Testing should be considered
for all individuals who are overweight or obese (BMI 25 or greater) plus the additional risks: first degree relative with diabetes mellitus or Polycystic Ovarian Disease, history of gestational diabetes, thyroid
disorder, HDL level < 35 mg / dl and / or Triglyceride level > 250 mg / dl,
hypertensive, sedentary, impaired glucose tolerance (IGT) or impaired fasting glucose (IFG) on previous testing, women who delivered macrosomic baby (e.g. weighing > 9 lbs), and other clinical conditions such as acanthosis nigricans, severe obesity, polycystic ovary syndrome, dyslipidemia.
Also, because many women with PCOS have hormonal imbalances and are overweight or obese, they are at higher risk
for miscarriage and complications such as gestational diabetes mellitus and
hypertensive disorders during pregnancy.