Sentences with phrase «for human breast cancer»

Tamoxifen, a product commonly used for human breast cancer, is ineffective and has the potential for serious side effects in dogs.

Researchers have now identified a gene mutation in canine lung cancer that they believe can be targeted with a drug currently FDA approved for human breast cancer.

Unlike previous MRI studies of tumors in mice, the researchers were able to detect very small naturally occurring cancers, which were excellent models for human breast cancer; the tumors the mice developed were «realistic models of the most frequently detected human cancers,» the authors wrote.

Using these multidimensional datasets for human breast cancer, PLK4 was identified as a candidate target among 10,000 other targets for the development of anticancer therapeutics.

Not exact matches

As a human being you can't help but cheer for someone whose beaten breast cancer.

Additionally, the U.S. Department of Health and Human Services finds that women who breastfeed their babies probably lower their risk for developing breast cancer, type 2 diabetes, ovarian cancer, postpartum depression, and rheumatoid arthritis.

A number of witnesses were to testify in favor of a marriage equality plank in the platform: Marc Solomon, national campaign director for Freedom to Marry; Allison Herwitt, legislative director for the Human Rights Campaign; Army Chief Warrant Officer Charlie Morgan, a lesbian New Hampshire guardsman with stage - four incurable breast cancer and a plaintiff in Servicemembers Legal Defense Network's lawsuit against the Defense of Marriage Act; Michael Macleod - Ball, the American Civil Liberties Union's chief of staff for the Washington Legislative Office; and Aaron Zellhoefer, a gay delegate to the Democratic National Convention representing the National Stonewall Democrats.

To cover the cost of medication for managing cervical and breast cancers under the health insurance but ignoring children cancers isunjust and abuse of fundamental human rights of Ghanaian children — right to access to healthcare.

The researchers «deserve a lot of credit» for testing the approach in the mice that spontaneously develop breast tumors, he says, which more closely mimic how cancer arises in humans.

Then the researchers turned to the lab, where they exposed human liver, breast, colon, ovarian, and other cancer cells to the drugs, which appeared to make it easier for the cells to migrate.

She expects she will find laminum - 8 uniquely overexpressed in other invasive cancers, like lung and colon cancer, but to date she has tested for it in only human brain and metastatic breast cancer.

«There are still many questions left to answer but we now know that oxygen poor environments, like those often found in advanced human breast cancers serve as nurseries for the birth of cancer stem cells,» says Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine and a member of the Johns Hopkins Kimmel Cancer Ccancer stem cells,» says Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine and a member of the Johns Hopkins Kimmel Cancer CCancer Center.

«These results confirm that TMEM sites and MenaINV are essential for the spread of breast cancer in humans,» said Dr. Oktay.

Exploiting the same pre-clinical model used for their studies, the researchers are testing the efficacy of this kind of drug candidates against cancer stem cells, and the possibility of identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the treatment of human breast cancer.

In many human breast cancers, Numb concentration is low and this is associated with a poor prognosis for the patients.

«If further studies validate that these processes are critical in human breast cancers,» Koshy notes, «the possibility exists that agents that favorably modify the biophysical properties of the extracellular matrix, or that target the receptors and signaling molecules associated with how cells sense this matrix, could be used as a new avenue for the prevention or treatment of breast cancers.»

Previous evidence for a breast cancer link has been mixed — one study found increased risk in women exposed before age 14, whereas others found no association — but in a lab dish, DDT has been shown to activate the HER2 gene in human breast cells, which is expressed in some breast cancers.

The ability of the ITAM sequence to make cells cancerous represents a potential new trigger for breast cancer in humans, say the researchers, and gives further credence to the idea that viruses can cause human breast cancer.

The idea that a virus can cause human breast cancer has been around for nearly fifty years.

This study provides one of the first animal models to demonstrate the long - term cognitive deficits resulting from a chemotherapeutic treatment used in treating humans for breast cancer.

For years researchers have been developing molecular imaging techniques that visualize hormonally active breast cancer cells — specifically those testing positive for human epidermal growth factor receptor 2 (HERFor years researchers have been developing molecular imaging techniques that visualize hormonally active breast cancer cells — specifically those testing positive for human epidermal growth factor receptor 2 (HERfor human epidermal growth factor receptor 2 (HER2).

Regulation of the inflammatory profile of stromal cells in human breast cancer: prominent roles for TNF - a and the NF -?

PALLAS: Palbociclib Collaborative Adjuvant Study: A Randomized Phase III Trial of Palbociclib with Standard Adjuvant Endocrine Therapy versus Standard Adjuvant Endocrine Therapy Alone for Hormone Receptor Positive (HR +) / Human Epidermal Growth Factor Receptor 2 (HER2)- Negative Early Breast Cancer

Dr. Jos Jonkers» research group studies the genetic basis of human breast cancer, using advanced mouse models for p53 - induced breast cancer, BRCA1 - and BRCA2 - associated hereditary breast cancer, and E-cadherin mutated invasive lobular carcinoma.

«In particular, his approach can be thought of as a very advanced biological therapy for the treatment of breast cancer; one that uses viruses, which are better recognized to cause disease, to treat human breast cancers.»

To uncover how groups of cancer cells achieve functional diversity (through RNA) to survive chemotherapy, Lopez - Diaz dosed dishes of human pre-cancer and metastatic breast cancer cells with the cancer drug paclitaxel for a week and then removed the drug for a few weeks, mimicking the treatment cycle for a cancer patient.

Elected by his peers, Liu was recognized for his distinguished contributions to cancer biology, particularly the molecular analysis of breast cancer, and to the global advancement of human genomics.

Aug 8, 2008 Two New Predisposition Genes For Breast, Thyroid And Kidney Cancers Could Lead to More Accurate Diagnosis and Earlier Detection of These Cancers Charis Eng, MD, PhD, Sondra J and Stephen R Hardis Endowed Chair of Cancer Genomic Medicine and Chair, GMI, and her team published in the Aug 8, 2008 issue of the American Journal of Human Genetics that germline mutations in SDHB and SDHD, which play key roles in the mitochondria (the cell's power houses), predispose to Cowden and Cowden - like syndromes.

Conditions for hypoxia / reoxygenation cycles were optimized using two human metastatic breast cancer cell lines (MDA - MB 231 and BCM2).

Should collaborations like these prove to be important also in human breast cancer, disrupting key interactions may be a novel treatment strategy for the disease.

Chemotherapy is a key part of the standard treatment regimen for triple - negative breast cancer patients whose cancer lacks expression of estrogen and progesterone receptors and the human epidermal growth factor receptor 2...

«We have found that the same genes responsible for tamoxifen resistance in our animals are also turned off in human breast cancer cells that do not respond to the drug,» she says «Because these genes were epigenetically silenced — meaning they were not irreversibly altered, just switched off — it was possible to turn them back on.

Triple negative breast cancer is a type of breast cancer that does not express receptors for the hormones estrogen and progesterone, or for human epidermal growth factor.

Low levels of a tiny RNA fragment in cells are associated with metastatic breast cancer in humans and increases the aggressive spread of breast cancer in mice, according to researchers at Whitehead Institute for Biomedical Research.

Robert D. Schreiber, Ph.D., an associate director of CRI's Scientific Advisory Council based at Washington University School of Medicine in Saint Louis, Missouri, developed a new model of breast cancer that more closely resembles the progression of hormone receptor - positive disease in humans, overcoming a major obstacle in the study of breast cancer and the development of new immune - based therapies for the disease.

These kind of mice are an extraordinary resource for modeling human disease; for instance, research has found that mice that are genetically mutated to carry the BRCA1 gene (a human breast cancer gene) behave more similarly to human cancer patients than those mice who have had a tumor physically transplanted in.

«It is believed that environmental and lifestyle factors, such as diet, play a critical role in increasing human breast cancer risk, and so we use animal models to reveal the biological mechanisms responsible for the increase in risk in women and their female progeny,» says Hilakivi - Clarke.

Mitochondrial folate transport by SLC25A32 is yet unstudied for its contribution to oncogenesis, despite knowledge that the slc25a32 gene is amplified in human cancers (including > 40 % of breast cancers) and this amplification is associated with accelerated disease progression and death.

Many women are «triple negative» No one yet knows precisely why, but African - American women are roughly twice as likely as white women to have triple - negative breast cancer — so called because tumor cells in this particularly aggressive form of the disease test negative for estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER - 2).

Although no specific dosage for humans has been determined yet, it seems that maintaining a minimal amount of apigenin in the bloodstream is beneficial for delaying the onset of breast cancer which progresses as a result of progestins like MPA.

Epidemiologic data has shown that chronic depression, stress, and lack of social support are all risk factors for cancer.14 A study in humans even showed chronic depression and even the death of a mother during childhood to be associated with increased breast cancer in women.15 While we do not have concrete evidence in humans, animal studies more definitively point to stress as a cause of cancer.

(5, 6) In fact, the importance of sleep is only now becoming more widely recognized for its many impacts on human health, with links being established between sleep deprivation and blood sugar problems, high blood pressure, obesity, even breast cancer.

Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention.

Genistein Inhibits Both Estrogen and Growth Factor — stimulated Proliferation of Human Breast Cancer Cells Cell Growth & Differentiation 1996 (Oct); 7 (10): 1345 — 1351 Genistein is a naturally occurring dietary protein tyrosine kinase (PTK) inhibitor that is hypothesized to be responsible for the lower rate of breast cancer observed in Asian women consuminBreast Cancer Cells Cell Growth & Differentiation 1996 (Oct); 7 (10): 1345 — 1351 Genistein is a naturally occurring dietary protein tyrosine kinase (PTK) inhibitor that is hypothesized to be responsible for the lower rate of breast cancer observed in Asian women consuminCancer Cells Cell Growth & Differentiation 1996 (Oct); 7 (10): 1345 — 1351 Genistein is a naturally occurring dietary protein tyrosine kinase (PTK) inhibitor that is hypothesized to be responsible for the lower rate of breast cancer observed in Asian women consuminbreast cancer observed in Asian women consumincancer observed in Asian women consuming soy.

Beet extract is studied for its anticancer properties in human breast, pancreatic, colon, and prostate cancer.

Guidelines for the appropriate use of herbs in human preliminary research see promise in the use of dandelion as an anti-cancer agent for both breast and prostate cancer.

Its red color comes from the anthocyanins which at the same time provide anti-cancer properties.Beet extract is studied for its anticancer properties in human breast, pancreatic, colon, and prostate cancer.

Enhanced fat burning through green and white tea - brown fat cells play key role 13.07.2017 Two cups of green tea daily results in more brown fat 25.04.2017 Animal study: half cup of green tea daily is life extending 15.04.2017 Speed up interval - training fat loss with supplement containing caffeine and green tea 19.01.2016 Green tea boosts fat burning after interval training 30.10.2015 Chin - Shin Oolong Tea contains growth hormone booster 02.10.2015 Green tea healthier and more effective on empty stomach 01.09.2015 EGCG speeds up muscle recovery after period of inactivity 19.05.2015 Green tea inhibits breakdown of fast muscle fibres during long - term inactivity 18.05.2015 Five cups of green tea daily rejuvenates skin 10.09.2014 Quercetin boosts inhibitory effect of green tea for prostate cancer 27.01.2014 Slimming supplement containing ECGC, resveratrol and Grape Seed Extract shown to work in human study 12.01.2014 Tea protects prostate against testosterone 10.12.2013 Green tea speeds up muscle recovery after heavy training 11.11.2013 EGCG protects liver and kidneys, and extends life expectancy 04.08.2013 EGCG and caffeine supplement keeps the cold out 26.02.2013 N - oleyl - phosphatidyl - ethanolamine & EGCG combo makes weight - loss diet easier 03.02.2013 Green tea has a slightly anabolic effect on strength athletes 14.01.2013 Cup of green tea with a meal makes it easier to eat less 18.12.2012 Green tea keeps athletes fit as the years go by 24.10.2012 Mushrooms, green tea reduce chance of breast cancer by factor of 10 13.10.2012 Combination of strength training and green tea gives elderly more muscle mass 12.10.2012 One cup of green tea burns five grams of fat 02.09.2012 Tiny amount of caffeine can burn fat — when combined with tea phenols 27.08.2012 Tea for temporary T boost 24.04.2012 Grow old healthily with green tea 11.03.2012 Tea drinkers have stronger bones 25.02.2012 Lose weight with Pu - Erh tea 17.08.2011 Tea supplement boosts T levels in animal study 30.10.2010 Almost no green tea in green tea sodas 13.10.2010 Drink green tea instead of water — and live longer 24.05.2010 Green tea stackers don't work without exercise 13.05.2010 Metastudy: slimming supplements with green tea do work 27.03.2010 Black tea reduces muscle soreness after training 20.03.2010 Cold brewed white tea contains most antioxidants 04.01.2010 Cup of tea inhibits uptake of mercury from fish 04.12.2009 Polyphenols in juice and tea clear bacteria from your teeth 22.10.2009 Drink three cups of tea a day and add five years to your life 11.09.2009 Bad breath from proteins?

A review of HCAs showed that certain HCAs are distributed to the mammary gland and that humans can activate HCAs metabolically.24 As a consequence, frequent meat consumption may be a risk factor for breast cancer.22

Importantly, however, we don't view our dog patients as test subjects for cancer research, but they can help us to better understand breast carcinoma in both dogs and humans and fight it more effectively.»