Sentences with phrase «for high disease»

Not exact matches

Novartis, Amgen, and BAI are trying to figure out whether or not an experimental treatment called CNP520 can delay Alzheimer's in the people at high risk for the disease — or prevent it altogether.

Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the effect of global economic conditions on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns on pension plan assets and the impact of future discount rate changes on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the effect of changes in tax law, such as the effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the effect of such changes; 21) any reduction in our credit ratings; 22) our dependence on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.

«If we determine that our [treatment] can prevent or delay the onset of symptoms in healthy yet high - risk populations, this would represent a tremendous breakthrough for those that may face this debilitating disease.»

Spending on new drugs for those diseases is expected to rise 7 % in 2018, and it's less due to price hikes as it is for the high prices associated with these specialty therapies.

Increasingly, that growth will be driven by millennials, the oldest of whom have lifted the annual birthrate for women 30 to 34 to the highest level since 1964, according to the U.S. Centers for Disease Control and Prevention.

But for most households, high debt is the disease, not the cure, and adding more debt to «stimulate spending» is like trying to put out a fire with gasoline.

For one thing, margarine is high in Omega 6 fatty acids, which has been linked «to an increased risk for heart disease and may contribute to cancer, asthma, osteoporosis, inflammation, depression and other ailments.&raqFor one thing, margarine is high in Omega 6 fatty acids, which has been linked «to an increased risk for heart disease and may contribute to cancer, asthma, osteoporosis, inflammation, depression and other ailments.&raqfor heart disease and may contribute to cancer, asthma, osteoporosis, inflammation, depression and other ailments.»

So your cholesterol test is going to tell you if you have high cholesterol, which is a risk factor for heart disease.

It also helps select for survival the strains of the fungus with higher levels of resistance to these chemicals: As the resistant strains become more prevalent, the disease gets harder to control over time.

Because those who fly on jet airplanes frequently face higher exposure to cosmic radiation, the Centers for Disease Control and Prevention (CDC) classifies airline crew members as radiation workers.

«Bringing new biosimilars to patients, especially for diseases where the cost of existing treatments can be high, is an important way to help spur competition that can lower healthcare costs and increase access to important therapies,» said FDA Commissioner Scott Gottlieb in a statement.

LONDON / ABIDJAN, May 1 (Reuters)- Ivory Coast's move to halt the distribution of high - yielding seeds and other advanced tools to cocoa farmers could pave the way for problems regarding quality, more erratic production and the spread of diseases, industry sources warn.

The Centers for Disease Control is reportedly aiming its latest series of anti-smoking ads in areas where smoking rates are the highest.

* Ivory Coast's move to halt the distribution of high - yielding seeds and other advanced tools to cocoa farmers could pave the way for lower quality, more erratic output and the spread of diseases, industry sources warn.

The numbers in Europe are substantially higher than those in the United States, where the Centers for Disease Control and Prevention reported just 118 cases throughout 2017.

One of the most high - profile cases involved Oprah Winfrey, who was sued in 1998 by a group of Texas ranchers for a show in which she swore off eating hamburgers because of mad cow disease.

Data from a number of other studies, including the Nurses» Health Study and the Health Professionals Follow - up Study also report greater risk of type 2 diabetes, high blood pressure, heart disease and metabolic syndrome, which is related to diabetes and cardiovascular problems, for consumers of artificially sweetened beverages.

Americans overall have high risks for diabetes and heart disease.

According to the Center for Disease Control and Prevention (CDC), nearly 12 % of high school females had experienced physical violence and nearly 16 % had experienced sexual violence from a partner in the year before they were surveyed.

Mannkind, which focuses on the development and commercialization of inhaled therapeutic products for patients with diseases such as diabetes and pulmonary arterial hypertension, entered a shallow but persistent downtrend in 2004, posting a series of lower highs into 2015.

Minoryx is a clinical stage biotech company leading the development of new therapies for X-linked Adrenoleukodystrophy (X-ALD) and other inborn errors of metabolism, a group of rare diseases of genetic origin with a high unmet medical need.

While high price tags are common for rare disease drugs, Emflaza is part of a class of drugs called corticosteroids that are used for DMD in other parts of the world.

While most of the attention on pharmaceutical prices has been on new drugs for diseases like cancer, hepatitis C and high cholesterol, there is also growing concern about huge price increases on older drugs, some of them generic, that have long been mainstays of treatment.

But you know, at least we've some political diseases like our friendly dictator, daily racism, changing law backward, incredibly high establishment costs and very high taxes for nothing... I said nothing?!

Contamination from upstream tar sands / oil sands development is causing higher levels of cancer and other serious disease for members of the Athabasca Chipewyan and...

Katherine High, Spark's president and chief scientific officer, expressed her enthusiasm for the early clinical data related to SPK - 8011: «The encouraging start of our SPK - 8011 clinical trial reinforces the strength of our gene therapy platform, delivers human proof - of - concept in a second liver - mediated disease — a significant achievement in the gene therapy field — and positions us well to potentially transform the current treatment approach for this life - altering disease with a one - time intervention.»

In general, companies that are «diseased» but «curable» offer better prospects for high returns than those that are held in favor by everyone with a few dollars to invest.

According to an analysis of fatal and nonfatal childhood firearm injuries compiled by the Centers for Disease Control and Prevention, black children face the highest rates of firearm mortality, a difference largely driven by black youth being more likely to face a firearm homicide.

According to a 2017 analysis of fatal and nonfatal childhood firearm injuries compiled by researchers from the Centers for Disease Control and Prevention, black children face the highest rates of firearm mortality — a difference largely driven by black youth being more likely to be shooting victims than children from other racial groups.

Maastricht, The Netherlands, 1 November 2017 — Cristal Therapeutics, a clinical stage biopharmaceutical company developing targeted nanomedicines for the treatment of cancer and other diseases with high unmet patient need, announced today that it has begun a Phase 1b...

When women routinely win Nobel Prizes in physics, chemistry or medicine, when a woman becomes a world chess champion, when a woman conceives and develops a brand new computer chip that represents a significant advancement over quad cores, when a woman invents warp drive or phasers, when a woman solves an «insolvable» math problem, when a woman, while working with the Large Hadron Collider, discovers the now - hypothetical Higgs Boson to be an actual scalar subatomic particle, when a woman figures out how to pinpoint the exact location of an electron at any point in time, when a woman working for Merck or Pfizer develops a remedy for Alzheimer's disease, when a woman's baseball team can defeat the New York Yankees, when a woman can bench press six hundred pounds, run the 100 meter dash in under nine seconds or set a world record in the high jump, then the fairer sex will have made an advance or contribution unlike any it has made before.

(I'm guessing if I met her she might well be the kind of person who volunteers at a food pantry, runs a business with high ethical standards, sends money each month to an orphanage in Guatemala, and prays regularly for a neighbor stricken with a terminal disease.)

(I say this in spite of the monistic utterances of many mind - cure writers; for these utterances are really inconsistent with their attitude towards disease, and can easily be shown not to be logically involved in the experiences of union with a higher Presence with which they connect themselves.

I myself will never adopt an understanding that the power to overcome «disease» or sin or «sickness» or whatever alcoholism is, can be received from, or operated with, «something» or «somebody» or a «power greater than myself» or a «higher power» or a «group» or a light bulb, chair, bulldozer, goddess, doorknob, radiator or any of the other «absurd names for God» (as Rev. Sam Shoemaker, our «cofounder» described them).

Now, maybe it isn't God's will for Christians to have lower disease rates, lower death rates, lower accident rates, lower food poisoning rates, lower child injury rates, and higher job promotion rates.

For those with chronic aches and pains, insomnia, nausea, appetite issues, crohn's disease, and migraines, look for Purple Kush a pure indica strain with a very heavy hiFor those with chronic aches and pains, insomnia, nausea, appetite issues, crohn's disease, and migraines, look for Purple Kush a pure indica strain with a very heavy hifor Purple Kush a pure indica strain with a very heavy high.

When looking at incest, for instance, it is quite clear that permitting consanguineous relationships will lead to power imbalances, psychological damage, sexual abuse, and a high rate of genetic diseases.

With all due respect to In»N Out, Chick - Fil - A and Tyson, I don't need you to state your «morals» to know what you stand for — poisoning our country through your disgusting fat foods which makes our citizens obese and leads to a significantly higher risk to many deadly diseases.

This means you can rest assured that out standards are the highest and our Gluten Free Bread crumbs are safe for a person with Celiac disease, anyone who has chosen to eat gluten free and tastes great so is enjoyed by the entire family.

I like spicy things, but I also don't have a high tolerance for spicy things (nor does my reflux disease).

Pulses, also known as legumes, lentils, and beans are a nutritious way to add high protein, high fiber, and low carbohydrates to a gluten - free diet for people with celiac disease, gluten - intolerence, or wheat allergies.

Packed with high protein, low in fat, and full of fiber, this soup is a complete meal perfect for people with celiac disease, or who have wheat, gluten, and milk allergies.

[1] While oats are a cereal grain with a very high risk of contamination from gluten - containing grains (GCGs), it is now generally accepted that pure oats uncontaminated with GCGs can be safe for persons who have celiac disease.

People at high risk for heart disease should strive for 500 mg or less.

Triglycerides are a form in which fats are carried in the blood, and high triglyceride levels are associated with an increased risk for heart disease, so ensuring you have some monounsaturated fats in your diet by enjoying cashews is a good idea, especially for persons with diabetes.

It turns out that traditional fats are good for you, and that saturated fats in particular do not cause heart disease and high cholesterol.

Insulin promotes the storage of fat, so that when you eat foods with a high GI, you're making way for rapid weight gain and elevated triglyceride levels, both of which have been linked to cardiovascular disease.

Psyllium use may also help you properly regulate your blood glucose levels, and a diet high in soluble fiber can potentially help you reduce your risks for developing heart disease.

According to the Centers for Disease Control, about 75 million American adults have high blood pressure (that's 1 in 3 adults).

Even though almonds are high in fat, they are a way for you to reduce the risk of getting heart disease.