Sentences with phrase «for gene variations»

Pulling up a grid with my results, Mattingly says that in this case, I came out normal in my genetic profile for gene variations associated with mercury sensitivity.

Not exact matches

The OAR proposal uses a variation of therapeutic cloning called altered nuclear transfer (ANT) in which the nucleus of a donor cell (a skin cell, for example), containing the 30,000 genes of the genetic code, is altered in such a way that it produces an epigenetic factor, a protein called nanog.

This massive dataset is a powerful resource for understanding natural genetic variation in rice as well as for large - scale discovery of new genes associated with economically important traits.

«Some people are protected from the effects of sleep deprivation by this particular gene variation but, for most of us, sleep loss does something to the brain that simply prevents us from switching gears when circumstances change.»

Using Atlantic killifish (Fundulus heteroclitus), the researchers examined whether mitochondrial - nuclear interactions alter the frequency of alternative forms of a gene that arise by mutation, called alleles, for over 11,000 nuclear DNA sequence variations within a population of the fish with mixed ancestry.

For example, some variations of a gene are better suited for a dry climate, while other variations of that same gene are better suited for wetter environmenFor example, some variations of a gene are better suited for a dry climate, while other variations of that same gene are better suited for wetter environmenfor a dry climate, while other variations of that same gene are better suited for wetter environmenfor wetter environments.

The scientists looked for mutations, or abnormal changes in the DNA, and filtered out normal variations in genes that commonly occur among humans.

To find other genes associated with these traits, researchers will need to scan the genomes of even more women and look for less common genetic variations, says Kári Stefánsson, CEO of deCODE Genetics in Reykjavik, Iceland.

«Within the context of our emerging appreciation of polygenic risk, where gene variations are implicated in several disorders, the new findings point to only partial overlap in the risk mechanisms for these two forms of bipolar disorder,» said Dr. Krystal.

This gene, which controls the amount of melanin pigment produced, accounts for about 74 percent of the total variation in people's eye color.

In a new study published in The Quarterly Review of Biology, Dr. Karen Hardy and her team bring together archaeological, anthropological, genetic, physiological and anatomical data to argue that carbohydrate consumption, particularly in the form of starch, was critical for the accelerated expansion of the human brain over the last million years, and coevolved both with copy number variation of the salivary amylase genes and controlled fire use for cooking.

What turns out [is] that scientists are having [a] really, really hard time finding them, and what that tell [s] us is that there are these genes that influence intelligence but each particular gene is responsible for a tiny, tiny amount of variation — like a fraction of 1 percent.

Brin writes on his blog that the genome scan of his saliva from 23andMe told him he has a mutation on the LRRK2 gene, a variation called G2019S, which ups the risk for Parkinson's in some families.

For example, individuals with variations in a gene called FTO tend to desire high - calorie foods more often and have more fat as a result.

The number of copies of the resistance gene varies among cultivars; a new method, developed by University of Illinois researchers, is able to efficiently quantify this variation for the first time.

The researchers measured heritability — the amount of variation in a characteristic that can be attributed to genes — for a wide variety of human traits including blood pressure, the structure of the eyeball and mental or behavioral disorders.

Not long after the HD gene was isolated, studies led by MacDonald, also a co-author of the current investigation, found that a variation in the number of CAG trinucleotide repeats within the HD gene, which codes for a protein called huntingtin, is the primary determinant of the age at which HD symptoms appear, with a greater number of CAG repeats associated with an earlier symptom onset.

Genetic tools still under construction, such as a haplotype map that will be used to discern genetic variation behind common diseases, could further accelerate the search for disease genes.

A third of white people have gene variations that make it harder for them to quit cigarettes, and may predispose them to other addictive behaviours

Dart - biopsy samples from 195 free - ranging African elephants in 21 populations were examined for DNA sequence variation in four nuclear genes (1732 base pairs).

Researchers have known for decades that the glycophorin cluster of genes is highly variable, but it was not possible to show that this genetic variation was responsible for protecting people against severe malaria.

The team integrated three, complementary gene sequencing approaches to look for mutations in tumor cells from SS patients: whole - genome sequencing in six subjects, sequencing of all protein - coding regions (exomes) in 66 subjects, and comparing variation in the number of copies of all genes across the genome in 80 subjects.

Evolutionary biologists have long wondered why genetic variation is maintained, when there should be a «best» variant for each gene.

They discovered that genetic variation influencing a person's risk for multiple sclerosis, rheumatoid arthritis, and type 1diabetes is more likely to control gene activity in T cells than in monocytes.

The study, conducted using fruit fly populations bred to model natural variations in human sleep patterns, provides new clues to how genes for sleep duration are linked to a wide variety of biological processes.

Then, they examined the bacterial DNA, looking for patterns or variations in the microbes» genes that would help them identify specific strains of bacteria.

This research shows how global studies of our genes can give insight into how our taste for different foods may have been influenced by variation in our ability to smell, and, excitingly, show that it is possible to see back into deep evolutionary time and reconstruct the sensory world of our distant ancestors.

For one such project, the team developed a new software tool called GppFst that allows researchers to differentiate genetic drift — a neutral process whereby genes and gene sequences naturally change due to random mating within a population — from genetic variations that are indicative of evolutionary changes caused by natural selection.

There is little dispute that genetics accounts for a large amount of the variation in people's intelligence, but studies have consistently failed to find any single genes that have a substantial impact.

Researchers looked for regions of each plant's genome that showed unusual patterns of variation consistent with past selective breeding acting on the VRN - D4 gene.

Francesco Cipollone of the «G. d'Annunzio» University of Chieti, Italy, and colleagues wondered whether genetic variations in the gene for COX - 2, an enzyme that stimulates prostaglandin production, might influence heart attack and stroke risk.

«When you go back and see how much of the variation in this gene accounts for the variation in body size in the general population, it's really small,» says Bray.

Focusing on specific genes or regions is an especially good strategy for taxonomy projects, where variation in a few genes is often sufficient to place an organism on a phylogenetic tree.

«Thyroid gene variation may increase risk for Alzheimer's disease in African Americans.»

A single variation in the gene for brain - derived neurotropic factor (BDNF) may influence obesity in children and adults, according to a new study funded by the National Institutes of Health.

With the completion of the first phase of the Human Genome Project in 2000, and the advent of sequencing technologies that can detect gene variations such as single nucleotide polymorphisms (SNPs), for the first time scientists have the tools in hand to find the key immune genes and genetic networks that play roles in vaccine response.

By looking at variations in genes for hair and skin color and in the «speech» gene, we have also gained a better sense of how we are similar to and different from Neandertals.

Still, he cautions that variation in the MAO - A gene is only one of many possible risk factors for aggressive behavior.

Together, they looked at two well - known genetic risk factors for CKD in black people, the mutated G1 or G2 variations in the gene known as apolipoprotein L1 (APOL1).

Genes with mammoth - specific changes were most strongly linked to fat metabolism (including brown fat regulation), insulin signaling, skin and hair development (including genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal variations in day length in the ArGenes with mammoth - specific changes were most strongly linked to fat metabolism (including brown fat regulation), insulin signaling, skin and hair development (including genes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal variations in day length in the Argenes associated with lighter hair color), temperature sensation and circadian clock biology — all of which would have been important for adapting to the extreme cold and dramatic seasonal variations in day length in the Arctic.

They have made possible wholesale scans that turn up new gene modifications and variations, and the same should prove true for the new human gene arrays, says Joseph Ecker, a plant scientist at the Salk Institute for Biological Studies in La Jolla, California, who has helped pioneer whole - genome chips for Arabidopsis.

As it is well known that hypertension is a complex, multifactorial, quantitative trait under a polygenic control, 30 % to 50 % of the variation in blood pressure between individuals is attributed to genetic factors, and the genes responsible for susceptibility and blood pressure variation are mostly unknown.

Although bacteria have a seemingly limitless capacity to alter their genes by swapping bits of DNA between strains, this mechanism doesn't seem enough to account for the swift pace of change and the high variability of E. coli and other strains.Thomas Cebula of the U.S. Food and Drug Administration (FDA) wondered if this rapid evolution is being driven by microbes capable of much faster - than - normal variation.

A small number of known genes, it is thought, account for nearly 50 percent of pigment variation.

Indeed, the team identified high variation in adjacent «normal» tissue samples, which are typically used as control samples for comparison in analyses based on mean gene expression.

Spark Therapeutics hopes to win U.S. approval in January 2018 for a gene therapy to cure a rare inherited form of blindness, while Novartis could get a U.S. go - ahead as early as next month for its gene - modified cell therapy against leukaemia - a variation on standard gene therapy.

Additionally, researchers found that nearly 300 genes showed variation in their expression in heart tissue over the course of a day — a possible basis for the tissue's change in behavior.

Further analysis revealed that a single - letter change in the gene accounted for 46 per cent of the population's hair colour variation, with the blonde allele being recessive to the dark hair allele.

There are several variations of the gene that codes for the receptor for the hormone oxytocin.

DNA was isolated from each patient's blood and analyzed for the presence of any of six candidate genetic variations in a panel of scar formation and wound - healing genes.