Derivation of pluripotent stem cells, either of embryonic origin or following genetic reprogramming, has opened the path for an alternative source
for epidermal cell therapy as these cells are both immortal and pluripotent, theoretically capable of providing any requested number of cells of any desired phenotype.
For epidermal cells, the last cell before the hair cell was the one measured as lmax.
Not exact matches
Multiplexed genetic screening
for epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) gene rearrangements and subsequent biomarker - guided treatment is cost - effective compared with standard chemotherapy treatment without any molecular testing in the metastatic non-small
cell lung cancer (NSCLC) setting in the United States.
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are the preferred treatment option
for patients with advanced non-small
cell lung cancer (NSCLC) who have mutations in the EGFR gene.
The study, called «Molecular Determinants of Drug - Specific Sensitivity
for Epidermal Growth Factor Receptor (EGFR) Exon 19 and 20 Mutants in Non-Small
Cell Lung Cancer,» and published online in the journal Oncotarget, demonstrates how computer modeling of EGFR mutations found in lung cancer can elucidate their molecular mechanism of action and consequently optimize the selection of therapeutic agents to treat patients.
For years researchers have been developing molecular imaging techniques that visualize hormonally active breast cancer cells — specifically those testing positive for human epidermal growth factor receptor 2 (HER
For years researchers have been developing molecular imaging techniques that visualize hormonally active breast cancer
cells — specifically those testing positive
for human epidermal growth factor receptor 2 (HER
for human
epidermal growth factor receptor 2 (HER2).
Human epidermis has been produced in vitro
for decades using adult
epidermal stem
cells from donors to provide
cell therapy.
With this technology, they could watch
for responses as cancer
cells responded to signals from EGFR (
epidermal growth factor receptor).
Title: Capturing
epidermal stemness
for regenerative medicine Authors: Barrandon Y, Grasset N, Zaffalon A, Claudinot S, Lathion Droz - Georget S, Nanba D, Rochat A Date: 2012 Publication Details: Seminars in
Cell & Developmental Biology 2012 Oct 2.
Current studies focus mainly on two receptor systems - the mast
cell surface receptor, FcεRI, and the receptor
for epidermal growth factor that operate in immunological and
cell proliferation responses.
Morphologically, the DZ in the wild type (WT) is marked by the appearance of
epidermal root hairs on the external surface of outer
cell files (trichoblast) and the existence of fully differentiated xylem
for internal
cell files (Dolan et al, 1993; Ishikawa & Evans, 1995; Beemster et al, 2003; Verbelen et al, 2006; Zhang et al, 2010; Mähönen et al, 2014).
The human
epidermal growth factor receptor - 2 (HER2) gene makes proteins responsible
for maintaining healthy
cell growth, division and repair of breast tissue.
Many women are «triple negative» No one yet knows precisely why, but African - American women are roughly twice as likely as white women to have triple - negative breast cancer — so called because tumor
cells in this particularly aggressive form of the disease test negative
for estrogen receptor (ER), progesterone receptor (PR), and human
epidermal growth factor receptor 2 (HER - 2).
Excessive activation of lymphocytes (a form of white blood
cells) are thought to be responsible
for the short
epidermal cell cycle that results in hyperproliferation of skin tissues.
Together with potassium and sterolins, these nutrients encourage
epidermal cell turnover, making the oil ideal
for anti-aging products, dry skin formulations and as a treatment
for damaged skin
cells and a range of skin conditions that include eczema and psoriasis.