The researchers, using $ 200,000 in seed money from the University of Washington, plan to use pets, not laboratory animals, for the initial study, and recruit volunteer dogs — or at least dogs whose owners volunteer them —
for larger scale studies in the future.
The European consortium
for this larger scale study, which will be led from Spain by the CNIC, is already being formed, and includes researchers from Belgium, the Netherlands, Germany, France, Denmark, Serbia, Poland, Sweden, and the United Kingdom.
Not exact matches
While the new mid-stage
study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even
for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a
large scale in the developing world.
Using data from a
large -
scale study that tracked participants» diet and health information
for more than a decade, researchers found an association between moderate chocolate consumption and a lowered risk
for atrial fibrillation.
Page said that even in a best case scenario, a male birth control pill
for consumers is still between five and 10 years away, since much
larger -
scale studies need to be done before the FDA would give a seal of approval.
And the giant that makes the platform he's building on, Apple,
for example, is running
large -
scale medical
studies using its software, and is said to be looking to handle clinical data as the first step to a real attempt to break into the medical market.
Reputable,
large -
scale studies demonstrate that natural - duration breastfeeding suppresses a return to fertility
for an average of 14 months post-partum
for most first - world women.
A
large -
scale scholarship system targeted at students from Asia
for graduate level
study in science and engineering fields would be one idea
for adding to the skilled workforce in both Australia and the students» home countries.
For example, while we have not seen any
large -
scale research
studies in this regard, we would predict that crimini mushrooms grown on composted materials that had previously been contaminated with residues of pesticides, heavy metals, or other unwanted substances would end up absorbing some of these contaminants into the brown button mushroom that we eat.
These were
large scale, well done observational
studies that were corrected as well as humanly possible
for confounders.
Researchers hope the new
study «will establish
large -
scale test norms and expected ranges of pre-competition scores
for this age group, and will further investigate the capacity
for K - D scores to capture closed head injury and concussion.»
Co-author of the
study Mary Renfrew, Professor of Mother and Infant Health at the University of Dundee, said: «This is the first
large -
scale study to show an increase in breastfeeding in communities where rates have been low
for generations, and where it can be particularly difficult
for women to breastfeed without strong family and community support, because of strong societal barriers.
The most recent
large scale study comparing outcomes
for mother and baby reported in the British Medical Journal last month showed that
for women who had previously given birth, adverse outcomes were less common among planned home births (1 per 1,000) than among planned hospital births (2.3 per 1,000).
They also found that some of the athletes, none of whom suffered diagnosed concussions, didn't do as well as predicted on tests of learning and memory at the end of the season, although the
study did not find «
large -
scale, systemic differences» in the brain scan measures, which the authors found «somewhat reassuring» and consistent with the fact that millions of athletes play contact sports
for many years without developing progressive neurodegenerative disorders.
(As I point out in the book, a recent
study by the National Center
for Education Research found that none of the many
large -
scale character - education programs in use in American schools produces any significant positive outcomes.)
Furthermore, there has been no
large -
scale study of the impact of this intervention on breastfeeding initiation and duration, although a
study based in Scotland has provided some evidence
for an association between birth in a Baby Friendly facility and increased rates of breastfeeding at 1 week of age.16, 17
They don't even include any references to the
large -
scale studies in Canada [6] and the Netherlands [7] that has found no increased risk
for homebirth versus hospital birth and one US
study looking at an integrated system (like those in Canada and the Netherlands) found the same outcome [8](nudge, nudge, USA).
And in fact, a
larger -
scale study suggests that simply implementing a bedtime routine without any behavioural interventions
for infants can have significant positive effects
for the sleep of the baby and the parents» well - being [8].
«Protein in breast milk reduces infection risk in premature infants:
Study shows need
for large -
scale trial of lactoferrin's role in immune system development.»
Physical punishment is associated with a range of mental health problems in children, youth and adults, including depression, unhappiness, anxiety, feelings of hopelessness, use of drugs and alcohol, and general psychological maladjustment.26 — 29 These relationships may be mediated by disruptions in parent — child attachment resulting from pain inflicted by a caregiver, 30,31 by increased levels of cortisol32 or by chemical disruption of the brain's mechanism
for regulating stress.33 Researchers are also finding that physical punishment is linked to slower cognitive development and adversely affects academic achievement.34 These findings come from
large longitudinal
studies that control
for a wide range of potential confounders.35 Intriguing results are now emerging from neuroimaging
studies, which suggest that physical punishment may reduce the volume of the brain's grey matter in areas associated with performance on the Wechsler Adult Intelligence
Scale, third edition (WAIS - III).36 In addition, physical punishment can cause alterations in the dopaminergic regions associated with vulnerability to the abuse of drugs and alcohol.37
The results of this
large -
scale study are very reassuring as they confirm that current NICE guidance1, which recommends annual mammograms
for women over 40 who are at an increased risk of breast cancer, is effective.
Neighborhoods that are being
studied for the first wave of
larger -
scale rezoning and affordable housing development under de Blasio's plan:
Low levels of physical activity and inefficient sleep patterns intensify the effects of genetic risk factors
for obesity, according to results of a
large -
scale study presented at the American Society of Human Genetics (ASHG) 2017 Annual Meeting in Orlando, Fla..
Researchers began this work at the Perelman School of Medicine at the University of Pennsylvania, which led to a
large -
scale, multi-year
study in connection with the Plikus Laboratory
for Developmental and Regenerative Biology at the University of California, Irvine.
«Previous
studies looked
for turbulence or eddies on the
scale of the animals» size,» he says, instead of
large downward jets.
Such highly sensitive in vitro techniques permit the use of picomole quantities of an antigen in partially purified preparations
for the isolation of monoclonal antibodies, which can in turn be used in biological
studies and in immunochemical procedures
for large -
scale purification and isolation of that antigen.
The
study does not rule out the possibility that
large -
scale organic operations eventually will reduce greenhouse gas emissions, but,
for now, McGee said, higher emissions are likely to continue unless actions are taken to correct course.
The
study was a collaboration with IBM and offers a
large -
scale survey of the commonly used container management framework known as Docker, a platform that facilitates the deployment of microservices by providing a registry service that acts as a central repository
for software components focusing on specific functionalities called images.
While
large -
scale climate research models offer a systems view of what the transport sector,
for example, could contribute to climate protection in comparison to the energy sector, the
study presented in Science, however, examines transport - related issues within the sector by using more recent and more specific data on how people commute and travel.
«More broadly, seismic surveys
for oilfield exploration or earthquake investigations tend to rely on length
scales that are usually much
larger than those used by our
study,» she added.
But Smith also stressed the need
for a much
larger -
scale study.
Carleton University geoscientist Richard Ernst, who has
studied LIPs
for two decades, launched a
large -
scale effort in 2010 to find answers.
This emphasises the need
for a much
larger scale, prospective
study,» he told New Scientist.
A
large -
scale genetic
study of the links between telomere length and risk
for five common cancers finds that long telomeres are associated with an increased risk of lung adenocarcinoma.
A budget of $ 1 million per year
for 5 years precludes a
large -
scale study or extensive data collection, he says.
To maintain its foothold in
large -
scale, world - class research, Japan has launched its own Brain Mapping by Integrated Neurotechnologies
for Disease
Studies (Brain / MINDS) project, in line with the increasing interest in brain - mapping projects around the world, such as the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative project in the United States and the Human Brain Project (HBP) in Europe.
For example, the results of one
study, known as UPLIFT, one of four
large -
scale studies conducted in 2008, demonstrated the effectiveness and safety of a drug called Spirivain about 6,000 patients with respiratory disease.
The snow algae specialist comments on the
study: «
For the first time ever, researchers have investigated the
large -
scale effect of microorganisms on the melting of snow and ice the Arctic.»
In addition to
studying the material and its effectiveness, the team wanted to determine how to best
scale up the new filtration material so it would be viable
for large -
scale operations at power plants.
Now it's time to do a
larger -
scale study, particularly in high - risk populations, and follow participants» progress
for longer periods, Dong and Raed say.
The U.K.
study recommends prohibiting
large -
scale release of nanoparticles
for remediation purposes «until it can be shown that the net benefits exceed the risks,» says Dowling.
The
larger scale Cancer Genome Atlas
study provided the information needed to alter proteins or RNA sequences that may act as «drivers»
for prognostic biomarkers or therapeutic targets.
«It is unlikely that historically low rates of deforestation can persist in the face of growing pressures to clear land due to increases in population, demand
for wood and charcoal, cropping with reduced fallow periods leading to soil degradation, and international interests in
large scale land investments
for oil, biofuel and other crops,» the
study states.
For those who aren't familiar with it, the «tipping point» is a concept from epidemiology (popularized by the best - selling book by Malcolm Gladwell) that suggests that small changes accumulate innocuously until a critical mass is reached, at which point a
large -
scale, irreversible change occurs in the system under
study.
It represents the first
large scale study of individuals seeking treatment
for gambling problems in the UK, at a time when this disorder is being re-classified alongside drug addiction as the first «behavioural addiction».
«We don't know what exposure is leading to this susceptibility to dietary glutamate, but this pilot
study suggests the need
for a
large -
scale clinical trial, since dietary change could be an effective low - cost treatment option
for developing countries.»
«Our
study shows that it would be relatively cheap to secure the future of the forest — and protect its plants, birds and other animals — by paying land owners on a
large scale to set aside land
for conservation.
«Asantha developed an idea
for studying galaxies by measuring their
large -
scale structure.
For example, this could support
large -
scale epidemiologic
studies or remote pharmacological trials,» said senior and corresponding author David L. Kaplan, Ph.D., Stern Family Professor in the Department of Biomedical Engineering at Tufts School of Engineering.
«These data were originally taken
for a completely different purpose — to
study the bluish arcs on
larger scales in the cluster,» said Chris O'Dea, professor in RIT's School of Physics and Astronomy and a co-author on the paper.