Sentences with phrase «for infectivity»

Env clones with inserts in the correct orientation screened for infectivity by cotransfection with an env deficient HIV - 1 (SG3env) backbone in 293T cells

Env clones with inserts in the correct orientation screened for infectivity by co-transfection with an env deficient HIV - 1 (SG3env) backbone in 293T cells

But because the prion hypothesis violates long - standing dogma that a DNA - or RNA - based genome is needed for infectivity, doubters insist that it is not yet proven: A virus or some other as - yet - unidentified microbe, they say, may team up with the prion protein to devastate the nervous system.

The low dose required for infectivity and the severity of the disease it causes had led the Centers for Disease Control and Prevention to classify F. tularensis as a Category A bioterrorism agent, and to track tularemia cases nationwide, according to Dr. Brook Peterson, a senior scientist at the UW School of Medicine who also participated in the study.

Not exact matches

In collaboration with many researchers (graduate students, postdocs, and faculty elsewhere), we have examined the role of cross-immunity on the evolution and dynamics of influenza; the impact of behavioral changes, long periods of infectiousness, variable infectivity, co-infections, prostitution, social networks, and vaccine efficacy on HIV dynamics; the role of exogenous re-infection, variable progression rates, vaccination, public transportation, close and casual contacts on tuberculosis dynamics and control; the impact of life - history vector dynamics on dengue epidemics; and on the identification of time - response scales for epidemics of foot and mouth disease.

For example, their surface is covered by glycoconjugates that are essential for their survival and infectivity, but little is known of the processes that lead to the synthesis of such moleculFor example, their surface is covered by glycoconjugates that are essential for their survival and infectivity, but little is known of the processes that lead to the synthesis of such moleculfor their survival and infectivity, but little is known of the processes that lead to the synthesis of such molecules.

Since then, prisons have changed and the notorious policy of Viral Infectivity Restrictions (VIR), which was singled out for particularly fierce criticism in the report, has been abandoned.

They find statistical support for high viral infectivity rates of dengue serotypes 2 and 3 relative to dengue 1.

Investigators also have a variety of specialized resources for testing virus infectivity in various bugs and animals, sequencing viral genes and imaging pathogen structures.

It is thought that the ability of misfolded prion protein to serve as a nucleus for the misfolding and aggregation of the host prion protein is the key property responsible for prion replication and infectivity (Soto et al., 2006; Soto, 2012).

Genetic markers of infectivity or likelihood of being a super-spreader could be used to justify quarantine and isolation policies, with the concomitant implications for individual liberty.

Strategies for the clinical management and public health control of different infectious diseases vary depending on the acuteness and chronicity of infection, infectivity and virulence of the causative pathogen, modes and ease of transmission, and whether there are effective treatments, vaccines, or other means of prevention.

«Our study shows for the first time exactly how immune cells sense the virus and how the virus uses one of its proteins to tune its stealthiness and infectivity,» says senior study author Nicolas Manel of the Institut Curie.

According to lead author Tim Straub, «Scientists have been trying to get an infectivity assay for the human noroviruses going for about 30 years now, and we are truly the first.

Identification and characterization of PWWP domain residues critical for LEDGF / p75 chromatin binding and human immunodeficiency virus type 1 infectivity.

A different viral envelope protein (Env), usually from VSV - G due to wide infectivity, is often used as a substitute for HIV - 1 Env, which can only infect CD4 + cells.

Lentiviral particles with the VSV - G envelope have high infectivity in a wide range of cell types, so they're ideal for work with primary cells or other difficult - to - transfect cells.

Nonhuman and human primates are generally considered «dead end» hosts, so adaptation in this host may engender a phenotype of reduced infectivity for subsequent hosts; this is likely an uncontrollable characteristic of the model system, rather than an indication of the viability of the spirochetes.

BB0844, an RpoS - Regulated Protein, Is Dispensable for Borrelia burgdorferi Infectivity and Maintenance in the Mouse - Tick Infectious Cycle

Piesman (23, 24) and Crippa et al. (25) showed that tick - derived spirochetes are physiologically different from culture - derived spirochetes and that infectivity for mice is enhanced with a tick - derived inoculum.

Infectivity in Chimpanzees (Pan troglodytes) of Plasma Collected before HCV RNA Detectability by FDA - Licensed Assays: Implications for Transfusion Safety and HCV Infection Outcomes.

The limited infectivity of persisting non-cultivable B. burgdorferi has no biological significance for the natural enzootic cycle of B. burgdorferi, but it remains to be determined if they have significance in the post-treatment host.

Across populations, kiwi is used in the preparation of antimicrobial products to reduce the development of resistance towards the conventional medications for fungal and bacterial infectivity.

As for the alleged predisposition of a given ethnicity to an exacting ailment, augmented vulnerability to infectivity, etc., such qualities, in general, don't demonstrate an «ethnic» nature, but are associated with societal, enlightening and extra living conditions, the closeness of hot spots of contamination, the grade of adaptation during immigration, and all that.

However, the Court's declaration of invalidity, unenforceability and infectivity is suspended for a period of one year (January 24, 2015), to allow the government time to modify the law.