Sentences with phrase «for genomic studies»

As a recognized cornerstone for the genomics research community, AGBT provides an outstanding forum for exchanging information about the latest advances in DNA sequencing technologies, experimental and analytical approaches for genomic studies, and their myriad applications.

AGBT provides a forum for exchanging information about the latest advances in DNA sequencing technologies, experimental and analytical approaches for genomic studies, and their myriad applications.

$ 25M was committed by NHGRI to its Large - Scale Sequencing and Analysis Centers (LSACs) for genomic studies.

Wolf's team measures the young birds» wing length and color and collects blood samples for genomic studies before returning them to the nest.

Not exact matches

But it has been disappointing in that the kind of genetic variation it detects has turned out to explain surprisingly little of the genetic links to most diseases... One issue of debate among researchers is whether, despite the prospect of diminishing returns, to continue with the genomewide studies, which cost many millions of dollars apiece, or switch to a new approach like decoding the entire genomes of individual patients.The unexpected impasse also affects companies that offer personal genomic information and that had assumed they could inform customers of their genetic risk for common diseases, based on researchers» discoveries...

One such example is a paper called «Of woods and webs: possible alternatives to the tree of life for studying genomic fluidity in E. coli».

The work helps explain a biological mystery and could open scientific doors to studies of novel treatments for neurological disease, said lead researcher Jason Slot, an assistant professor of fungal evolutionary genomics at The Ohio State University.

«Discovery of this mutation adds to the growing list of insights gained from genomic studies that can be used to develop new treatments and customize existing treatments for type 2 diabetes and related metabolic disorders,» Dr. Damcott says.

EPFL scientists have carried out a genomic and evolutionary study of a large and enigmatic family of human proteins, to demonstrate that it is responsible for harnessing the millions of transposable elements in the human genome.

Among those are grants for very high - throughput genomics and proteomics studies.

«We found that Amish people with this mutation have defects in fat storage, increased fat in the liver, high triglycerides, low «good» (HDL) cholesterol, insulin resistance and increased risk of developing type 2 diabetes,» says the study's senior author, Coleen M. Damcott, Ph.D., an assistant professor of medicine in the Division of Endocrinology, Diabetes and Nutrition and member of the Program for Personalized and Genomic Medicine at the University of Maryland School of Medicine.

«We now hope to design larger clinical studies to treat patients» tumors harboring these novel genomic aberrations to further explore the precise extent of clinical benefit for patients with primary or advanced cholangiocarcinoma.»

«The study results elucidate the molecular mechanisms underlying disease progression in multiple sclerosis models, providing a basis for future clinical trials to determine safety and efficacy of these chemical agents in humans with demyelinating disorders,» says Patrizia Casaccia, MD, PhD, Professor of Neuroscience, Genetics and Genomic Sciences at Mount Sinai and senior author of the study.

I was studying a handful of families in which people had inherited a recessive disease affecting platelet aggregation, looking for mutations in their genomic DNA.

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (TGen).

As costs come down and methods become more standardized, experts in the field expect single - cell sequencing to become the new model for both transcriptomic and genomic studies.

The study has involved the participation of groups from the «Centro Nacional de Investigaciones Oncológicas,» the «Hospital Clínico de Barcelona - IDIBAPS - UB,» and the Centre for Genomic Regulation.

The study's principal investigator, Dr Riccardo Marioni, from The University of Edinburgh's Centre for Genomic and Experimental Medicine, said: «We are still a long way from making an accurate prediction for an individual's hair loss pattern.

Google Genomics, for instance, is studying the application of cloud computing to genomics, and Calico has signed a slew of collaborations with companies and academic institutes.

Ehrhardt says he believes that the decline in NIH - funded studies can be traced to two things: Flat NIH funding (the 2014 budget was 14 percent less than in 2006, after adjusting for inflation) and greater competition for these limited dollars from other, relatively new research areas such as genomic research or personalized medicine studies.

In a study that included children and young adults with relapsed or refractory cancer, incorporation of integrative clinical genomic sequencing data into clinical management was feasible, revealed potentially actionable findings in nearly half of the patients, and was associated with change in treatment and family genetics counseling for a small proportion of patients, according to a study in the September 1 issue of JAMA.

A genome - wide association study (GWAS) of 1570 Africans identified variants significantly associated with skin pigmentation, which clustered in four genomic regions that together account for almost 30 % of the phenotypic variation.

In the current study, for example, they utilized genomic information from hundreds of microbial species commonly found in humans to create computer models of nutrient and energy metabolism.

A chromosome - specific BAC library was used to assemble 82 % of the chromosome into 1036 contigs that were anchored with 1443 molecular markers, providing a major resource for genetic and genomic studies.

He stayed on for a Ph.D., specialising in bioinformatics and the design of computer tools for the study of evolutionary genomics.

The study also indicated that genomic diversity may also have useful clinical applications for predicting tumor invasion, metastasis and poor survival in patients.

Xin Liu, Project Manager from BGI, said «This study not only generates valuable genomic resource including additional wild reference genome, genome - wide variations for further studies and breeding applications on cucumber, but also gave us a better picture about how the cucumber genome evolved during domestication.

I was riding high on a series of recent academic honors for my work studying toxigenic molds and was looking forward to spending a sabbatical leave at The Institute for Genomic Research, now the J. Craig Venter Institute, in Maryland.

Dr Sid Banka from the Manchester Centre for Genomic Medicine at The University of Manchester, led a team of researchers on the study which is published in Annals of Rheumatic Diseases journal.

Aime said that the study also highlighted the importance of fungaria as scientific resources for the genomic age.

«This study demonstrates the value of testing lung cancer tissue for an ALK rearrangement, and it underscores the potential of cancer genomics to target cancer treatments to each patient,» says the study's senior author, Pasi A. Jänne, MD, PhD, who is the director of the Lowe Center for Thoracic Oncology of Dana - Farber.

«First, there is no single road map to eusociality — the complex, cooperative social system in which animals behave more like superorganisms than individuals fending for themselves,» said Gene Robinson, a lead on the study who is a professor of entomology and director of the Carl R. Woese Institute for Genomic Biology at the University of Illinois.

«Our study provides an example of the utility of comparative genomics and evolutionary models for medicine,» Sunyaev said.

In 2010 the Deciphering Developmental Disorders (DDD) study was established to find diagnoses for children with unknown developmental diseases using genomics.

Dr. Jones obtained his Ph.D. in 2003 from the University of Birmingham Institute of Cancer and Genomic Sciences (United Kingdom) under Professor Lawrence Young, studying the use of gene therapy for targeting Epstein - Barr Virus (EBV) proteins with replication - competent adenoviruses to treat EBV - driven malignancies.

«There was a major gap for researchers using genomic DNA sequences to understand the evolution of species complexes,» says Ryan Folk, lead author of a study in a recent issue Applications in Plant Sciences.

If the findings of the study are replicated in other animal models, such as pigs, they could have considerable implications for public health, says Oluf Pedersen, professor of genomic medicine at the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen.

For example, some human genomic studies involving different ethnicities from different countries need scientific collaboration.

Although «genomic rearrangements have been associated with autism for awhile,» finding more of the novel changes is «quite exciting for the field,» says Simon Gregory, an associate professor of medical genetics at Duke University's Center for Human Genetics, who was not involved in the study.

The Deciphering Developmental Disorders (DDD) study aims to find diagnoses for children with as yet unknown developmental diseases, and demonstrate that new genomic technologies can provide improved diagnostic tests.

For the study, which was published in Nature Communications, the group performed whole genomic sequencing on 30 individual tumors classified as liver cancer displaying a biliary phenotype.

Results for different genomic partitions, methods, and data types are consistent with or contradict clades in our TENT ExaML, TENT MP - EST *, and exon - only trees and previous studies of morphology (15), DNA - DNA hybridization (24), mitochondrial genes (14), and nuclear genes (17).

«Even when the genes driving cancer are known, clinicians don't have an efficient way to choose among the hundreds of possible drug therapies,» said study leader Kai Wang, PhD, associate professor of biomedical informatics and director of clinical informatics at the Institute for Genomic Medicine at CUMC.

The new study describes a method for targeting introns by utilizing publicly available genomic data to find these rapidly evolving regions.

«The world of genomics is beginning to open up for people like me who don't study model organisms,» Egan said.

Lead authors of the study, Ivan P. Gorlov, Ph.D., Associate Professor of Community and Family Medicine and Christopher Amos, Ph.D., Professor of Community and Family Medicine and Director of the Center for Genomic Medicine described a new method to analyze microarray data.

Many of the genomic projects will eventually lead to interesting targets for structural biological studies.

Dr Siddharth Banka, Clinical Senior Lecturer at the Manchester Centre for Genomic Medicine, who led the study, explained: «Our team has identified that this new syndrome is caused by a small deletion on chromosome 6 that affects the function of hypothalamus, a region of the brain that plays a number of important roles in the body.»

«For anorexia nervosa, researchers implicate genetic locus on chromosome 12: Powerful genomic study of anorexia nervosa conducted to date to identify the common roots anorexia shares with psychiatric, metabolic traits.»

Professor Qian said, «The study has provided genomic resources for understanding how the deep - sea mussel has adapted to the abiotic stresses and lack of photosynthesis - derived food in the deep - sea chemosynthetic environment.