endocytosis and delivery to the vacuole.

Using state - of - the - art techniques, researchers of VIB, Ghent University and the Max - Planck - Institute in Potsdam - Golm have now identified an adaptor protein complex which is essential for endocytosis and which only exists in plants.

«Plants recycle, too: Biologists have now identified a new protein complex which is crucial for endocytosis in plants.»

β - Arrestins are required for endocytosis of Smo and signaling to Gli transcription factors.

Not exact matches

These findings provide a previously unrecognized mechanism for receptor recruitment of β - arrestin and demonstrate that Dvl plays an important role in the endocytosis of frizzled, as well as in promoting signaling.

The TPLATE complex turned out to be key for plant endocytosis as it arrives first at the position where endocytosis should get initiated.

While proteins involved in endocytosis, such as clathrin, are conserved across the animal and plant kingdoms, the members of the TPLATE complex appears specially designed for plants.

The latest frontier in this search for cancer telltales is the cellular process of endocytosis, which is the way cells take outside materials like proteins inside.

Cell biologists have studied for decades how endocytosis works however up till now they have found it impossible to control the process.

This study reports for the first time the occurrence of collective dynamics of endocytosis and shows how this regulates the onset of cortical actin waves.

Researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) have found that the protein hinders a key step involved in the transmission of neuronal signals, which is essential for higher - brain functioning: vesicle endocytosis at the nerve terminal.

For example, induced endocytosis can be shown to be an optimal solution for transmitting high - fidelity information by signaling receptoFor example, induced endocytosis can be shown to be an optimal solution for transmitting high - fidelity information by signaling receptofor transmitting high - fidelity information by signaling receptors.

High advanced glycation end - products overwhelm innate defenses of enzymes and receptor - mediated endocytosis and promote cell damage via the pro-inflammatory and pro-oxidant receptor for advanced glycation end - products.

Methods: Researchers Harish Shankaran, Haluk Resat and Wiley paired a new module - based systems theory approach with quantitative metrics for network function to show that receptor / ligand properties such as endocytosis can be described by just a few control parameters.

Clathrin is Important for Normal Actin Dynamics and Progression of Sla2p - Containing Patches During Endocytosis in Yeast.

Comparative binding, endocytosis, and biodistribution of antibodies and antibody - coated carriers for targeted delivery of lysosomal enzymes to ICAM - 1 versus transferrin receptor.

Regulation of clathrin adaptor function in endocytosis: novel role for the SAM domain.

The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin - dependent endocytosis.

Applications of pHluorin for Quantitative, Kinetic and High - throughput Analysis of Endocytosis in Budding Yeast.

Flotillins regulate membrane mobility of the dopamine transporter but are not required for its protein kinase C dependent endocytosis.

Endocytosis is not required for the selective lipid uptake mediated by murine SR - BI.

We have shown that the ubiquitous clathrin heavy chain (CHC), well characterized for its role in intracellular membrane traffic and endocytosis from the plasma membrane (PM), forms large plaques connected to α - actinin and actin filaments.

Platelet - activating factor - induced clathrin - mediated endocytosis requires β - arrestin - 1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation.

Endocytosis is the process in which a part of a cell engulfs external molecules for further processing.

We have established that clathrin - dependent endocytosis of the type - I interferon (IFN - α / β) receptor (IFNAR) is required for JAK / STAT signalling.

Endosomes are the main organelles for sorting material that has been taken up from the exterior of the cell by the plasma membrane (endocytosis).

The Johannes group has made two major contributions in this context: the discovery of a membrane trafficking interface between early endosomes and the Golgi apparatus, and the demonstration that dynamic protein - induced glycosphingolipid reorganization acts as a driving force for membrane invagination in clathrin - independent endocytosis.

Our contributions to this field have helped to change the way endocytosis is perceived, from being simply a mechanism for signal attenuation to being a vital component of the cell signalling machinery that provides spatial and temporal dimensions to signalling events (1).

Endocytosis has traditionally been viewed as a mechanism for achieving signal attenuation: activated cell surface receptors are internalised and trafficked through endocytic vesicles to lysosomes, where they are degraded.

At the basic level, this work opened the field of receptor - mediated endocytosis, and at the clinical level it helped lay the conceptual groundwork for development of drugs called statins that lower blood LDL - cholesterol and prevent heart attacks.