Sentences with phrase «for humans and mice»

(A — H) Learning curves for humans and mice in visible - target training (A and E) and hidden - target learning (B — D and F — H).

Enormous projects such as ENCODE (for humans and mice) or modENCODE (for other lab model systems, such as the fly Drosophila or the worm C. elegans) have been devoted to collecting these data in order to analyse and interpret them in the framework of genomic data and to form hypotheses about functions and relations.

«There's good reason to believe the rules will be the same» for human and mouse cells, says stem cell biologist Kevin Eggan of the Harvard Stem Cell Institute (HSCI).

He thinks the final count for both human and mouse will be «between 30,000 and 40,000 genes.»

For human and mouse they solved the equation for GL where they estimated ancestral genome size within a range similar to the extant human genome size.

Using Eq 2 and solving for GA with extant genome sizes from Table 1 and gain and loss rates calculated by the recent transposon method (Table 2), we get estimated ancestral genome sizes of 2.64 Gb and 2.66 Gb for human and mouse respectively.

Not exact matches

Studies have found that the additive increases risk of certain types of cancer in mice and the International Agency for Research on Cancer classifies byproduct 4 - Mel as «possibly carcinogenic to humans.»

Scientists know how to make fruit flies and mice smarter, and efforts to come up with a treatment for Alzheimer's and other neurological disorders are leading to drugs that enhance memory and cognition in humans.

a comment for you, a ufo picture who the fbi acredired as a real.pedrfo castillo who was teh one that sent me that noticie, i just did no much as put my mouse on that such an ufo, and sudendly something so i called part of human appeard.

It might mean - and most of the public attention has taken it to mean - an attempt to clone, gestate, and bring to term a human being, to do for human beings what has already been done for mice and for the lamb «Dolly.»

In order to determine the lethal toxic level of capsaicinoids in animals, and to extrapolate that level for humans, researchers in 1980 performed a rather gruesome experiment with mice, rats, guinea pigs and rabbits.

Hassles such as buying paper towels or searching for the perfect used car that used to require legwork, human interaction, and possibly even wearing pants can now be done with a click of a mouse from one's own living room.

Infant formula continues to evolve and there are patents already for implanting genes for making human milk in mice.

Dr. Issa's team made their discovery after first examining methylation patterns on DNA in blood collected from individuals of different ages for each of three species — mouse, monkey, and human.

The Salk team therefore took human brain organoids that had been growing in lab dishes for 31 to 50 days and implanted them into mouse brains (more than 200 so far) from which they had removed a tiny bit of tissue to make room.

Introducing human prostate cancer cell lines into mice, Wu and his colleagues saw a particular enzyme called MAOA activate a cascade of signals that made it easier for tumor cells to invade and grow in bone.

The mice behaved just like others of their kind, as far as scientists could tell, and they also looked the same — except for the human mini brain that had been implanted into each rodent's own cortex, made visible by a little clear cover replacing part of their skull.

«Our study shows that epigenetic drift, which is characterized by gains and losses in DNA methylation in the genome over time, occurs more rapidly in mice than in monkeys and more rapidly in monkeys than in humans,» explains Jean - Pierre Issa, MD, Director of the Fels Institute for Cancer Research at LKSOM, and senior investigator on the new study.

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

They seeded mice with human pancreatic tumours and then injected them daily with the souped - up bacteria for a week, giving them a week off before four more days of injections.

Shukla and colleagues discovered that a small drug molecule called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured human corneal cells, in donated human corneas, and in the corneas of mice infected with HSV - 1.

To test this hypothesis, Sigurdson and her team developed a transgenic mouse that expresses a prion protein that's identical to the human version — except for a small loop, which they swapped out for the elk prion sequence.

«We've been hearing about their potential for more than a decade, but the results have always been in mice and rats, and no one has shown they're safe or effective in humans long term,» says Robert Lanza of Advanced Cell Technology in Marlborough, Massachusetts, the company that carried out the stem cell intervention.

Human norovirus can't be grown easily in a lab, and for this reason, the researchers choose to study it in mice.

The researchers, reporting online March 5 in the American Journal of Reproductive Immunology, also say they found that an anti-inflammatory drug that is FDA - approved for rheumatoid arthritis and is believed to be safe for humans to take during pregnancy halted the brain injury in mouse offspring.

«So far, the drug has only been tested in mice, and while some research in human genetics suggests this approach could work in people too, we need more research before we know how relevant this could be for people with type 2 diabetes.»

Dr Luis Pedro Coelho, commented: «These findings suggest that dogs could be a better model for nutrition studies than pigs or mice and we could potentially use data from dogs to study the impact of diet on gut microbiota in humans, and humans could be a good model to study the nutrition of dogs.

Although the researchers emphasized that laboratory results involving cell lines and mice do not necessarily translate to human treatment, they say their findings show that new mTOR inhibitors combined with chemotherapy could become a new treatment strategy for T - ALL.

«Humans and mice: Similar enough for studying disease and different enough to give us new clues about evolution.»

«The mouse is one of the most utilised models for studying human biology and we use it for creating models of human illnesses and testing new drugs and therapies.

Several studies have supported a role for cancer stem cells in the aggressive brain tumors called glioblastoma, but those studies involved inducing human tumors to grow in mice, and as such their relevance to cancer in humans has been questioned.

The IGF1 protein is crucial for the growth of mammals, including mice and humans, so Ostrander's group and other collaborators began collecting DNA from additional breeds to see if they also shared the same gene variant.

More importantly, within the afflicted groups, both the mice and humans had similarly poor performance in the hidden target trials, making the Morris Maze Test a useful tool for comparing our two species, the researchers say.

Furthermore, the findings illustrate the fundamental importance of HYAL2 and hyaluronan turnover for normal human and mouse development.

CRISPR — Cas9 (or CRISPR, for short) has given scientists a powerful way to make precise changes to DNA — in microbes, plants, mice, dogs and even in human cells.

And for the past 20 years, scientists have assumed that the same is true in all mice and, therefore, in all humaAnd for the past 20 years, scientists have assumed that the same is true in all mice and, therefore, in all humaand, therefore, in all humans.

Concerned that the immune systems of clean mice might not be good proxies for the human immune system — no human is brought up in such clean conditions and fed such clean food — they housed lab mice with mice from a pet store.

In the quest for an animal model of PD that mimics motor and non-motor symptoms of human PD, scientists have developed strains of mice that overexpress α - synuclein.

Judy Anderson, a muscular dystrophy expert at the University of Manitoba in Winnipeg, Canada, adds that evidence for acetylcholine defects in human muscular dystrophy has been contradictory over the years, but if this preliminary finding holds up in mice and humans, it could pave the way for new drug targets.

To see if they would suffice to make H5N1 infection less severe, Webby and his co-workers injected mice with DNA for the neuraminidase gene from human H1N1, one of three flu subtypes covered by this winter's flu shot.

«No matter whether human being, mouse, whale or bacterium, nature does not constantly invent proteins for various living organisms anew, but varies them by evolutionary mutation and selection,» Alexander Schug of the Steinbuch Centre for Computing (SCC) says.

BO plays a role in mate selection among mice, and some experiments have suggested its importance for human mate selection as well (ScienceNOW, 18 June 2004).

Six pairs of mice — with one mouse engineered to produce gobs of human A-beta and one normal — were surgically joined for a year, causing blood mingling that's far more extensive than that of a blood transfusion.

Additionally, work in a mouse model revealed similar cells, indicating that the progenitors are conserved from mouse to human, and therefore, they must be «important cells with promising potential for cell therapy in treating liver disease,» explained Dr. Gouon - Evans.

All animals use the same enzyme to create the same methylation mark as a signal for gene repression, and her colleagues who study epigenetics in mice and humans are excited about the new findings, Strome said.

«For example, cancer research is heavily reliant on mouse models, and as a result we've become very good at curing mice, but that hasn't translated very well to humans.

Microbeads coated in a human egg protein work as a contraceptive in mice and could also be used to select the best sperm for IVF

A screen for mouse genes dependent on dHAND, a transcription factor implicated in neural crest development, identified Ufd1, which maps to human 22q11 and encodes a protein involved in degradation of ubiquitinated proteins.

«New type of antidepressant found to act quickly in mice: Compound already tested in humans for other purposes and found nontoxic.»

But as they push forward with the scientifically challenging transition from mice to monkeys and humans, they are setting the course for the future of infertility treatments — and perhaps even bolder experiments in reproduction.