Not exact matches
The document was crafted to help foodservice distributors — and other members of the foodservice supply channel — plan
for the far - reaching effects of a
human influenza pandemic.
As carriers — and fertile mixing grounds —
for influenza A strains that could cause illness or even pandemic in
humans, hogs are important subjects
for flu researchers.
Pigs can catch
human strains as well, and
influenza is one of the most costly porcine pathogens
for the $ 19 - billion, 113 - million - hog U.S. industry.
In 1980 Fiers first sequenced the gene
for hemagglutinin derived from the
human influenza strain H3N2 that circulated in 1965.
Nelson and her colleagues found that flu in pigs «follows long - distance swine movements from the southern U.S. to the Midwest,» with most of the
human - origin H1N1 arriving at Midwest hog farms coming from the Southeast, and most of the swine - origin H1N2 coming from the south - central U.S. And that means the Midwest, as the final destination
for many of these pigs, is «likely to provide a reservoir
for multiple genetically distinct variants to co-circulate and exchange segments via re-assortment because of the continual importation of swine
influenza viruses from other regions,» the researchers noted.
These animals are common hosts
for the
influenza virus, which comes in a wide range of strengths and types — some of which can infect
humans.
Weiner, Elliott and colleagues studied the DNA sequences
for two
human monoclonal antibodies — one able to broadly target
influenza A viruses and one able to broadly target
influenza B viruses — with collaborators at Inovio and MedImmune.
If further studies in
humans prove successful, this research could have broad implications
for the prevention of
influenza and, by extension, as an approach
for other infectious diseases as well.
The new flu, known as H7N9 avian
influenza, latches onto sugars that coat bird cells — and it can cling to sugars on
human cells too, Yuelong Shu of the China Center
for Disease Control and Prevention and colleagues...
«I'm not saying that everyone who has
influenza is cognitively impaired
for 10 years,» he says, noting that
human brains are much more complex than those of mice.
Unlike flu viruses that affect
humans, the eight
influenza genes in this H1N1 changed very little
for 6 decades.
It's been well researched, by studies, by world organizations, by the Centre
for Disease Control in Atlanta, other organizations that have all unanimously come to the conclusion that consumption of pork is not a risk factor
for transmission of
influenza virus from swine to
human.
It shows that a particularly troublesome strain of avian
influenza, designated H5N1, which has been worrying public health officials
for more than a decade, has the potential to become a
human pandemic.
And of particular concern is the fact that pig cells are uniquely receptive to
influenza viruses from swine,
humans, and birds, making swine a dangerous «mixing vessel»
for new variants.
The loss was bad
for the vaccine: In a series of experiments Hensley and his colleagues showed antibodies from
humans and ferrets (a good animal model
for influenza A studies) that had been exposed to the egg - grown vaccine did not effectively kill the circulating sugar - adorned viruses.
Using the RNAi and CRISPR / Cas9 screening technologies they'd developed
for dengue and
influenza, George Savidis, research associate, Paul Meraner, MD, postdoctoral fellow, and William M. McDougall, PhD, postdoctoral associate, in the Brass lab, began by knocking out or depleting each protein in the
human genome one at a time, then seeing how Zika or dengue virus grew when that
human protein was gone.
Indeed, weakening
influenza strains by passaging them in animals is an old technique
for making
human vaccines, including those
for polio and yellow fever, according to virologist Vincent Racaniello of Columbia University.
Humans are the only known hosts
for Haemophilus
influenzae bacteria, a family comprised of many different strains, the most well - known of which is type b, or Hib.
«Ferrets may be the best model
for influenza, but ferrets in cages treated with antipyretics are very different from
human populations,» he says.
Through a process called recombination, which had not previously been seen in
influenza viruses, parts of the
human and swine virus genes had joined together to create a totally new antigen, one that
human immune systems were unprepared
for (Science, 11 May, p. 1041).
Thus, avian A / H5N1
influenza viruses can acquire the capacity
for airborne transmission between mammals without recombination in an intermediate host and therefore constitute a risk
for human pandemic
influenza.
The support, announced here at the International Pledging Conference on Avian and
Human Pandemic
Influenza, far exceeds the $ 1.5 billion expected, according to a statement issued by European Commissioner
for Health and Consumer Protection Markos Kyprianou.
The new flu, known as H7N9 avian
influenza, latches onto sugars that coat bird cells — and it can cling to sugars on
human cells too, Yuelong Shu of the China Center
for Disease Control and Prevention and colleagues report July 3 in Nature.
The three labs together identified several hundred
human genes that
influenza hijacks
for its own benefit, but in most cases the groups each hit on different ones: Only about 30 genes overlap, an outcome that's «very surprising,» says Peter Palese, a virologist at Mount Sinai School of Medicine in New York City, who co-authored the paper with Chanda.
One of the more intriguing findings came out of a choice in Elledge's lab to hunt
for human proteins that interfere with
influenza virus replication, as opposed to those that assist it.
The
influenza virus makes itself at home in
human cells and hijacks our proteins
for its own ends.
Clinical samples were also sent to an outside laboratory (Focus Diagnostics, Cypress, CA)
for respiratory viral testing by centrifugation - enhanced shell vial culture followed by direct fluorescent antibody staining
for 8 viruses (respiratory syncytial virus, adenovirus,
influenza virus A and B, parainfluenza virus types 1, 2, and 3, and
human metapneumovirus).
For influenza we offer the ferret model, the «gold standard» for infections with human influenza viruses, which will be used to assess the efficacy of vaccine candidat
For influenza we offer the ferret model, the «gold standard»
for infections with human influenza viruses, which will be used to assess the efficacy of vaccine candidat
for infections with
human influenza viruses, which will be used to assess the efficacy of vaccine candidates.
Influenza A virus (IAV) and influenza B virus (IBV) are responsible for seasonal epidemics of respiratory illness amon
Influenza A virus (IAV) and
influenza B virus (IBV) are responsible for seasonal epidemics of respiratory illness amon
influenza B virus (IBV) are responsible
for seasonal epidemics of respiratory illness among
humans.
Proteins targeted
for structure determination by SSGCID are selected
for their biomedical relevance in
human pathogens such as Ebola and Zika, as well as those responsible
for tuberculosis, leprosy, malaria, and
influenza.
In April 2017, Moderna published
human data
for its mRNA vaccine technology in Molecular Therapy, which showed that its first prophylactic vaccine candidate, mRNA - 1440 — an mRNA prophylactic vaccine against avian H10N8
influenza — induced high levels of immunogenicity and was safe and well tolerated.
The study relates to a particular type of vaccine (killed) against a particular virus,
influenza, though the findings might hold true
for other killed vaccines and
for those vaccines consisting only of proteins produced by GM in bacteria, yeast or insect cells, against diseases such as hepatitis B (HBV) and
human papilloma virus (HPV, the causative agent of cervical cancer).
The idea behind a â $ œHuman Vaccine Projectâ $ is to combine efforts at developing vaccines
for major (but very different) diseases such as
influenza, dengue, HIV, hepatitis C, tuberculosis and malaria, with the rationale that what scientists working on those diseases have in common is the Ray Ban outlet challenge of working with the
human immune system.
Pigs are natural hosts
for influenza viruses that can infect
humans, in particular the 2009 and, going way back, 1918 H1N1 flu strains.
«Using an animal model that's relevant to
human disease, Fouchier and Kawaoka have shown that relatively few mutations may be required
for an
influenza virus to evolve into astrain that can pass effectively between individuals and cause serious illness.
Three Emory scientists have signed a letter published last week in Nature and Science outlining proposed research on the H7N9 avian
influenza virus. A strain of H7N9 transmitted from poultry to
humans was responsible
for 43 deaths in China earlier this year, but so far, evidence shows that the virus does not transmit easily from
human to
human.
Waisman Biomanufacturing, notes Ross, has a long history of producing experimental vaccines
for clinical trials, including
for HIV,
influenza, hepatitis, herpes and
human papillomavirus, among others.
The study, «Preferential Recognition of Avian - Like Receptors in
Human Influenza A H7N9 Viruses,» received support from the National Institutes
for Health (R56 AI099275), the Skaggs Institute
for Chemical Biology, the Scripps Microarray Core Facility, the Centers
for Disease Control and the Netherlands Organization
for Scientific Research.
From WebMD: «Lauric acid is used
for treating viral infections including
influenza (the flu); swine flu; avian flu; the common cold; fever blisters, cold sores, and genital herpes caused by herpes simplex virus (HSV); genital warts caused by
human papillomavirus (HPV); and HIV / AIDS.
However,
influenza viruses are constantly changing via random mutation and it is possible
for a virus to mutate so that it could one day cross infect and spread easily between
humans.
Canine
influenza viruses (CIV) have never been proven to be transmissible to
humans, but it's always best to err on the side of safety and take precautions to disinfect when caring
for a sick pup, especially if there are other dogs in the house.
Something like 70 percent of
human diseases generally start in animals first (avian
influenza, mad cow, chronic wasting disease) and then spread to
humans, so we're seeing more demand
for public health specialists.
For example, unlike
human flu, canine
influenza does not follow a season.
The Centers
for Disease Control (CDC) monitors the
human influenza virus and updates how vaccines are produced to provide maximum protection.
He has also generated attenuated viruses as vaccine candidates,
for the treatment of
influenza and arenavirus infections in
humans and other mammalians.
Considering that people can be infected regardless of vaccination status and that not everyone will be immunized, it's important that we recognize the potential
for humans to pass a microorganism like the
influenza virus to our pets.
While
humans can't contract canine
influenza, we can carry the virus on our hands and clothing
for up to 24 hours after handling an infected dog.
Canine
influenza spreads the same way that
human flu spreads - through direct contact (kissing, licking, nuzzling); through the air (coughing or sneezing from 20 + feet away); and via contaminated surfaces (surfaces such as concrete where the virus can live
for up to 48 hours).
«As
for other species becoming infected, there have been no reports or evidence that H3N2
influenza can infect
humans.
However,
influenza viruses are constantly changing and it is possible
for a virus to change so that it could infect
humans and spread easily between
humans.