Keiichiro Suzuki, a CRISPR expert from Salk Institute researcher, also not involved in the study, said by email: «Due to the high stability, specificity and ease for biosynthesis, the synthetic CRISPR RNA approach developed in this study will facilitate targeted genetic modification in a variety of human cells
for fundamental studies as well as therapeutic applications»
This iPS cell technology represents an entirely new platform
for fundamental studies of developmental biology.
Here we report the use of a liposomal vaccine for the generation of a monoclonal antibody with particular characteristics that makes it a valuable tool
for fundamental studies as well as a candidate antibody for diagnostic and therapeutic applications.
These capabilities were established
for fundamental studies on hydride formation and reorientation under stress with specific regard to zirconium - based nuclear fuel cladding.
Here, we show that the aforementioned 2D - zeolite models can trap individual Ar atoms in the nano - cages that make the surface, providing a new playground
for the fundamental study of isolated noble gas atoms in confinement with surface science methods.
Not exact matches
If you lack curiosity or ambition, no amount of case
studies or coaching will make up
for this
fundamental defeciency.
Indeed, the
fundamental object of
study is not the music on the page or the teacher's prowess but our imperfect fingers trying to play that music and to own it
for ourselves.
Every
study, theoretical and applied, elementary and advanced, formal and informal, is an appropriate vehicle
for teaching the
fundamental lesson of loyalty to what is true, excellent, and just.
As being can never be
studied as an independent object, the history of metaphysical thought can not be without implications
for the history of being:» [E] very science goes through a process of historical development in which, although the
fundamental or general problem remains unaltered, the particular form in which this problem presents itself changes from time to time; and the general problem never arises in its pure or abstract form, but always in the particular or concrete form, determined by the present state of knowledge or, in other words, by the development of thought hitherto.
«General education» here means
studies that are carried out with primary concern
for their universal human relevance and with due attention to those ideas of
fundamental importance which span the gulfs between the specialized disciplines.
Actually the two have been brought together in the history of Christian thought which Professor Nygren traces so superbly in his
study, but all attempts at synthesis, including that of St. Augustine with his doctrine of love as caritas, and that of the medieval theologians and mystics who saw the problem and tried to make a place
for unselfish love within the Christian doctrine, really obscured and corrupted the
fundamental Christian truth which was recovered by Luther in the Protestant Reformation.
They were inspired by what they learned and brought back many books which served as the basis
for careful
studies of the
fundamentals and consequences of Islam.
Even if the interpreter can not himself accept it as
fundamental, he has no right to conclude that it was not
fundamental for the authors whom he
studies.
The methods of pastoral theology demonstrate the value of a «thick description» as a
fundamental beginning point
for all the fields of theological
study.
This oscillatory character may be necessary, but it is of course not a sufficient condition
for living organisms, as distinct from the
fundamental particles
studied in physics.
A UN Commission on Transnational Corporations devoted about 15 years of
study and negotiation on a draft Code of Conduct
for Transnational Corporations that included a general provision requiring transnational corporations to respect human rights and
fundamental freedoms in the countries where they operate and more detailed provisions on observance of laws on labor relations and involvement of trade unions.
In Obergefell, Kennedy's claim was that although historically the interpretation of a
fundamental right to marry has not included same - sex couples, the «referenda, legislative debates, and grassroots campaigns;
studies and other writings; and extensive litigation in state and federal courts» has led to an «enhanced understanding» of how the Due Process and Equal Protection clauses of the 14th amendment contain a right
for same - sex couples to marry that was really there all along, though until now unseen.
Beyond the NICU, not accounting
for the
fundamental differences between a mother's own and donated milk also ignores broader and longer term
studies connecting mother's own milk and improved overall development and lower lifetime health and educational costs.
«These findings shed new light on
fundamental aspects of our online communication ecosystem,» says Deb Roy, an associate professor of media arts and sciences at the MIT Media Lab and director of the Media Lab's Laboratory
for Social Machines (LSM), who is also a co-author of the
study.
For my dissertation, I
studied the
fundamental mechanisms that control gene activity in plants.
In Ireland my work followed a strictly theoretical line, using
fundamental studies as the platforms
for my research.
They
studied KAP1, a gene that codes
for an essential protein associated with several
fundamental processes in neurodevelopment.
«These data are a
fundamental reference
for the radiation hazards in near Earth «geospace» out to Mars and other regions of our sun's vast heliosphere,» says CRaTER principal investigator Nathan Schwadron of the UNH Institute
for the
Study of Earth, Oceans, and Space (EOS).
«Ultimately... the consumer pays» Clark Gellings, an EPRI senior fellow and lead author of the new
study, said that the division of investments among the distribution, transmission and costumer segments should not obscure the
fundamental reality: «Ultimately, at some point, the consumer pays
for everything.»
Furthermore, bottle microresonators turn out to be ideal tools
for studying the
fundamental properties of light - matter interactions.
The proteins we identified seem to be involved in
fundamental developmental processes and we hope that functional
studies will show that some of them are ideal candidate targets
for the design of new and selective inhibitors.»
«The uncanny consistency of this stellar remnant offers intriguing evidence that the
fundamental force of gravity — the big «G» of physics — remains rock - solid throughout space,» said Weiwei Zhu, an astronomer formerly with the University of British Columbia in Canada and lead author on a
study accepted
for publication in the Astrophysical Journal.
Fundamental discoveries in biology have yielded powerful tools
for the
study of human biological systems.
«A phylogeny and taxonomy is
fundamental for all fields of biology that use lizards and snakes, to understand how to classify the species being
studied, to interpret biological patterns in terms of relatedness, and even at a more basic level, to count how many species are in an area,
for example,
for conservation management purposes.»
So the proposed regime can be groundbreaking
for a number of applications and also
for fundamental science
studies.»
The physician - scientist may
study the same properties of the same molecule but
for a different reason: because he or she believes that those
studies will provide information on the
fundamental pathology of a disease or insight into human biology that will provide a better understanding of healthy versus diseased states.
«He's been a proponent
for a long time of using humans to
study these
fundamental questions about the sense of smell,» Porter explains.
The
fundamental question
for this dementia
study was, is information available somewhere in there that people just can't get to?
The
study contributes to our
fundamental understanding of how bacteria adapt and survive under adverse conditions and provides clues about key processes that could be targeted in the search
for new antibiotics.
One common application
for quantum dots is to use them as cell markers in biomedical research, says Todd Krauss, an associate professor of chemistry and optics at the University of Rochester's Institute of Optics who
studies the
fundamental properties of quantum dots as well as their optical properties.
They're calling
for more
fundamental studies to understand how an exoskeleton and human leg interact.
In a new
study published in EPJ Plus, LARES proves its efficiency
for high - precision probing of General Relativity and
fundamental physics.
For many decades chemists and physicists have sought to understand these processes on a
fundamental atomic level and
study them in laboratory experiments.
Cahill's research group at Illinois
studies the physical mechanisms governing the interplay of spin and heat at the nanoscale, addressing the
fundamental limits of ultrafast spintronic devices
for data storage and information processing.
«This has been a very
fundamental question
for 40 years,» says
study author Christina Dwyer, a graduate student at the University of California, Santa Cruz.
► Also on Thursday, Martin Enserink provided an update on virologist Ron Fouchier, who
for the past 3 years «has battled the Dutch government over a
fundamental question in the balance between academic freedom and biosecurity: Did he need a government license to publish his hotly debated gain - of - function (GOF)
studies on the H5N1 influenza strain?»
Studying and understanding geomagnetic storms are hence
fundamental for global public and financial safety.
The
fundamental trade - off between speed and accuracy in decision making has been
studied for more than a century, with a number of
studies suggesting that the subthalamic nucleus region of the brain plays a key role.
So that scientists around the world may continue to look
for fundamental structural insights, the full, interactive imaging dataset is viewable at Mouse Connectome Project, providing a resource
for researchers interested in
studying the anatomy and function of cortical networks throughout the brain.
By adding
fundamentals of biology to their computer science training, more than a few native computer scientists are contributing — and preparing themselves to contribute — to the advancement of the life sciences (among other fields), laying foundations
for new branches of
study.
«This year's Nobel Laureates have been
studying this
fundamental problem and solved the mystery of how an inner clock in most of our cells in our bodies can anticipate daily fluctuations between night and day to optimize our behavior and physiology... since the paradigm shifting discoveries by Hall, Rosbash and Young, circadian biology has developed into a highly dynamic research field with vast implications
for our health and well - being.»
AMSTERDAM —
For more than 3 years, virologist Ron Fouchier has battled the Dutch government over a
fundamental question in the balance between academic freedom and biosecurity: Did he need a government license to publish his hotly debated gain - of - function (GOF)
studies on the H5N1 influenza strain?
The understandability of the natural world is all the more impressive when one considers the fact that
fundamental human assumptions about time and space — the idea that there are 60 minutes in an hour, and that a circle can be broken down into 360 degrees — come from a time with «no articulated sense of nature... no reference or word
for it,» according to Francesca Rochberg, professor of Near Eastern
studies at the University of California, Berkeley.
The budding yeast, Saccharomyces cerevisiae, is a prime organism
for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.
For his
study of cancer and epigenetics, «ENCODE data were
fundamental,» says Mathieu Lupien, a molecular biologist from the University of Toronto in Canada who was not associated with ENCODE.