Inducible cutaneous inflammation reveals a protumorigenic role
for keratinocyte CXCR2 in skin carcinogenesis.
New results from a clinical trial involving more than 900 military veterans at high risk
for keratinocyte carcinoma skin cancer provides evidence that using the generic skin cream fluorouacil 5 percent for two to four weeks may reduce the risk of a squamous cell carcinoma (SCC) needing surgery by 75 percent within a year.
Not exact matches
When the
keratinocytes treated with all six cytokines expressed significantly more genes than one of the lacking combinations, it meant that the lacking cytokine was playing an influential role
for the expression of those genes.
For example, earlier research suggested that Neanderthal DNA influenced skin cells known as
keratinocytes that help protect the skin from environmental damage such as ultraviolet radiation and germs.
«This «cross-talk» between skin - resident T cells and nearby
keratinocytes is critical
for re-establishing the skin barrier following wounding,» MacLeod said.
The scientists found that celecoxib directly increased stem cell differentiation into
keratinocytes — skin cells required
for wound healing.
Cell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest
for the replacement of the defective cell population from the patient (the striatal neurons
for Huntington's disease, the cells of the retinal pigment epithelium
for retinitis pigmentosa,
keratinocytes for genodermatoses, etc.).
Now, of course, that is perhaps valid
for if you only test these facts, and Dean asks, actually, whether there will be any other factor combinations that would allow reprogramming of
keratinocytes?
Unlimited source of
keratinocytes and melanocytes derived from pluripotent stem cell
for epidermis cell therapy
This includes the enzymatic machinery required
for production and functional delivery of melanosomes to
keratinocytes.
For the expansion and differentiation of human keratinocyte stem cells for permanent skin restoration in victims of extensive bur
For the expansion and differentiation of human
keratinocyte stem cells
for permanent skin restoration in victims of extensive bur
for permanent skin restoration in victims of extensive burns.
Induction of GITRL expression in human
keratinocytes by Th2 cytokines and TNF - α: implications
for atopic dermatitis.
For the first set of experiments, first author Trond Aasen, Ph.D., a postdoctoral researcher at the Center of Regenerative Medicine in Barcelona, used viral vectors to slip the genes for the master regulators Oct4, Sox2, as well as Klf4 and c - Myc into keratinocytes cultured from human skin explan
For the first set of experiments, first author Trond Aasen, Ph.D., a postdoctoral researcher at the Center of Regenerative Medicine in Barcelona, used viral vectors to slip the genes
for the master regulators Oct4, Sox2, as well as Klf4 and c - Myc into keratinocytes cultured from human skin explan
for the master regulators Oct4, Sox2, as well as Klf4 and c - Myc into
keratinocytes cultured from human skin explants.
Comparative analysis of canine dermatophytosis and superficial pemphigus
for the prevalence of dermatophytes and acantholytic
keratinocytes: a histopathologic and clinical retrospective study.
Firstly, 27 nutritional components were screened in vitro
for their ability to up - regulate epidermal lipid synthesis, using cultured canine
keratinocytes (Watson et al. 2006).