Sentences with phrase «for hypertriglyceridemia»
High triglyceride levels: Triglycerides ≥ 150 mg / dL (or receiving drug therapy for hypertriglyceridemia)
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Vascepa has been approved for use by the United States Food and Drug Administration (FDA) as an adjunct to diet to reduce triglyceride levels in adult patients with severe (≥ 500 mg / dL) hypertriglyceridemia.
The effect of Vascepa on the risk for pancreatitis and cardiovascular mortality and morbidity in patients with severe hypertriglyceridemia has not been determined.
«Decoding mechanisms opens the door to precise, individual interventions for the prevention of residual risk associated with the various causes of severe hypertriglyceridemia,» Dr. Gaudet said.
Last December, the same research team demonstrated blocking the expression of the gene that encodes apoC - III led to major relief of triglyceridemia in patients suffering a rare and extreme form of hypertriglyceridemia, which in turn opened the door for the identification of unexpected mechanisms that govern blood fat.
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LPL is a pivotal player in TG metabolism, as mutations in LPL or in its cofactors (ApoC - II, glycosylphosphatidylinositol - anchored high - density lipoprotein — binding protein 1, lipase maturation factor 1) account for the majority of monogenic hypertriglyceridemia cases (25).
Hypertriglyceridemia is an independent risk factor for cardiovascular disease, and plasma triglycerides (TGs) correlate strongly with plasma apolipoprotein C - III (ApoC - III) levels.
Use cautiously with high VLDL cholesterol, hypertriglyceridemia, or with a history of low blood pressure, coagulation disorders, potential for mania, or epilepsy.
However, far from encouraging people to consume unhealthy fats, this promising outcome may result in new therapeutic uses of Incas» peanut for the treatment of both hypertriglyceridemia and type 2 diabetes, as well as in new ways of preventing cardiovascular and metabolic diseases.
The addition of sacha inchi oil slowed down glucose production in 16 (38.1 %) participants that showed a higher concentration of triglycerides before meals (fasting hypertriglyceridemia), whereas an improved expression of sirtuin - 1 (SIRT1), a gene responsible for regulating energy within the cells and coordinating cellular functions, was registered four hours after ingesting the meal enriched with sacha inchi oil, and linked to lowered levels of blood sugar measured at the same time.
Management of hypertriglyceridemia includes counseling for lifestyle changes, such as weight control, dietary changes, and exercise.
NIDDM patients with hypertriglyceridemia who do not need to lose weight are candidates for a high - MUFA diet.