Sentences with phrase «for genes controlling»

These screens were strongly enriched for genes controlling nucleocytoplasmic transport.

Andersson's group narrowed the search for the gene controlling beak size to a stretch of DNA that contains HMGA2 and three other genes.

Not exact matches

I'm not gay, nor lesbian, so I can only imagine what it would be like for those who are born with wrong genes, body, etc., to have to live in a world so full of hatred for something they have no control over.

The method identifies gene sets that show evidence for positive selection in comparison with matched controls, and thus highlights genes for further functional studies.

The worry is that «the technical ability to disaggregate and recombine genetic, gestational and rearing connections and to control the genes of offspring may... undermine essential protections for offspring, couples, family and society.»

We've been hearing about better male birth control for years now, but in recent weeks two new promising options have come to light: RISUG (reversible inhibition of sperm under guidance), being developed by an Indian scientist, Sujoy Guh, and the discovery of a gene, Katnal1, critical for sperm production; if scientists can tweak the gene with a pill, sperm production will be stalled.

Isolation is distressful for rat and mouse babies and has all sorts of ill effects like disorganizing stress response systems and undermining the expression of genes that control anxiety (McEwen, 2003; Meaney, 2001).

A total of 150 women with a history of two or more recurrent miscarriages and 20 fertile control women with no history of pregnancy losses had buccal swabs taken for DNA analyses of 10 gene mutations [factor V G1691A, factor V H1299R (R2), factor V Y1702C, factor II prothrombin G20210A, factor XIII V34L, beta - fibrinogen -455 G > A, PAI - 1 4G / 5G, HPA1 a / b (L33P), MTHFR C677T, MTHFR A1298C].

UT Southwestern biochemists studying mouse models found that the two proteins − steroid receptor coactivators 1 and 2 (SRC - 1 and SRC - 2)-- control genes for pulmonary surfactant components that promote the initiation of labor.

Chemical modifications such as DNA methylation control mammalian genes, serving as bookmarks for when a gene should be used — a phenomenon known as epigenetics.

Cells have more than one trick up their sleeve for controlling certain genes that regulate fetal growth and development.

For my dissertation, I studied the fundamental mechanisms that control gene activity in plants.

A second area challenges teams who receive funding from Safe Genes to design systems for controlling and reversing gene editing tools like CRISPR — Cas9.

The mice, which move backwards when they try to walk forwards on a smooth surface, have a gene for a mutated protein that prompts neurons in the cerebellum, a brain area that controls movement and balance, to die off.

In addition to DARPA environmentalists, biosafety experts and leading gene drive researchers say a new approach to mitigation and control is needed for the technology to advance safely.

The approach was simple but the scale was enormous, as there were multiple wells for quality control and the process was repeated for each of the approximately 20,000 human genes.

Kevin Esvelt, head of the Sculpting Evolution lab at MIT Media Lab, which is applying for Safe Genes funding in collaboration with eight other research groups, predicts that eventually, perhaps around 15 years from now, an accident will allow a drive with potential to spread globally to escape laboratory controls.

Unravelling the epigenetic control of the lactase gene involved a collaborative effort of CAMH, University of Toronto, the Hospital for Sick Children, Vilnius University and the Lithuanian University of Health Sciences.

Next, Anderson and his colleagues used a set of genetic tools to identify exactly which neurons were responsible for the effect on aggression and to see if the gene that encodes for Tk also controls aggressive behavior by acting in that cell.

The researchers identified for the first time master genes that they believe control hundreds of other genes which are linked to Alzheimer's disease, Parkinson's disease, post-traumatic stress disorder, stroke, attention deficit hyperactivity disorder, autism, depression, schizophrenia and other disorders.

The most common mutations, occurring in five of the women, occurred in genes including ARID1A, PIK3CA, KRAS and PPP2R1A, all known for controlling cell growth, cell invasion and DNA damage repair.

After demonstrating the existence of several genes that control indefinite cell division, she, a grad student named Yi Ning, and their colleagues found a candidate for one of those genes on chromosome 4.

She also sought out genes that controlled the switch for maturation of T helper cells, maintaining just the right balance of T helpers — between Th1 cells that suppress allergic responses and Th2 cells that trigger them.

The new method may make some types of gene therapy easier and could be a boon for researchers hoping to control gene activity in animals, scientists say.

This gene, which controls the amount of melanin pigment produced, accounts for about 74 percent of the total variation in people's eye color.

In a new study published in The Quarterly Review of Biology, Dr. Karen Hardy and her team bring together archaeological, anthropological, genetic, physiological and anatomical data to argue that carbohydrate consumption, particularly in the form of starch, was critical for the accelerated expansion of the human brain over the last million years, and coevolved both with copy number variation of the salivary amylase genes and controlled fire use for cooking.

Hypoxia - inducible factor 1α (HIF - 1α), an oxygen sensor that controls the expression of various genes for glucose metabolism under conditions of low oxygen levels, is the most well documented substrate of the von Hippel - Lindau (VHL) enzyme.

With genes that helped them produce higher - quality eggs for a longer period of time, the TGF - β mutants had double the reproductive span as control worms.

In light of this shortcoming, some investigators see room for an increased focus on an alternative explanation for heritable traits: epigenetics, the molecular processes that control a gene's potential to act.

By using pairs of sisters who spent differing amounts of time living with their fathers, the study was able to control for inherited genes and environmental conditions, such as socioeconomic status or religious background, to isolate the effects of fathering quality on daughters.

Hence the term gene drive for this prospective new weapon in pest control.

Surprisingly, the cancer - promoting program that RB - loss unleashed was distinct from the cell - cycle control genes that RB is best known for controlling.

Using previous data, Orkin and his team identified the BCL11A gene as a candidate for controlling the molecular switch.

Directly or indirectly, Holick points out, «the active form of vitamin D controls up to 200 different genes,» including ones responsible for cell proliferation, differentiation, and death.

This bundling of DNA acts as a switchboard for controlling genes» activity and directs a cell's complex molecular machinery.

Even after the cells were taken out of microgravity for up to 30 generations before being combined with the control strain, they maintained 72 per cent of their adaptive advantage, pointing to permanent mutations in the genes rather than merely a temporary adjustment.

Other techniques exist for remotely controlling the activity of cells or the expression of genes in living animals.

Purdue University researchers have pinpointed the gene that controls whether soybean seed coats are hard or permeable, a finding that could be used to develop better varieties for southern and tropical regions, enrich the crop's genetic diversity and boost the nutritional value of soybeans.

Many of the additional 38 missing genes looked like they coded for proteins involved in controlling the activity of other genes.

Molecular geneticists dream of having a similarly comprehensive view of networks that control genes: For example, they would like to identify rules explaining how a single DNA sequence can express different proteins, or varying amounts of protein, in different circumstances (see p. 80).

That's why sequencing the genome was important, he said, because it will help identify all the genes and enzymes in the genome needed for hydrocarbon production and control of this production.

Chao and colleagues found CTL1 while screening for genes that control ion homeostasis in the model plant, Arabidopsis thaliana.

«As a result of the previous study, we reported that SUMO is probably important for controlling expression of active genes because we found it on every gene we looked at, but only when they were turned on,» notes Rosonina.

They discovered that genetic variation influencing a person's risk for multiple sclerosis, rheumatoid arthritis, and type 1diabetes is more likely to control gene activity in T cells than in monocytes.

Using an innovative crystallization technique for studying three - dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the «magic spot» — a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

New research has found that the pharmaceuticals, which are frequently showing up in U.S. streams, can alter genes responsible for building fish brains and controlling their behavior

Making up 98 percent of the genome, these regions do not code for proteins, but they contain «switches» that like a conductor control when and where genes are expressed.

Aedes has already been shown to possess extra genes for receptors that detect odors, for proteins that help it purge pesticides from its system, and for controlling the makeup of its outer shell.

Within the duplicate regions, Carmona - Mora and her colleagues discovered many switches, known as enhancers, important for controlling activity of genes.

Though this is true for some traits, we now know that many traits are controlled by tens or even hundreds of genes spread throughout our genomes.