Sentences with phrase «for epithelial»

Some reports suggested a predisposition among Pointers for epithelial tumors.

These live microorganisms have proven health benefits and well - established safety, and have been tested for epithelial cell adhesion and / or resistance to low pH.

Zhang is committed to finding a cure for epithelial ovarian cancer, the most lethal gynecological malignancy in the developed world.

ARHGAP21 Protein, a New Partner of α - Tubulin Involved in Cell - Cell Adhesion Formation and Essential for Epithelial - Mesenchymal Transition.

In the new study, DrugPredict suggested non-steroidal anti-inflammatory drugs, also known as NSAIDs, could have applications for epithelial ovarian cancer.

Barbieri's team re-engineered the cutting section of BoNT molecules, installing an amino acid that has an affinity for epithelial SNAREs.

Not exact matches

Vitamin A also maintains epithelial cells, which are responsible for keeping body surfaces healthy so that they can act as barriers to infection.

The strict definition of celiac disease — positive antibodies to gliadin, intestinal endomysium, and tissue transglutaminase, together with the presence of HLA - DQ2 or HLA - DQ8 genes and an intestinal biopsy that shows at least 20 - 25 CD3 cells per 100 epithelial cells — will account for about 75 - 80 % of all those sensitive to gluten.

Vit A is required for normal vision, for maintaining the integrity and normal functioning of glandular and epithelial tissue, for skeletal growth, for maintenance of immunity, and for protection against certain cancers such as bronchial cancer.

The use of hydrogels dressings is a concept stolen from disciplines such as geriatrics, where patients suffer bed wounds and these water - based polymer matrix dressings are applied to maintain moisture, inhibit scab or crust formation, reduce pain, and enhance epithelial migration for wound repair.

Secretion of the hormones estrogen and progesterone set the stage for dramatic changes that take place in the breast during pregnancy: a massive proliferation of mammary epithelial cells, and the formation of thousands of ductal structures, which support milk production and transport during lactation.

While abnormal immune responses are largely responsible for these diseases, issues relating to gut microbiome, intestinal epithelial cells, immune components and the gut's rhythmic peristalsis motions can also contribute to and exacerbate symptoms.

He determined that epithelial cells lining the brain's blood vessel walls contain a surface protein, or receptor, that can snag insulin, the hormone essential for metabolizing carbohydrates and fats.

Efficient repair of the epithelial barrier is critical for suppressing inflammation and reestablishing intestinal homeostasis.

Researchers showed that flu infection changed the metabolism of human lung epithelial cells, the prime location for replication of flu virus.

Part of the cytoskeleton, vimentin gives flexibility and structure to the cell, but it is also a marker of epithelial - mesenchymal transition (EMT), which is considered a crucial event for metastasis in epithelial tumors.

In those cells the Esrp1 and Esrp2 proteins enforce epithelial - specific splicing isoforms for hundreds of different genes, as Carstens and his team have shown in studies since 2009.

People infected with HIV have few signs of microbial translocation during the first six months of infection as it takes time for the virus to kill off epithelial cells and weaken the gut wall so that bacteria can leak through — so treating them early could be more effective.

The study, which followed four individuals for a year after they were treated with embryonic stem cell - derived retinal pigment epithelial cells for macular degeneration, observed no serious side effects (tumor growth or other unexpected effects) related to the therapy.

Yang et al. report on one such strategy: Taking the knowledge that an increase in type I interferons (IFNs) correlates positively with clinical outcome in several cancers and that type I IFNs can enhance antitumor immunity in some models, the authors tethered IFN - β to a monoclonal antibody targeting the epithelial growth factor receptor (EGFR), which is approved for use in treating metastatic colorectal cancer and head and neck cancer.

Recently published in the journal eLife and featured in a poster session at this year's American Association for Cancer Research (AACR) annual meeting, preclinical experiments show for the first time that PLK1 promotes the migration of prostate cancer cells by setting in motion a process that induces what is known as the epithelial - to - mesenchymal transition (EMT).

«The first thing that needs to happen for wound healing is to activate the migration of epithelial cells,» Oudhoff says.

A total of 640 women in the MMS group had surgery for suspected cancer, of whom 133 women had invasive epithelial ovarian cancers (iEOC).

Researchers at the RIKEN Center for Developmental Biology in Kobe plan to generate replacement retinal pigment epithelial cells from iPS cells generated from patients suffering age - related macular degeneration.

The images show how a growth factor caused cells to change forms and regroup from tight packs of epithelial cells to more mobile, loose arrays of mesenchymal cells — information useful for studying cancer and wound healing.

«Two components of the pathway, the phosphatase PTPD2 and the lipid PA, are together required for HER2 signaling to function in mammary epithelial cells.»

Similar patches have already had some positive results for the «wet» form, in which blood vessels invade and destroy the retinal pigment epithelial cells.

The resulting organoids could either be banked for future use or immediately fragmented and seeded into the «epithelial» channels of multiple Organ Chips where they were further matured by flowing specialized culture medium and applying mechanical stimulation to the channels to mimic physiological peristalsis - like motions.

To test their idea for the dry form, Amir Kashani of the University of Southern California in Los Angeles and his colleagues coated 6 by 4 - millimetre slithers of polymer with retinal pigment epithelial cells they had grown, then transplanted these into four people.

It has been designed for treating the «dry» form of macular degeneration, caused by deposits on the retina gradually killing retinal pigment epithelial cells, which support light - capturing cells.

With each breath, for example, epithelial tubes transport oxygen to the lungs.

Problems in epithelial tube contractility are responsible for asthma, raised blood pressure and gastrointestinal disorders.

As an important prerequisite for tube formation, epithelial cells become asymmetric or «polar», acquiring structurally and functionally distinct ends or surfaces.

«It is an important physiological mechanism for the ordered removal of cells from the epithelial layer, but when it is out of control has profoundly damaging effects,» said Campos.

Factors such as gender, smoking, asbestos exposure and disease stage did not have an effect on whether patient's disease was positive for PD - L1 expression, but researchers did find that expression of the protein was more common in non-epithelial tumours compared to epithelial tumours.

During pregnancy, the elevated blood estrogen level induces the proliferation of mammary epithelial cells, leading to the development of the mammary gland in preparation for lactation.

Xiaowei «George» Xu, MD, PhD, associate professor of Pathology and Laboratory Medicine and Dermatology at the Perelman School of Medicine, University of Pennsylvania, and colleagues published in Nature Communications a method for converting adult cells into epithelial stem cells (EpSCs), the first time anyone has achieved this in either humans or mice.

August 2, 2006 Jeffrey Matthews appointed chairman of surgery at the University of Chicago Gastrointestinal surgeon Jeffrey Matthews, MD, a leading authority on the surgical treatment of diseases of the pancreas, bile ducts and liver, and a prominent scientist known for his fundamental research on defects in chloride transport in epithelial tissue, has been appointed chairman of surgery at the University of Chicago, effective October 1, 2006.

Progression of chronic kidney disease associated with progressive fibrosis and impaired tubular epithelial regeneration is still an unmet biomedical challenge, because once chronic lesions have manifested, no effective therapies are available as of yet for clinical use.

In addition to his studies of epithelial polarity, Dr. Goldenring also studies the mechanisms responsible for the development of pre-neoplastic lineages from metaplasias in the stomach and their roles in gastric carcinogenesis.

His recent published work describes the rescued visual function in animals using retinal pigment epithelial cells derived from human embryonic stem cells and a method for deriving stem cells using a single - cell approach that does not harm embryos.

First, the MimEX ™ Cell Plating Procedure is used to maintain a uniform irradiated fibroblast monolayer for the rapid clonal expansion and efficient differentiation of tissue - specific adult epithelial stem cells.

Publication: A bioengineered retinal pigment epithelial monolayer for advanced, dry age - related macular degeneration.

Interestingly, the zebrafish assay did not show epithelial enhancer activity for the +105 kb element by itself.

MimEX ™ Tissue Models System provides a platform for the isolation, expansion, and differentiation of adult epithelial stem cells into 3 - D ex vivo organ tissue.

This video provides an overview of MimEX ™ Tissue Model Systems, a next - generation 3 - dimensional (3 - D) cell culture platform for the generation of ex vivo epithelial - derived organ tissue.

A549 lung epithelial cells grown as three - dimensional aggregates: alternative tissue culture model for Pseudomonas aeruginosa pathogenesis.

The inner wall of the small intestine is lined with epithelial tissue covered in wrinkles and folds from which villi — microscopic fingerlike pieces of tissue — project, increasing the surface area for absorption.

Leveraging these technologies, the team generated expression profiles for a total of 53,193 small intestinal epithelial cells.

Using Cultrex ® BME, MimEX ™ Tissue Models System provides a platform for the isolation, expansion, and differentiation of adult epithelial stem cells into 3 - D ex vivo organ tissue.