Sentences with phrase «for eukaryotic»

Sorry to bug you again Paul, but further to what you said about the Modified Ketogenic Diet might be inappropriate for eukaryotic pathogens (fungi, protozoa), is it possible this issue could be offset by the liberal use of MCT oil that inc. lauric acid?

For eukaryotic proteins (excluding plant sequences) an overall prediction accuracy of 66 % for four locations was achieved, with 33 % of the sequences being predicted with an accuracy of 82 % or better.

The technology included a variety of expression systems, including the wheat germ cell free translation system for eukaryotic gene expression, to take synthetic gene sequences and translate them into proteins.

Despite its power, RNAi is amazingly simple to perform in the roundworm C. elegans, an important model system for eukaryotic gene function.

Craig Bingman, Scientist at University of Wisconsin - Madison and collaborator for the Center for Eukaryotic Structural Genomics.

Fox and colleagues applied for a PSI grant in 2000, and on the strength of their science and Wisconsin's structural biology depth, they received funding in 2001 to create the Center for Eukaryotic Structural Genomics.

Our study suggests that the ability to undergo unisexual reproduction may be an evolutionary strategy for eukaryotic microbial pathogens, enabling de novo genotypic and phenotypic plasticity and facilitating rapid adaptation to novel environments.

Not exact matches

Over eons, pieces of mitochondrial DNA have naturally inserted into eukaryotic genomes; at birth, for example, humans have between 755 and 1,155 germline mitochondrial DNA inserts that have been passed on through generations.

AS A species made up of eukaryotic cells complete with mitochondria, nuclei and other complex structures, it's easy for us Homo sapiens to look down on the far simpler prokaryotes, the cells of which lack such structures.

Several eukaryotic chromatin - associated domain proteins were identified, suggesting a eukaryotic - like mechanism for chlamydial nucleoid condensation and decondensation.

Excitingly, these proteins are functionally enriched for membrane bending, vesicular biogenesis, and trafficking activities, suggesting that eukaryotes evolved from an archaeal host that contained some key components that governed the emergence of eukaryotic cellular complexity after endosymbiosis.

Other features in eukaryotic cells — for instance, the cytoskeleton — may also be of bacterial descent, but so far the molecular record has not yielded unambiguous clues as to their origin.

The genome of the archaeon known as Lokiarchaeum («Loki» for short) contains more «eukaryotic signature proteins» (ESPs) than any other prokaryote.

The EBP would focus on the natural world, providing a better understanding of biodiversity by first sequencing in great detail the DNA of a member of each eukaryotic family (about 9000 in all) and eventually generating coarser genomes for the other eukaryotes.

Martin Brasier at the University of Oxford says the stable period may also have been vital for the evolution of eukaryotic cells — cells with a nucleus of genetic material.

In previous studies, the same group along with others had demonstrated that microRNAs (miRNAs) produced by eukaryotic cells and viruses are present in human blood in highly stable, cell - free forms and these so called circulating miRNAs can serve as non-invasive biomarkers for the early diagnosis of various diseases, including viral diseases.

In last week's filing, attorneys for the Broad Institute asked patent officials to remove two of its issued patents that focus on saCas9 from the original case, as well as two other patents (and a few affiliated claims in other patents) that describe techniques for enabling the CRISPR - Cas9 construct to target the nucleus of a eukaryotic cell.

To demonstrate that the mammalian cells did not acquire bacterial genes by non-conjugational means — for example, by engulfing the bacteria, as eukaryotic cells sometimes do — Waters added an enzyme that digests DNA outside the cell membrane.

Such an autocatalytic system also provides an entirely novel mechanism for the growth of ring - shaped structures, which differs fundamentally from that used for daughter cell segregation in eukaryotic cell division: In eukaryotes, specific motor proteins which attach to the cell membrane and undergo active contraction are essential for this process, Denk points out.

Researchers from the University of Seville at the Andalusian Centre for Molecular Biology and Regenerative Medicine (Centro Andaluz de Biología Molecular y Medicina Regenerativa — Cabimer) have discovered that in eukaryotic cells the proximity of the genes to the nuclear pores, which are found in the nuclear membrane, contributes to maintaining the integrity of the genome.

A complementary DNA for the Aequorea victoria green fluorescent protein (GFP) produces a fluorescent product when expressed in prokaryotic (Escherichia coli) or eukaryotic (Caenorhabditis elegans) cells.

Until now, this initiation protein was thought to be eIF4E (eukaryotic initiation factor 4E) for all mRNAs.

The finding was a surprise because the protein is part of a larger assembly of proteins called eIF3 - eukaryotic initiation factor 3 — that has been known and studied for nearly 50 years, and no one suspected it's undercover role in the cell, Cate said.

Mitochondria are the descendants of bacteria that settled down inside primordial eukaryotic cells, eventually becoming the power plants for their new hosts.

«It's now understood to be absolutely essential for mitosis in virtually all eukaryotic cells,» Scholey said.

This and other eukaryotic mysteries may resolve more easily as geneticists refine a technique for deciphering DNA from one individual cell.

The predicted hosts for the Klosneuviruses are protists (single - celled eukaryotic (nucleus - containing) microorganisms) and while their direct impacts on protists are not yet worked out, these giant viruses are thought to have a large impact on these protists that help regulate the planet's biogeochemical cycles.

«In basic science, a lot of fundamental eukaryotic biology is studied in yeast,» said Tong Si, a Carl R. Woese Institute for Genomic Biology Research Fellow.

Our findings show that sex can generate phenotypic and genotypic diversity de novo in the pathogenic yeast C. neoformans with implications for other eukaryotic microbes and pathogens, including other fungi and parasites that are common pathogens of humans.

Legionella pneumophila (green), the bacterium responsible for severe acute lung disease inside eukaryotic cells.

Innate immune system discriminates between RNA containing bacterial versus eukaryotic structural features that prime for high - level IL - 12 secretion by dendritic cells.

The Fraunhofer IME leads the Transnational Access 1 (TNA1) «Cross platform screening and optimization service «and the corresponding Joint Research Activity (JRA1) «Improved optimization and harmonization of cross-vector screening «both aiming at the provision of comprehensive range of different well established pro- and eukaryotic expression / production systems to identify the optimal manufacturing platform for any given vaccine candidate.

Although atmospheric oxygen soon recovered again as photosynthesis and weathering reached a new balance, at about 10 per cent of present - day levels, the oxidative weathering of sulphides on land filled the oceans with sulphate which created abundant food for a group of bacteria that filled the oceans with sewer gas (hydrogen sulphide) toxic to oxygen - loving lifeforms (delaying the development of eukaryotic plants and animals) and turned them «into stinking, stagnant waters almost entirely devoid of oxygen.»

The European patent, EP 2 800 811, includes claims covering the widely adopted CRISPR - Cas9 single - guide RNA compositions for use in any non-cellular and cellular setting, including eukaryotic cells, such as mammalian, human and plant cells.

Claims cover CRISPR - Cas9 compositions for use in any non-cellular and cellular setting, including eukaryotic cells

You are what you eat: a gene transfer ratchet could account for bacterial genes in eukaryotic nuclear genomes.

«This is the highest - resolution structure of a eukaryotic Argonaute to date, which allows for more in - depth analysis of important features like its active site,» says Joshua - Tor.

Principles for RNA metabolism and alternative transcription initiation within Read more about Principes of eukaryotic RNA metabolism -LSB-...]

The Ser / Thr kinase activity of the Yersinia protein kinase A (YpkA) is necessary for full virulence in the mouse, mollifying phagocytes, and disrupting the eukaryotic cytoskeleton.

This eukaryotic cell arose when an anaerobic prokaryote (unable to use oxygen for energy) lost its cell wall.

As is often the case for yeast, the ability to sequence and analyze whole genomes at very deep coverage has yielded broad insights on eukaryotic genome evolution.

This permits fluent engineering of BACs in E.coli, and may offer new routes for directly engineering eukaryotic cells.

For example, previous studies have shown that eukaryotic translation initiation factor (eIF4E) and cyclic AMP responsive element B (CREB) are known to be activated by radiation [37 - 40].

The team's work highlights this by presenting a comprehensive view of genome evolution on many different levels (e.g., differences in ploidy, aneuploidy, genetic variants, hybridization, and introgressions) that is difficult to obtain at the same scale and accuracy for other eukaryotic organisms.

Costantini, Lindsey M., et al. «Cysteineless non-glycosylated monomeric blue fluorescent protein, secBFP2, for studies in the eukaryotic secretory pathway.

«This is the only system I know about that is amenable for structural work on how the cellular signal comes down to the chromatin and DNA and that can provide an answer about how a signal activates a eukaryotic gene,» Panne says.

The random BAC fingerprinting technique has rapidly become the method of choice for mapping and sequencing the comparatively large genomes of other eukaryotic organisms, including humans.

Recognition and utilization of clear and, for the most part mechanistically well understood, criteria will allow the delineation of bona fide miRNAs from the myriad small RNAs generated in eukaryotic cells, allowing for deeper and robust insights into their function, possible mis - regulation, and evolution.

Stephen J. Elledge, Gregor Mendel Professor of Genetics and Medicine in the Department of Genetics at Harvard Medical School and in the Division of Genetics at the Brigham and Women's Hospital and Investigator with the Howard Hughes Medical Institute, for elucidating how eukaryotic cells sense and respond to damage in their DNA and providing insights into the development and treatment of cancer.

The ability to quickly obtain accurate genome sequences of eukaryotic pathogens at low costs provides a tremendous opportunity to identify novel targets for therapeutics, develop pesticides with increased target specificity and breed for resistance in food crops.