Sentences with phrase «for human cancer treatment»

Inequity in how cats vs. dogs included in medical research for human cancer treatments; 5th annual Saving Pets Challenge; positive effects of fostering cats on emotional / mental state of elderly

Not exact matches

There are currently two types of cancer vaccines available: preventive, for human papillomavirus and hepatitis B; and treatment, for metastatic prostate cancer.

It will take at least a couple of years for Theralase Technologies Inc.'s cancer treatment technology to become regulated (and at least a year before we know how well it works on humans), but the healthcare tech they have under development is worth talking about.

Those who feel there is something «unnatural» about introducing human genes into animals or plants forget that we share a high proportion of our genes with these species already: it is precisely this collective heritage that allows experiments on frogs to spawn treatments for human cancer.

That's how Charles Sawyers, a 2009 Lasker Award winner and chair of human oncology and pathogenesis at Memorial Sloan - Kettering Cancer Center in New York City, made the connection with Bristol Myers Squibb (BMS) that led to second - generation treatments for chronic myeloid leukemia (CML).

«Our results suggest that engineered human intestine could provide a viable treatment to lengthen the gut for patients with gastrointestinal disorders, or patients who lose parts of their intestines due to cancer,» said Bitar.

Pseudomonas aeruginosa is usually harmless to humans, but in people with cystic fibrosis (CF) or who have weakened immune systems — such as those who have had an operation or treatment for cancer — it can cause infections that are resistant to antibiotics.

A dozen human studies of MDMA, LSD, a powerful African drug called ibogaine and psilocybin, from so - called «magic mushrooms,» are now under way, testing the once - stigmatized drugs as treatments for not only PTSD, but also cluster headaches and addiction, as well as anxiety and depression in cancer patients.

«Everything we talked about was about research directly on the embryo,» for example, to improve on infertility treatment or better understand cancer biology, says R. Alta Charo, a law professor and bioethicist at the University of Wisconsin Law School who was a member of the NIH Human Embryo Research Panel in the mid-1990s, which considered how embryos might be used in research.

The research will also enhance understanding of how cancers avoid the immune system, which could have implications for cancer treatment in humans.

Exploiting the same pre-clinical model used for their studies, the researchers are testing the efficacy of this kind of drug candidates against cancer stem cells, and the possibility of identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the treatment of human breast cancer.

Scientists at Dana - Farber Cancer Institute have identified natural human antibodies against the virus that causes Middle East Respiratory Syndrome (MERS), a step toward developing treatments for the newly emerging and often - fatal disease..

She helped lead a GSK project focused on designing a monoclonal antibody to link to the HER3 receptor on human cells as a treatment for cancer.

The use of bone marrow - derived stem cells is well established in the treatment of human cancer patients, and veterinary applications for bone marrow - and adipose - derived stem cells are being evaluated.

Her research is both translational and clinical in nature and centers on the human genetics of healthy skin aging and diseases related to aging skin, including new treatments for advanced basal cell skin cancers.

Triple - negative cancers are so called because they do not express receptors for the hormones estrogen and progesterone, nor for HER2 (human epidermal growth factor 2), and hence patients with these cancers are not candidates for treatment with modern hormonal therapies or the highly effective HER2 - targeted drug Herceptin (trastuzumab).

«If further studies validate that these processes are critical in human breast cancers,» Koshy notes, «the possibility exists that agents that favorably modify the biophysical properties of the extracellular matrix, or that target the receptors and signaling molecules associated with how cells sense this matrix, could be used as a new avenue for the prevention or treatment of breast cancers.»

It's not all just fun and games: Understanding how cells — especially white blood cells — navigate through the human body could help scientists create better treatments for cancer, infectious disease, and autoimmune disorders.

So - called cancer immunotherapy — which is the treatment of tumors by the use of antibodies — has been established and used very successfully in human medicine for about 20 years.

The first anti-EGFR antibody (cetuximab) for cancer treatment in human medicine was developed by the company Merck.

And because their signal blocker is an antibody already in phase I clinical trials for cancer treatment, they're hoping to make a quick jump into human testing for cardiovascular disease.

Richard Lindsay, a PhD student who worked on the research team, added: «Our findings are of central importance in understanding how microbial infections evolve, but also have wider significance for the treatment of cancer and the therapeutic control of disease in humans, animals and plants.»

Buoyed by these results, Dana - Farber researchers are working to create a derivative of dBET1 that can be used as a drug in human patients — and to extend the conjugate strategy for the treatment of other cancers and other genetically - caused diseases.

«First human application of novel PET tracer for prostate cancer: New tracer holds promise of monitoring targeted treatment of various cancers.»

This study provides one of the first animal models to demonstrate the long - term cognitive deficits resulting from a chemotherapeutic treatment used in treating humans for breast cancer.

In a 1988 paper summarizing his findings, Fiebig concluded that xenograft mice were wonderful models for broadly testing new drugs against human tumors, but they «can not be used as a clinical routine method» for predicting patient treatment.1 The idea of using xenograft mice as personal avatars for cancer patients was discarded.

This apparently symbiotic relationship within tumors has provocative implications for the study and treatment of human cancers.

This center fosters collaborations among researchers at MD Anderson Smithville, in Houston and with other instutions in central Texas to reach the goal of understanding how environmental exposures influence cancer outcomes in the human population by identifying new targets and strategies for cancer prevention and treatment.

«In particular, his approach can be thought of as a very advanced biological therapy for the treatment of breast cancer; one that uses viruses, which are better recognized to cause disease, to treat human breast cancers.»

Society for Natural Immunity (SNI) Symposium Towards Treatment of Human Cancer with NK Cells Saturday, May 5, 12:30 PM — 2:30 PM, Room 12AB Chairs: Hans - Gustaf Ljunggren, Karolinska Inst.

Other HDAC inhibitors are in development for cancer treatment, and these, rather than trichostatin A, are more likely candidates for human SMA trials in the future.

The dream of personalized treatment for cancer patients takes a major step forward today with the launch by Swedish researchers of the Human Pathology Atlas.

To uncover how groups of cancer cells achieve functional diversity (through RNA) to survive chemotherapy, Lopez - Diaz dosed dishes of human pre-cancer and metastatic breast cancer cells with the cancer drug paclitaxel for a week and then removed the drug for a few weeks, mimicking the treatment cycle for a cancer patient.

MD Anderson is working closely with Guardant to expand a highly specialized CLIA - accredited lab (CLIA labs comply with federal standards known as the Clinical Laboratory Improvement Amendments that regulate all clinical laboratory testing on humans), and pre-CLIA labs, where Guardant's digital sequencing technology will be used to create disease - specific assays that will be transferred for use in the CLIA - accredited lab to help detect cancers early and guide treatment.

Canine and human comparisons represent an unprecedented opportunity to complement conventional endocrine tumour research paradigms, addressing a devastating group of cancers for which innovative diagnostic and treatment strategies are clearly needed.

She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.

April 15, 2013 Cancer treatment pioneers share prestigious medical prize Janet Davison Rowley, MD, the Blum - Riese Distinguished Service Professor of Medicine, Molecular Genetics & Cell Biology and Human Genetics at the University of Chicago, is one of three physician - scientists who will receive the Albany Medical Center Prize in Medicine and Biomedical Research for 2013.

• Patients must have adequate coagulation (international normalized ratio (INR) or prothrombin time (PT), partial thromboplastin time (PTT) ≤ 1.5 times ULN) • Adequate liver function (total bilirubin ≤ 1.5 times the ULN, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ≤ 2.5 times ULN Exclusion Criteria: • Presence of active / uncontrolled central nervous system involvement • History of clinically significant cardiac disease; uncontrolled hypertension • Left ventricular ejection fraction (LVEF) < 45 % • Allogeneic stem cell transplant within 100 days before first dose of study drug • Known history of human immunodeficiency virus (HIV) infection • Chronic or active hepatitis B or C, requiring antiviral therapy • Evidence of history of bleeding disorder, dialysis, or coexisting cancer that is distinct in primary site or histology from the cancer evaluated in this study • Serious, uncontrolled infection • Unresolved chronic toxicity > grade 1 from prior therapy • Use of strong CYP3A4 inhibitors or strong inducers within 7 days prior to the start of study treatment and for the duration of the study

Clinical Trials Research and Billing First in Human / Early Phase PET in Oncology Case - Based Dose Reduction in Pediatric Nuclear Medicine: Practical and Necessary Radioiodine Therapy for Hyperthyroidism: The State of the Art Spondylodiscitis: Role of Imaging for Diagnosis and Monitoring Treatment Response Current Status and Future Prospects: PET and SPECT Instrumentation Alternative Payment Models and Value - Based Health Care: Nuts and Bolts Maximal Tolerated Activity of Radioactive Iodine for Metastatic Thyroid Cancer Teaching Old Radiopharmaceuticals New Tricks Intraoperative Detection Devices and Probes Molecular Imaging of Lung Inflammation Standardization of Advanced PET / SPECT Data Acquisition and Analysis Thyroid Cancer Management: Novel Therapeutics and Management Options Targeting Radionuclide Therapy in Various Non-Malignant Arthritic Conditions Using Radiosynoviorthesis (RSO) Are You Prepared for a Radiation Accident?

Should collaborations like these prove to be important also in human breast cancer, disrupting key interactions may be a novel treatment strategy for the disease.

mTOR is particularly tantalizing as a drug target because the FDA, which regulates which drugs can be used in humans, has already approved some mTOR inhibitors for cancer treatment and in organ transplants.

Chemotherapy is a key part of the standard treatment regimen for triple - negative breast cancer patients whose cancer lacks expression of estrogen and progesterone receptors and the human epidermal growth factor receptor 2...

By supporting Directive 2010 / 63 / EU, LERU wishes to call attention to the fundamental importance of the use of animals in research and the vital role it plays in understanding and providing treatment for a range of debilitating and life threatening human diseases such as cancer, primary immunodeficiencies, neuro - degenerative diseases and heart failure.

Farokhzad and colleagues have considerable expertise with bench - to - bedside translation of nanotechnologies for medical applications, and foundational work done in part by his team has led to the development and first in human testing of a targeted nanoparticle capable of controlling drug release for treatment of cancers, and the first in human testing of a targeted nanoparticle vaccine capable of orchestrating an immune response to facilitate smoking cessation and relapse prevention.

He was one of three co-chairs of the National Cancer Institute's Translational Research Working Group, which worked to reengineer translational cancer science across the nation, and has been a member of the scientific advisory boards of several companies focused on the development of new technologies and treatments for human cancer, a member of the American Association of Cancer Research's Board of Directors, President of the National Coalition for Cancer Research, and a member of the Scientific Advisory Board of the Prostate Cancer FoundCancer Institute's Translational Research Working Group, which worked to reengineer translational cancer science across the nation, and has been a member of the scientific advisory boards of several companies focused on the development of new technologies and treatments for human cancer, a member of the American Association of Cancer Research's Board of Directors, President of the National Coalition for Cancer Research, and a member of the Scientific Advisory Board of the Prostate Cancer Foundcancer science across the nation, and has been a member of the scientific advisory boards of several companies focused on the development of new technologies and treatments for human cancer, a member of the American Association of Cancer Research's Board of Directors, President of the National Coalition for Cancer Research, and a member of the Scientific Advisory Board of the Prostate Cancer Foundcancer, a member of the American Association of Cancer Research's Board of Directors, President of the National Coalition for Cancer Research, and a member of the Scientific Advisory Board of the Prostate Cancer FoundCancer Research's Board of Directors, President of the National Coalition for Cancer Research, and a member of the Scientific Advisory Board of the Prostate Cancer FoundCancer Research, and a member of the Scientific Advisory Board of the Prostate Cancer FoundCancer Foundation.

Population expansion may be a major driver in the evolution of cooperation, with implications for new antibiotics, cancer treatments and perhaps even human behavior.

We can envision that DAXX can serve as a precise prognostic marker in PCa and that tissue - specific shRNA delivery targeted against DAXX can be employed in the treatment of metastatic prostate cancer in patients, in particular if we discover, through additional studies, that DAXX is a marker for lethal PCa in humans.

Helicobacter pylori, a bacterium known for its ties to gastric cancer, may have health benefits for the human immune system, potentially opening doors to new treatments for gastrointestinal infections.

They are used in many areas of human health, including as nutritional supplements by athletes and as treatments for burns, neurological disorders, AIDS, cancer and late - stage kidney failure.

My interests lie in leveraging the information hidden in large - scale omics data for better understanding of the mutational processes causing human cancer, for identifying potential cancer prevention strategies, and for developing novel approaches for targeted cancer treatment.