Sentences with phrase «for lack of efficacy»

Twelve percent withdrew from the study for lack of efficacy.

Not exact matches

Topics included: early reporting on inaccuracies in the articles of The New York Times's Judith Miller that built support for the invasion of Iraq; the media campaign to destroy UN chief Kofi Annan and undermine confidence in multilateral solutions; revelations by George Bush's biographer that as far back as 1999 then - presidential candidate Bush already spoke of wanting to invade Iraq; the real reason Bush was grounded during his National Guard days — as recounted by the widow of the pilot who replaced him; an article published throughout the world that highlighted the West's lack of resolve to seriously pursue the genocidal fugitive Bosnian Serb leader Radovan Karadzic, responsible for the largest number of European civilian deaths since World War II; several investigations of allegations by former members concerning the practices of Scientology; corruption in the leadership of the nation's largest police union; a well - connected humanitarian relief organization operating as a cover for unauthorized US covert intervention abroad; detailed evidence that a powerful congressional critic of Bill Clinton and Al Gore for financial irregularities and personal improprieties had his own track record of far more serious transgressions; a look at the practices and values of top Democratic operative and the clients they represent when out of power in Washington; the murky international interests that fueled both George W. Bush's and Hillary Clinton's presidential campaigns; the efficacy of various proposed solutions to the failed war on drugs; the poor - quality televised news program for teens (with lots of advertising) that has quietly seeped into many of America's public schools; an early exploration of deceptive practices by the credit card industry; a study of ecosystem destruction in Irian Jaya, one of the world's last substantial rain forests.

Not only should clinicians consider the lack of evidence supporting the efficacy of rACTH, but its story should cause us to reexamine and strengthen our standards for FDA approval, Medicare and private insurance coverage, and professional use patterns.»

The limitations of macroprudential policies reflect the potential for risks to emerge outside sectors subject to regulation, the potential for supervision and regulation to miss emerging risks, the uncertain efficacy of new macroprudential tools such as a countercyclical capital buffer, and the potential for such policy steps to be delayed or to lack public support.14 Given such limitations, adjustments in monetary policy may, at times, be needed to curb risks to financial stability.15

Lack of efficacy of thickened feeding as treatment for gastroesophageal reflux.

Conventional drug discovery remains a hit - and - miss affair and Hunter believes the 50 percent failure rates seen for experimental compounds in mid - and late - stage clinical trials due to lack of efficacy is unsustainable, forcing a shift to AI.

«Additional studies should certainly be considered, but we hope that medical professionals will consider the positive potential of honey as a treatment given the lack of proven efficacy, expense and potential for adverse effects associated with the use of DM,» said lead study author Ian Paul, a pediatrician and associate professor of pediatrics.

«Despite the increased quality risks and the lack of safety and efficacy data for non-FDA regulated custom - compounded bioidentical hormones, their use by menopausal women is higher than expected and appears to be continuing to grow,» said lead researcher JoAnn Pinkerton, MD, a professor of obstetrics and gynecology at the University of Virginia Health System, Charlottesville.

The researchers found that military sexual assault training is often lacking in content and efficacy, especially in the eyes of personnel for whom it is most relevant.

Medical professional societies and clinical researchers advocated for the policy based on the available literature on FMT's safety and efficacy and the lack of treatment alternatives for this patient population.

«Using proteins that are found on the surface of bacterial cells as the basis for vaccination may lack efficacy because of the variability of the exact protein structure,» says Mobley.

There is evidence that rTMS is safe and not associated with any adverse events, but given the variability in technique and outcome reporting that prevented meta - analysis, the evidence for efficacy of rTMS for seizure reduction is still lacking despite reasonable evidence that it is effective at reducing epileptiform discharges.

Structured Abstract Introduction: The analysis of pharmaceutical industry data indicates that the major reason for drug candidates failing in late stage clinical development is lack of efficacy, with a high proportion of these due to erroneous hypotheses about target to disease linkage.

Another 2015 review cites «inconsistent / weak evidence» for flossing and a «lack of efficacy.»

With direct proof of serotonin deficiency in any mental disorder lacking, the claimed efficacy of SSRIs is often cited as indirect support for the serotonin hypothesis... The fact that aspirin cures headaches does not prove that headaches are due to low levels of aspirin in the brain.

Persistent hunger and irritability noted in non-obese men and women in earlier IER trials, where food was completely restricted on alternate days, suggest that some individuals are unlikely to be able to comply for extended periods of time.33 Compliance with IER protocols which allow some intake on restricted days have been promisingly high.38, 43, 48, 49, 51, 52 Additionally, several studies have also demonstrated a lack of compensatory hyperphagia 38, 39, 41, 48, 52, 84 upon resumption of free - eating which, if were to occur, would be expected to limit the efficacy of IER as a weight loss / maintenance strategy.

Beyond efficacy, safety data are critical for the therapeutic application of fasting but are sorely lacking.

But then one would recall that other public functions exist, such as health, transportation, and higher education, that make large and urgent claims on the budgets of state governments; that problems other than a lack of money afflict the schools, such as students who arrive unprepared for learning or life in a classroom; and that evidence for the efficacy of money per se is at best mixed.

The lack of preparation and support affect teachers» beliefs in their ability to do the job they are hired for — in other words, their teacher efficacy (Wolfolk - Hoy, 2000).

It lacks the theater of AMG V8s, but for efficacy it can't really be faulted.

Other vaccinations outlined in the chart above are usually not needed or recommended in most ages of pets for either lack of efficacy or safety reasons.

While we have been having fewer problems in our area with the «lack of efficacy», when I talk to people south of us, the problem hasn't gone away for them.

There is now reasonably consistent evidence that populism thrives on people's feeling of a lack of political efficacy, a belief that the world is unfair and that they do not get what they deserve, and that the world is changing too quickly for them to retain control.

If the approach in Armstrong and Cochrane is followed in the future, it seems unlikely that courts will order that the government pay for experimental treatments that lack at least some evidence of medical efficacy.

However, the lack of extra funding for its implementation raises questions over its likely efficacy.

Despite the fact that Hispanic (eighth grade) adolescents have the highest lifetime drug - use prevalence rates across all major illicit drugs (except amphetamines)(Johnston, O'Malley, Bachman, & Schulenberg, 2005), and Hispanic high school students have the highest rates of unprotected sex at last intercourse (CDC - P, 2004b) compared to African American and non-Hispanic Whites, research on the efficacy of drug abuse and HIV prevention programs for Hispanics is lacking (González - Castro et al., 2003).