Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control
for human mesenchymal stem cell culturing.
In an effort to improve this, we employed an alginate encapsulation strategy
for human mesenchymal stem cells (hMSCs) and attached them to the heart with a biocompatible PEG hydrogel patch in a rat MI model.
Not exact matches
It also provides novel insight into
human mesenchymal stem cell - heart
cell interactions that can guide future experimental studies to understand the mechanisms underlying
mesenchymal stem cell therapy
for the heart.
«The introduction of mitochondria into damaged
cells has beneficial effects on the health of
cells and, in the long term, we believe that
mesenchymal stem cells could even be engineered to create more effective therapies
for lung disease in
humans.»
[2] S. Zeitouni et al., «
Human mesenchymal stem cell - derived matrices
for enhanced osteoregeneration,» Sci Transl Med, 4:132 ra55, 2012.
Human mesenchymal stem cells (hMSCs) are currently the most common adult
stem cell type used
for cell therapy applications due to their regenerative properties and ability to differentiate into multiple
cell lineages (adipocyte, chondro ¬ cyte, and osteocyte).
Human mesenchymal stem cells (hMSCs) have become a popular potential therapy
for numerous autoimmune and neurological disorders.
Researchers from the laboratories of Hiroshi Y. Yoshikawa and Hideki Taniguchi had previously demonstrated the in vitro formation of a 3D transplantable liver «organ bud» from
human induced pluripotent
stem cells (iPSCs) co-cultured with
mesenchymal and endothelial progenitors, and allows
for the growth of a small vascularized and functional organ [1 - 3].
Allogeneic
Mesenchymal Stem Cells Stimulate Cartilage Regeneration and Are Safe
for Single - Stage Cartilage Repair in
Humans upon Mixture with Recycled Autologous Chondrons.
The self - renewable capacity of these
cells, their ability to differentiate into several tissue progenitors (neural,
mesenchymal stem cells...), and the possibility to work with mutated
cell lines define
human stem cells as a good basis
for screening compounds libraries in order to discover new potential drugs
for monogenic diseases.
Here, authors from Corning Life Sciences describe dissolvable microcarriers as a scalable solution
for large - scale expansion and harvest of functional
human mesenchymal stem cells by enabling simplified downstream processing and high - yield
cell recovery.