«It has only recently been discovered that the innate immune system has a form of memory», explains Eicke Latz, Director of the Institute
for Innate Immunity of the University of Bonn.
A shared role for RBF1 and dCAP - D3 in the regulation of transcription with consequences
for innate immunity.
«The study by Egli et al. holds promise for enhancing the response of the seasonal influenza vaccine by blocking the receptor used
for the innate immunity signalling molecule IL28B.
To test the role of innate immune response in the mouse model of ALS, the researchers focused on Toll - like receptors (TLR), which are important sensors
for innate immunity.
«Our compound has an antiviral effect against all these viruses,» said Michael Gale Jr., University of Washington professor of immunology and director of the UW Center
for Innate Immunity and Immune Disease.
Not exact matches
IDEAYA is pioneering the next generation of biomarker - enabled synthetic lethality therapies
for genetically defined patient populations and advancing an immuno - oncology pipeline targeting immuno - metabolism and
innate immunity.
Key
for athletes is, adequate vitamin D levels promote good bone density,
innate immunity, muscle wasting, and exercise - related inflammation and
immunity.
These investigations revealed little change over long periods of time
for some
innate -
immunity genes, providing evidence of strong constraints.
«We found that interbreeding with archaic humans — the Neanderthals and Denisovans — has influenced the genetic diversity in present - day genomes at three
innate immunity genes belonging to the human Toll - like - receptor family,» says Janet Kelso of the Max Planck Institute
for Evolutionary Anthropology in Leipzig, Germany.
Town and others have proposed a second, newer theory
for harnessing microglia and the
innate immunity to fight Alzheimer's.
Focusing on basic research
for the functional regulation of
innate and adaptive
immunity and on translational research
for cancer immunotherapies, the National Key Laboratory of Medical Immunology has been conducting innovative research and exploration, and is becoming a rising star in the international immunology community.
Looking
for an answer, Emerman and colleagues homed in on the immune protein TRIM5α, one of several proteins involved in
innate immunity, the body's first line of defense against viral infection.
Pinpointing the origins of gamma - ray bursts, determining the workings of
innate immunity, and extending the use of differential equations to applications in relativity are achievements paying off in Shaw Prizes
for the scientists involved.
«The current study reveals the new roles of
innate immunity in ALS pathomechanism and provides a clue to develop a new therapeutic approach
for protecting ALS motor neurons.»
Zhijian «James» Chen, Ph.D., has received the 2018 Lurie Prize in Biomedical Sciences
for his discovery of the cGAS enzyme, a sensor of
innate immunity.
The alpha2 beta1 integrin provides a co-stimulatory signal required
for mast cell activation, cytokine secretion and initiation of
innate immunity.
Register now
for the 11th International Conference on
Innate Immunity to be held at the Royal Olympian Hotel in Olympia, Greece, from June 1 - 6, 2014.
A research team from the German Leibniz Institute
for Zoo and Wildlife Research (IZW) recently discovered that cheetahs have developed a very efficient
innate «first line of defence»
immunity to compensate potential deficiencies in other components of their immune system.
Our current work defines one more component of a specific branch of
innate immunity responsible
for the recognition and clearance of senescent cells and presumably involved in keeping us young.
Foreign researchers honored as the 31st KIA laureates include: Prof. Eric Vivier (France)
for his research on harnessing
innate immunity against cancer; Prof. Jianfang Wang (Hong Kong, China)
for his research on Colloidal Plasmonic Metal Nanocrystals; Prof. Majed Chergui (Switzerland)
for his research on unravelling the fundamentals of solar; Prof. Katharina Gaus (Australia)
for her research on Single molecule imaging of T cell receptor signaling; and Prof. Dr. Burkhard Büdel (Germany)
for his research on Role of lichens and cyanobacteria in biological soil crusts.
Areas
for future focus will be to develop mechanisms of boosting host defence and
innate immunity so antivirals / antibacterials will be less required.
More investment into research is all the more important given that we are close to formidable breakthroughs in many areas of respiratory diseases, such as molecular bacteriology and virology, development of vaccines and antiviral agents, boosting host defence and
innate immunity, molecular pathology and personalised care
for lung cancer.
Long - time readers of this blog will not be surprised to hear that animal research has featured prominently in the work
for which this year's winners of the Nobel Prize in Physiology or Medicine are being honoured - Bruce A. Beutler and Jules A. Hoffmann
for their
for their discoveries concerning the activation of
innate immunity, and... Continue reading Nobel Prize 2011: Flies and mice take a bow!
In 2011, two scientists were awarded the 2011 Nobel Prize in Physiology or Medicine
for identifying receptor proteins, named Toll - like receptors, that recognize these microorganisms and activate
innate immunity, the body's first line of defense.
Thank you
for submitting your article «Mechanism of
innate - like lymphocyte surveillance of the subcapsular sinus to provide lymph node barrier
immunity»
for consideration by eLife.
The macrophages release cytokines that can activate more
innate immune cells, readying them
for attack on viruses or cancer cells, or they can activate the adaptive arm of
immunity, priming it
for clonal expansion.
Natural Killer Cells - composed of
innate immunity and are responsible
for helping to fight tunours and cells that are infected with viruses
There is also a particular need
for replication and extension of our finding that greater protective parenting was associated with a significant shift in cell - type composition in the direction of relatively fewer CD14 monocytes (a marker of
innate immunity), suggesting potential long - term impact on chronic inflammation (Irwin and Cole, 2011).