Now, scientists have shown that supplementing healthy mice with NMN — found in foods such as broccoli, avocado, cabbage, and cucumber — can compensate
for this loss of energy production, reducing typical signs of aging such as
gradual weight gain, loss of insulin sensitivity and declines in physical activity.
Average long - term
weight gain in nonobese populations is
gradual — in the cohorts we studied, about 0.8 lb per year — but accumulated over time, even modest increases in
weight have implications
for long - term adiposity - related metabolic dysfunction, diabetes, cardiovascular disease, and cancer.21 - 24 Whereas
weight changes associated with any single lifestyle factor were relatively modest in our three cohorts, in the aggregate, changes in diet and physical activity accounted
for large differences in
weight gain.