Sentences with phrase «for epigenetic marks»

The relationship held: Of the 78 genes the researchers examined for epigenetic marks, only the methylation of the RXRα gene showed a strong relationship with obesity.

Not exact matches

For a plant to create reproductive cells, it must first erase a key code, a series of tags attached to DNA across the genome known as epigenetic marks.

All animals use the same enzyme to create the same methylation mark as a signal for gene repression, and her colleagues who study epigenetics in mice and humans are excited about the new findings, Strome said.

For example, epigenetic reprogramming, a process of erasing and remodeling epigenetic marks, is essential for sperm maturation and represents a critical window of susceptibility to environmentally - induced epigenetic errors that, in turn, may influence reproductive health.&raqFor example, epigenetic reprogramming, a process of erasing and remodeling epigenetic marks, is essential for sperm maturation and represents a critical window of susceptibility to environmentally - induced epigenetic errors that, in turn, may influence reproductive health.&raqfor sperm maturation and represents a critical window of susceptibility to environmentally - induced epigenetic errors that, in turn, may influence reproductive health.»

«Epigenetic factors are like the punctuation marks on the DNA that enables the cell to read and comprehend it correctly for the functioning of the cell,» Blewitt said.

In order to lay down the proper pattern of epigenetic marks, for example, embryos need to get the raw ingredients from their mothers.

The specific pattern of epigenetic marks in a cell type specifies identity and this epigenetic control is vital to what makes our cells different, for example a skin cell from a liver cell, when they all contain the same genetic instructions.

So this reverses the symptoms and it also reverses the biological reasons, the biological cause for the symptoms in the progeny which are the epigenetic marks.

Because every cell in an organism contains the same DNA, epigenetic marks help it find the right form for the type of cell it inhabits.

Researchers based at Rice's Center for Theoretical Biological Physics (CTBP) have constructed computer models to analyze epigenetic marks, which include proteins bound to DNA as well as chemical modifications to histone proteins.

Drugs that inhibit or stabilize epigenetic marks are in clinical use for cancer and are being tested for other indications like sickle cell disease.

For example, epigenetic marks, the proteins and other molecules attached to DNA, are receiving more attention, especially for their apparent role in herediFor example, epigenetic marks, the proteins and other molecules attached to DNA, are receiving more attention, especially for their apparent role in heredifor their apparent role in heredity.

We focus on the 5hmC epigenetic modification and have a patent protected platform for detection of highly accurate signatures for a variety of diseases using this mark.

These 45 variants are significantly enriched for protein - coding changes (n = 13), direct disruption of transcription - factor binding sites (n = 3), and tissue - specific epigenetic marks (n = 10), with the last category showing enrichment in specific immune cells among associations stronger in Crohn's disease and in gut mucosa among associations stronger in ulcerative colitis.

These bivalent epigenetic marks are thought to prepare their cognate loci for transcription, in a cell that is poised to embark on lineage commitment.

Epigenetic marks, such as the modifications of the histones, are also important for the specialisation of the body's cells.