Sentences with phrase «for immune attack»

We would look at TPO, or Thyroid Peroxidase antibodies or anti thyroid globulin antibodies; we'll look for immune attack on the thyroid tissue.
«The danger flags that weren't there before now appear,» Chou says, «and that could make the cancer cells much easier targets for immune attack
In the body, MHCI proteins are watchdogs, tagging infected cells for immune attack.

Not exact matches

But there is little basis for assuming that he has not made such modification because he believes his position is «privileged» and thus immune from attack.
It not only helps to balance out the immune system functions but works as an anti-inflammatory to help calm down the systemic inflammation response in the body, for people like me, whose immune systems think it's a great idea to attack itself!
Unlike other autoimmune diseases, however, doctors know the trigger for coeliac disease: gluten, which provokes an immune response that causes the body to attack itself.
Following recommendations offered by CoopeTarrazú agronomists, Araya also prepared for a roya (coffee - leaf rust) attack, which has begun to affect once - immune altitude regions like Tarrazú — her farm is located at 5,250 f. (1,600 m) above sea level — due to global warming.
Simberg and colleagues also tried turning off the complement system — a facet of the immune system responsible for clearing microbes and damaged cells — thinking that this complement system might be attacking, transporting or otherwise accidentally pushing liposomes from blood to cells.
Previous research has suggested that antibodies — immune system proteins that can attack viruses — in a mother might be less effective against certain genetic variants of HIV - 1 in her body, thereby allowing for transmission of resistant viruses to her infant at delivery.
In the present study, the researchers have discovered a reason for reduced fertility in people with autoimmune polyendocrine syndrome type 1 (APS1), which increases the risk of developing autoimmune disease (caused by the immune system attacking and damaging healthy cells) and which is often used as a model for autoimmune disease in general.
For unknown reasons our immune system attacks healthy cells, tissues and organs in a process called autoimmunity, which can result in diseases such as multiple sclerosis, type 1 diabetes, lupus or rheumatoid arthritis.
He said that the most exciting arenas of immunology today include new strategies for vaccines and studies of regulatory T lymphocytes and the innate immune response, which is essentially the most general form of attacking pathogens.
Now her team has analysed the immune system's key controller genes for the first time and found that resistant devils have genes that equip them to attack the disease (Proceedings of the Royal Society B, DOI: 10.1098 / rspb.2009.2362).
Scientists have discovered the first example of a gene solely responsible for an autoimmune disease, a type of disorder in which the immune system attacks the body.
With little hope for Giese's survival, Rodney Willoughby, an infectious disease specialist at the Children's Hospital of Wisconsin in Milwaukee, induced a coma to protect her brain from viral attack, giving Giese's immune system time to rev up to combat the virus.
Immunotherapy is an emerging field in the global fight against cancer, even though scientists and clinicians have been working for decades to find ways to help the body's immune system detect and attack cancerous cells.
Working with human immune cells in the laboratory, Johns Hopkins researchers report they have identified a critical cellular «off» switch for the inflammatory immune response that contributes to lung - constricting asthma attacks.
Although some cancers — particularly those that are rife with mutations like lung cancer or melanoma — create more tangible targets on the surface of cells for the immune system to recognize and attack, other malignancies such as prostate and pancreatic cancers have proved more intransigent.
In the hunt for genetic and environmental factors responsible for allergies, a prime suspect has been interleukin - 4 (IL - 4); this immune system protein tells white blood cells to make IgE antibodies, which recognize foreign substances and set off an immune attack.
This made it possible for their immune systems to produce sufficient amounts of CD8 T cells that were primed to attack and kill HIV - infected cells.
Immune therapy for ovarian, breast and colorectal cancer — treatments that encourage the immune system to attack cancer cells as the foreign invaders they are — has so far had limited success, primarily because the immune system often can't destroy the cancer cells.
It has been understood for several years that, in patients suffering from this disease, immune cells attack the aquaporin - 4 water channel of the brain cells.
The immune system can, for example, dispatch «regulatory» cells that suppress immune attacks against self.
These types of allergies occur when the body's immune system mistakes a harmless food protein for a threat and attacks it as it would normally do with a bacterium or a virus.
Two key experiments demonstrated this necessary and sufficient role for the activated T - cells, which presumably attack heart muscle tissue in an auto - immune fashion.
Rather than waiting for an infected person's immune system to produce noticeable amounts of antibodies, the team chose to home in on the bacteria itself — specifically, proteins the bug sheds when attacked by the body's defenses.
Autoimmune diseases result when the immune system mistakes some of the body's proteins for invaders and attacks organs.
By injecting cowpox antigens into his patients» bloodstream, for instance, Jenner primed their immune systems to attack the similar smallpox virus.
In some people, the immune system has a disconcerting tendency to revolt: For some reason, it viciously attacks the body itself.
Historically, clinicians evaluating a patient for transplant have sought to identify donor cells that are perfectly matched to the patient's cell type, which is considered to be the optimal approach to help ensure successful outcomes and to minimize risk of graft - versus - host disease (GVHD), a serious and potentially life - threatening complication that occurs when the donated immune cells attack the patient's cells as foreign tissue.
But if the immune system is indeed attacking the corneal protein identified by the Cantor group, the discovery could «in principle allow us to disrupt or arrest this component» of the attack, says M. Reza Dana, an ophthalmologist and ocular immunologist at Harvard Medical School, perhaps by inactivating the specific set of immune cells responsible for it.
Melton said that the device Anderson and his colleagues at MIT are currently testing has thus far protected beta cells implanted in mice from immune attack for many months.
This form of interference with bacterial gene regulation is also of pharmaceutical interest as it is known that pathogenic bacteria can protect themselves against attack by the immune system and the effect of antibiotics by forming biofilms, for instance on the epithelium of the respiratory system.
For example, they produce proteins called cytokines that tell infection - fighting immune cells to back off and recruit «suppressor» cells directly from the bone marrow that help cancel the immune attack.
This approach could be especially useful for delivering HIV vaccines and for stimulating the body's immune system to attack tumors, says Irvine, who is also a member of MIT's Koch Institute for Integrative Cancer Research.
They may have kept your mother's immune system from attacking you in utero, for instance.
The researchers are now looking at how ICOS signals can be altered to diminish autoimmune disorders and augmented for more effective vaccine development, and are beginning research on how ICOS signaling may benefit Chimeric Antigen Receptor - T cell (CAR - T) therapies, which involves engineering of patient's own immune cells to recognize and attack their cancers.
Tumors escape from the fighter T - cells that would otherwise attack them, by tricking the immune system and making an environment ripe for tumor growth.
«We hope to use these findings to make the immune response to vaccines and infections faster and more productive, and slower and less active for autoimmune conditions where the body attacks itself,» Professor Vinuesa said.
The immune system is responsible for protecting the host from foreign pathogens; however, there are many diseases — known as autoimmune diseases — that result from the immune system attacking the host.
For a malignant tumor to form, cancer cells must evade the immune system's attack.
Following a tissue graft transplant — such as that of the face, hand, arm or leg — it is standard for doctors to immediately give transplant recipients immunosuppressant drugs to prevent their body's immune system from rejecting and attacking the new body part.
Estes, who works with virologist Jeffrey Lifson, has also developed a DNAscope to visualize this HIV DNA — called the provirus — which becomes integrated into human cells and can persist for decades without being attacked by the immune system or antiretroviral (ARV) drugs.
The end result was that the plants» immune systems were even more prepared for fungal attack in the morning but more susceptible to infection at night — presumably to minimize interference between pathogen defense and growth, which mainly occurs in the pre-dawn hours.
Tumor cells often secrete chemicals that suppress the immune system, making it difficult for the body to attack tumors on its own.
Scientists at Helmholtz Zentrum München, partner in the German Center for Diabetes Research, and their colleagues at Technical University of Munich have now reported in the journal PNAS about a mechanism used by the immune system to prepare for this attack.
Zika was known for 60 years as a mild virus that appeared sporadically, but since 2007, two troubling shifts have taken place, Dye said: Zika virus now results in widespread outbreaks of hundreds or thousands of cases, and it is associated with neurological disorders like microcephaly and Guillain - Barre syndrome, a disorder in which the body's immune system attacks the nerves.
«Gene circuit switches on inside cancer cells, triggers immune attack: Advance may open new pathways for cancer immunotherapy.»
Certain molecules on tumors can serve as targets for attack by cells of the immune system.
In a first for gene therapy, researchers have successfully treated cancer patients by genetically modifying their immune cells to attack tumors.
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