Sentences with phrase «for gene sequencing»

«They're doing 50 genes rather than a whole exome» for a gene sequencing study.

Bray speculates that in the future, patients might submit saliva samples for gene sequencing, along with using automated sensors to collect information about factors such as their environment, diet, activity and stress.

Rudenko and Oliver send DNA from the cultured spirochetes for gene sequencing at a lab at the University of Washington in Seattle.

To this purpose, GenProfile utilizes a powerful technology platform, which involves proprietary high - throughput technologies for gene sequence comparison (e.g., multiplex sequence comparison), genotyping (MALDI - TOF minisequencing), unique approaches to data analysis and interpretation, as well as a large network of clinical collaborators.

I question why they chose to look for a gene sequence that is so common in the environment when a much more specific method could easily have been used.

Not exact matches

Given the similarities between the Canadian Patent Act and its U.S. counterpart for the definition of «invention», the Canadian Patent Office has for many years granted claims like Myriad's to isolated gene sequences and continues to do so.

The ability to locate the individual gene or gene sequence responsible for each disease could revolutionize biomedicine in the 21st century.

Speaking about the film recently in Los Angeles, Cera — who in this film, takes some refreshingly bold steps away from his usual one - note nerd persona — and co - writer / director Edgar Wright (who also did the zany cult classics Shaun of the Dead and Hot Fuzz) discussed the meaning of the film, the stretching Cera had to go through for the role, and the way in which the film's hyperkinetic action sequences are really just the same as the dance scenes in Grease or a Gene Kelly movie.

For their experiments, the researchers created hybrids of two genetically distinct mouse strains with a fully sequenced genome, allowing gene variants to be clearly assigned to the maternal or paternal allele.

Using Atlantic killifish (Fundulus heteroclitus), the researchers examined whether mitochondrial - nuclear interactions alter the frequency of alternative forms of a gene that arise by mutation, called alleles, for over 11,000 nuclear DNA sequence variations within a population of the fish with mixed ancestry.

The scientists compared the genetic sequence of five related strains of the species, looking for orphan genes and examining the life cycles of the various genes in the fly genome.

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

In 1980 Fiers first sequenced the gene for hemagglutinin derived from the human influenza strain H3N2 that circulated in 1965.

In the new study, the researchers sequenced the entire genome of mice that had undergone CRISPR gene editing in the team's previous study and looked for all mutations, including those that only altered a single nucleotide.

The even greater surprise is the recent discovery that epigenetic signals from the environment can be passed on from one generation to the next, sometimes for several generations, without changing a single gene sequence.

These are sequences made in the lab from RNA — the template used to produce the proteins that genes code for.

Which genes are activated and which are turned off is in part determined by a second tier of information which is superimposed on the nucleotide sequences that provide the blueprints for protein synthesis.

And a dog genome sequence has made the animals an even more useful model by quickening the search for disease - causing genes.

Almost immediately such familial genome sequencing proved its value, uncovering mutations responsible for diseases caused by defects in a single gene.

«Gene sequencing study reveals unusual mutations in endometriosis: Findings advance search for new ways to classify aggressive forms of the disease.»

He and his colleagues have been trawling the world's oceans for microbes and sequencing their genes.

The Tetrahymena intervening sequence (IVS) has been inserted into the gene for the alpha - donor fragment of beta - galactosidase in a recombinant plasmid.

On the other hand, by deciding that an EST sequence does not provide an adequate written description of a claim directed to «a gene,» the PTO has preserved the possibility for a gene itself to be patented once its full - length sequence is determined.

«For example, among individuals carrying the SNP sequence «TGT» at all three locations on both copies of the gene, 62 percent were blue - eyed,» says Sturm's colleague David Duffy.

The policy — in the form of first Office Actions on a series of applications for patents on expressed sequence tags, ESTs — could greatly complicate basic gene therapy research by substantially allowing patents for small sequences of a gene that may later be used by the patent holder to corner ownership and uses of entire genes.

As for the identities of Mendel's other four genes, Weeden says he expects them to be revealed in the next few years as more plant genomes give up their sequences.

The team sequenced the gene that codes for the NaV1.7 channel in mole rats, and compared it with SCN9A — a key gene in the human version of the channel.

But the predictability they did hope for could be threatened by an evolving policy on the patentability of gene sequences, which is emerging from the U.S. Patent and Trademark Office in Washington.

To build a family tree for the orchids, the scientists sequenced genes in the green structures, called chloroplasts, in which plants transform solar energy into sugar.

Using RNA sequencing, the researchers found multiple genes whose abnormal expression could lead to the high rate of death for cloned embryos, including failure to implant in the uterus and failure to develop a normal placenta.

Sequencing the genome of one such organism, King and her colleagues found genes that code for pieces of the same proteins used for the binding of cells and communication between cells in animals — functions that would be unexpected in such an organism.

Using a technique known as single - cell RNA sequencing, the team explored more than 65,000 individual cells that exist under normal or inflammatory conditions, looking for genes that were more active in one state or subpopulation versus another.

The samples were analyzed by liquid chromatography - mass spectrometry (LC - MS) to characterize the metabolite composition («metabolomics»), and biocrust DNA was extracted for shotgun sequencing to measure single copy gene markers for the dominant microbe species («metagenomics»).

But researchers had never managed to sequence Mendel's gene for seed color, and the pea genome is too huge to go fishing for it, says co-author Norman Weeden, a pea researcher at Montana State University.

The two proteins have different biochemical properties and recognize different DNA sequences, so these properties create more options for gene - editing,» said Dr. Olson, who holds the Pogue Distinguished Chair in Research on Cardiac Birth Defects, the Robert A. Welch Distinguished Chair in Science, and the Annie and Willie Nelson Professorship in Stem Cell Research.

With epigenetics we mean such changes in genes that are not determined by changes in the actual DNA sequence, but effects that are superimposed on this, caused for example by environmental effects.

«I think it's important [for journals] to be discussing this, but I think it's unrealistic to think that journals can and should play the role of the sole enforcer,» says Claire Fraser, director of The Institute for Genomic Research in Rockville, Maryland, which posts a range of microbial gene sequences online.

So, you know, the gene sequences for hemoglobin fossilize because there was no selection pressure to keep them around and, you know, like your freezing penguins they could be victimized by the warm up.

The growth of publicly accessible data troves on genome sequences, gene activity, and protein structures and interactions has opened new territory for biologists.

«We've sequenced everything on this planet, and we still don't know 149 genes that are most essential for life!»

They argue that anyone whose genome is sequenced for any medical reason should automatically learn whether 57 of their genes put them at risk of certain cancers, potentially fatal heart conditions, and other serious health problems.

They sequenced the gene coding for the receptor in patients with either severe skin allergies or hyper - IgE syndrome, a rare condition in which the body produces too much IgE.

By comparing the genetic sequences of the mutant and normal flies, the researchers found that the forgetful flies had an inactive copy of a gene that he and his Chilean collaborators dubbed Volado (Vol)-- South American slang for absentminded.

As the cost of gene sequencing drops, DNA being sequenced for one purpose may yield many other secrets, such as the risk of certain cancers and Alzheimer's disease.

Near each Crispr sequence are genes for a variety of Cas (Crispr - associated) enzymes, including Cas9.

In March three separate teams announced that they had zeroed in on a DNA sequence on chromosome 1 that carries the gene for complement factor H, a protein involved in regulating inflammation.

The trust now plans to increase its spending from $ 160 million to $ 325 million over 7 years at the Sanger Centre near Cambridge — Britain's main gene sequencing laboratory — for more painstaking efforts to sequence a third of the human genome by 2005.

But the benefits of this technology for discerning the circuits of the mind go much deeper, because the virus that carries the photoreceptor genes can also carry promoter sequences that express their payload only in neurons with the appropriate molecular address.

Before the consortium came together, he had participated in sequencing the genomes of two vocal learners, a songbird and a parrot, but he knew he couldn't do all of the additional sequencing and analysis work that would be required to identify genes related to vocal learning — not by himself, at least — so he teamed up with Genome 10K, a project aiming to collect genomes for 10,000 vertebrate species.

In tomorrow's issue of Nature, a team of scientists from The Institute for Genomic Research (TIGR) in Rockville, Maryland, will publish the complete genetic sequence of the bacterium Helicobacter pylori, spelling out the precise molecular composition of the organism's genes.