Centocor Johnson & Johnson, Radnor • PA 2007 — Present Associate Scientist Accountable for performing manual and automated operations necessary
for human serum production to include Pharmacokinetics (PK), Immune Response and Biomarkers.
The IC50 and other key kinetic constants were determined
for human serum BuChE inhibition by BNC, which proved to be a highly potent inhibitor in comparison to its structural analogue, cymserine.
Not exact matches
These findings call into question the safety of the recent substitution of DiNP
for DEHP in soft PVC, particularly since a shorter male AGD has been shown to be related to male genital birth defects in children (such as hypospadias and undescended testis) and impaired reproductive function in adult males (such as decreased fertility, impaired semen quality and lower
serum testosterone levels) and the fact that
human levels of DiNP are rapidly increasing globally, says Carl - Gustaf Bornehag, professor in Public Health Sciences at Karlstad University and responsible
for the current study.
If
serum is tested on
humans, it should be checked in advance that it can neutralize the virus, says Stephan Günther, a virologist at the Bernhard Nocht Institute
for Tropical Medicine, who is now in Nigeria.
Wet skin isn't the only challenge
for medical adhesives — the
human body is full of blood,
serum, and other fluids that complicate the repair of numerous internal injuries.
To assess cross-neutralization of TMAdV by known
human adenoviruses, 7 pools of in - house reference
sera at the VRDL (rabbit hyperimmune
sera) and collectively containing antibodies to
human adenovirus serotypes 1 through 35 were available
for testing.
To explore a potential link between the outbreak and associated illness in
humans, we blindly tested available
sera from titi monkeys (n = 59), rhesus macaques housed in the same building (n = 36), CNPRC personnel and close contacts (n = 20), and random
human blood donors (n = 81)
for evidence of recent or prior infection by TMAdV by virus neutralization (Fig. 6).
For the time course study, cells were treated with 20 μM of EGCG for 12, 24, 48, 72, or 144 h. Human colon cancer cell line HT - 29 and prostate cancer cell line PC3 were obtained from American Type Culture Collection (Manassas, VA), and were grown in McCoy's 5A and RPMI 1640 containing 10 % fetal bovine serum, respective
For the time course study, cells were treated with 20 μM of EGCG
for 12, 24, 48, 72, or 144 h. Human colon cancer cell line HT - 29 and prostate cancer cell line PC3 were obtained from American Type Culture Collection (Manassas, VA), and were grown in McCoy's 5A and RPMI 1640 containing 10 % fetal bovine serum, respective
for 12, 24, 48, 72, or 144 h.
Human colon cancer cell line HT - 29 and prostate cancer cell line PC3 were obtained from American Type Culture Collection (Manassas, VA), and were grown in McCoy's 5A and RPMI 1640 containing 10 % fetal bovine
serum, respectively.
GC - MS Based Metabolomics and NMR Spectroscopy Investigation of Food Intake Biomarkers
for Milk and Cheese in
Serum of Healthy
Humans — Alessia Trimigno — Metabolites
Inclusion Criteria: • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 • Have histologically or cytologically confirmed advanced or metastatic non-small cell lung cancer (NSCLC)(Stage IIIb or greater) • Measurable disease, as defined by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 • Known PD - L1 tumor status as determined by an immunohistochemistry (IHC) assay performed by the central laboratory on tissue obtained at Screening • A woman of childbearing potential must have a negative highly sensitive
serum (beta -
human chorionic gonadotropin [beta - hCG]-RRB- at Screening within 14 days prior to study drug administration Inclusion Criteria
for Crossover: • Participants must have been randomized to Arm A of the study and had radiographic disease progression according to RECIST 1.1 • Participants must have a mandatory biopsy at the time of disease progression according to RECIST 1.1 prior to crossing over.
Lack of cross-reactivity between the Bacillus thuringiensis derived protein Cry1F in maize grain and dust mite Der p 7 protein with
human sera positive
for Der p 7 - IgE.
Dr. Bovenkamp conducted further research at the Johns Hopkins University Bayview Proteomics Center in the Division of Cardiology at Johns Hopkins School of Medicine in Baltimore, Maryland, using proteomic techniques
for biomarker detection in
human serum.
The IgMs accounted
for essentially all of the misTTR hydrolytic activity of unfractionated
human serum.
Hu C et al. (2015) Autoantibody Profiling on
Human Proteome Microarray
for Biomarker Discovery in Cerebrospinal Fluid and
Sera of Neuropsychiatric Lupus.
The CDI HuProt microarray contains nearly 75 % of the
human proteome on a single glass slide, a unique and powerful tool
for high - throughput
serum profiling and biomarker discovery.
Human studies indicate that people with higher
serum D3 levels have a decreased risk
for falls and muscle weakness as well as less insulin resistance and diabetes.
For example, one has you tracking down microbes that allow the aliens to influence
human thought through telepathy so you can create a
serum that will stop the aliens from being able to enter
human minds, just as they did to President Whitmore (Pullman) in the first Independence Day.
When the brilliant Dr. Xavier (Ray Milland) concocts a
serum to improve
human sight, he stumbles upon a formula
for x-ray vision.
Serum lipase activity has been used
for the diagnosis of
human and canine pancreatitis
for several decades.
In
humans with blind intestinal loops constructed by radical bypass surgery, there is good evidence
for numbers as high as 1012 cfu / mL, and clinical consequences (eg, diarrhea, raised
serum folate, low
serum cobalamin) are well documented.
The mercury compound in vaccines is not only reasonably safe
for humans and animals, but it occurs in extremely small amounts and serves an important function — preventing bacteria from growing in the
serum.
Cats appear highly susceptible to cobalamin deficiency, partly as a result of the very rapid turnover of this vitamin compared with
humans.49 Cats with decreased
serum cobalamin concentrations should be supplemented with subcutaneously administered cobalamin at a dose of 1000 μg per cat once weekly
for 6 weeks, with reassessment of the
serum cobalamin concentration approximately one month after discontinuing therapy.
The world of
Sera is in a lengthy state of war as its
human inhabitants battle the Locust, a race of subterranean humanoids who launched into a conflicts that the
humans were ill prepared
for.