Sentences with phrase «for human exposures at»

Not exact matches

An FDA draft report concluded that the substance was safe at typical exposure levels for humans.

In animal models, exposure to cigarette smoke or nicotine during fetal development alters the expression of the nicotinic acetylcholine receptor in areas of the brainstem important for autonomic function, 28 alters the neuronal excitability of neurons in the nucleus tractus solitarius (a brainstem region important for sensory integration), 29 and alters fetal autonomic activity and medullary neurotransmitter receptors.30 In human infants, there are strong associations between nicotinic acetylcholine receptor and serotonin receptors in the brainstem during development.31 Prenatal exposure to tobacco smoke attenuates recovery from hypoxia in preterm infants, 32 decreases heart rate variability in preterm33 and term34 infants, and abolishes the normal relationship between heart rate and gestational age at birth.33 Moreover, infants of smoking mothers exhibit impaired arousal patterns to trigeminal stimulation in proportion to urinary cotinine levels.35 It is important to note also that prenatal exposure to tobacco smoke alters the normal programming of cardiovascular reflexes such that there is a greater - than - expected increase in blood pressure and heart rate in response to breathing 4 % carbon dioxide or a 60 ° head - up tilt.36 These changes in autonomic function, arousal, and cardiovascular reflexes might all increase an infant's vulnerability to SIDS.

They also tracked Apolipoprotein E (APOE 4), a well - known genetic risk factor for Alzheimer's, as well as lifetime cumulative exposure to unhealthy levels of PM2.5 — particles which are at least 30 times smaller than the diameter of a human hair and frequently cause the haze over urban areas.

«Our research provides the first direct evidence that exposure to BPA during development, at the levels we see in our day - to - day lives, increases the risk for prostate cancer in human prostate tissue,» Prins said.

The ATS recommended standards for O3 and PM2.5 are based on scores of national and international epidemiological, animal and human exposure studies.

This year «s Young Scientist Award on human health sciences, presented at the EUROTOX annual meeting in Stockholm, Sweden, has been awarded to Camille Béchaux, Anses France for her poster presentation on: Dynamical modeling of dietary exposure to dioxins and corresponding present and future health risk: A case study in France

This center fosters collaborations among researchers at MD Anderson Smithville, in Houston and with other instutions in central Texas to reach the goal of understanding how environmental exposures influence cancer outcomes in the human population by identifying new targets and strategies for cancer prevention and treatment.

But for the majority of us who don't work with chemicals, diet is the biggest source of exposure, says Jorge Chavarro, MD, assistant professor of nutrition and epidemiology at Harvard School of Public Health and senior author of a new study published in the journal Human Reproduction.

The study has earned high marks from researchers not on the soy industry's payroll, including Dan Sheehan, PhD and Daniel Doerge, PhD at the FDA's National Laboratory for Toxicological research in Jefferson, Arkansas.who stated, «Given the great difficulty in discerning the relationship between exposures and long latency adverse effects in the human population and the potential mechanistic explanation for the epidemiological findings, this is an important study.

Among various food items, cow's milk and cheese had the highest correlation with incidence and mortality rate of these cancers» Children are at high risk «Among the exposure of humans, especially prepubertal children, to exogenous estrogens, we are particularly concerned with» These xenoestrogens from lactating preganant cattle (the majority of commercial cattle used for milk) significantly raised estrogen levels in male adults and reduced testosterone levels and did even more so in children.

Recent exhibitions include Steam Work at Southern Exposure, San Francisco; Attractions at High Desert Test Sites (HDTS), Utah; R.S.V.P. Los Angeles at the Pomona College Museum of Art; Remembering Victor Papanek at the Armory Center for the Arts, Pasadena; Shitwork with Machine Project at HDTS, California; Juicework at Human Resources, Los Angeles; and The Unfinished at the Bowtie Project, Los Angeles.

At the same time, I support Ryan O.'s concern about the need for quantitative arguments; I find personal attacks unacceptable in a scientific discussion; finally, from my experience I think that exposure of one's research to specialists in different fields can be extremely productive, to say nothing about the fact that as scientists are working for the humanity, speaking with educated human beings the scientist is speaking with the ultimate consumer of his / her work, which entails both sides to a mutual respect.

Examples of such cases are Chandler v Cape Plc [2011] EWHC 951 (QB)(liability of non-employer for exposure to asbestos), Kynixa Ltd v Hynes and others [2008] EWHC 1495 (QB)(claims arising from alleged breaches of restrictive covenants in employment contracts), Romantiek BVBA v Simms [2008] EWHC 3099 (QB) a claim alleging that a public official had committed the tort of misfeasance in public office when discharging a licensing function, OOO and others v The Commissioner of Police for the Metropolis [20011] EWHC 1246 (QB)(claims by young foreign females that they had been trafficked into the UK by foreign nationals for the purpose of slavery and that officers of the Metropolitan Police Force breached their human rights in failing to investigate their complaints adequately or at all) and Mouncher and others v The Chief Constable of South Wales Police [2016] EWHC 1367 (QB)(claims by retired and serving police officers for false imprisonment, misfeasance in public office and malicious prosecution against South Wales Police arising from an investigation by officers of that force into alleged criminal conduct on the part of the claimants during the course of an investigation into a notorious murder in South Wales.

Responsible for the assessment of potential human health effects from exposure to environmental contaminants at and around hazardous waste sites