Not exact matches
For now, Porteus and his team found that their corrected
human hematopoietic stem cells seemed to behave like normal, healthy
human hematopoietic stem cells.
Human hematopoietic stem and progenitor
cells (HSPCs), derived from bone marrow, have become a primary vehicle
for efforts to replace or regenerate
cells destroyed by a variety of diseases.
Zhao and his colleagues are also investigating whether a megakaryocyte niche can be used to help expand
human hematopoietic stem cells in vitro and
stem cell transplantation
for patients.
In Lifemap, the HaemAtlas dataset provides gene expression
for adult
human B
cells, helper T
cells, natural killer
cells, granulocytes, and monocytes while the
Hematopoietic Fingerprints dataset provides gene expression information
for postnatal
stem cells and their progeny.
While
human cord blood represents a potentially important source of
hematopoietic stem and progenitor
cells (HSPC), current two dimensional (2D) growth conditions employed to amplify
cell numbers to the level required
for many regenerative applications lead to a decline in the absolute percentage of the most primitive HSPCs [1].
Recent papers published by groups from UC Berkeley and Stanford University have described methods
for the genetic manipulation of primary
human hematopoietic stem and progenitor
cells (HSPCs) that require them to be maintained in vitro
for anywhere from 24 hours to more than a week.
Targeted Gene Addition to a Safe Harbor locus in
human CD34 +
Hematopoietic Stem Cells for Correction of X-linked Chronic Granulomatous Disease.
He is the principal investigator of an NCI - funded, multi-million-dollar Specialized Program of Research Excellence (SPORE) in ovarian cancer, and he is the principal investigator of a multi-million-dollar grant from the New York State
Stem Cell Science program (NYSTEM) to pioneer a novel strategy of reprogramming human mature T cells and hematopoietic stem cells for generating sustained attack against ovarian cancer in patie
Stem Cell Science program (NYSTEM) to pioneer a novel strategy of reprogramming
human mature T
cells and
hematopoietic stem cells for generating sustained attack against ovarian cancer in patie
stem cells for generating sustained attack against ovarian cancer in patients.
Dr. Péault is internationally recognized principally
for his work on the prospective identification and characterization of
human hematopoietic (blood)
stem cells, of which his laboratory has also deciphered the ultimate origin during embryonic life.
Human placenta and chorion: potential additional sources of
hematopoietic stem cells for transplantation.
A quantitative assessment of the content of
hematopoietic stem cells in mouse and
human endosteal - bone marrow: a simple and rapid method
for the isolation of mouse central bone marrow.
Zonari E, Desantis G, Petrillo C, Boccalatte FE, Lidonnici MR, Kajaste - Rudnitski A, Aiuti A, Ferrari G, Naldini L, Gentner B. Efficient ex vivo engineering and expansion of highly purified
human hematopoietic stem and progenitor
cell populations
for gene therapy.